Results 51 to 60 of about 42,196 (291)

Attenuation of Candida albicans virulence with focus on disruption of its vacuole functions

Journal of Oral Microbiology, 2014
The objective of the present review is to discuss if the yeast vacuole can be used as a target for attenuation of Candida albicans virulence. Literature searches were made electronically using predetermined inclusion criteria. The main searches were made
Ingar Olsen
doaj   +1 more source

EUCAST breakpoints for antifungals.

, 2010
Item does not contain fulltextSusceptibility testing of fungi and development of interpretative breakpoints has become increasingly important due to the growing incidence of invasive fungal infections, the number and classes of antifungals, and the ...
Donnelly, J.P., Rodriguez-Tudela, J.L., Lass-Florl, C., Arendrup, M.C., Cuenca-Estrella, M., Lass-Flor, C.   +5 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Sclareolide as Antifungal Strategy Against Cryptococcus neoformans: Unveiling Its Mechanisms of Action

Microorganisms
Cryptococcal infection commonly begins as an opportunistic infection in humans, however, this can escalate to a systemic or life-threatening form in immunocompromised individuals. Here, we aim to identify novel antifungal molecules from plants resources.
Arumugam Ganeshkumar, Patricia Michelle Nagai de Lima, Jebiti Haribabu, Bruno Montanari Borges, Nycolas Willian Preite, Flavio Vieira Loures, Arunachalam Arulraj, Juliana Campos Junqueira   +7 more
doaj   +1 more source

Nanocarriers of Miconazole or Fluconazole: Effects on Three-Species Candida Biofilms and Cytotoxic Effects In Vitro

Journal of Fungi, 2021
The contribution of different Candida species in oral fungal infections has stimulated the search for more effective therapies. This study assessed the antibiofilm effects of nanocarriers of miconazole (MCZ) or fluconazole (FLZ) on Candida biofilms, and ...
Anne Caroline Morais Caldeirão, Heitor Ceolin Araujo, Laís Salomão Arias, Wilmer Ramírez Carmona, Gustavo Porangaba Miranda, Sandra Helena Penha Oliveira, Juliano Pelim Pessan, Douglas Roberto Monteiro   +7 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Antimicrobial Consumption among 66 Acute Care Hospitals in Catalonia: Impact of the COVID-19 Pandemic

Antibiotics, 2021
Background: Antimicrobials have been widely used during the COVID-19 pandemic. This study aimed to analyze the impact of the COVID-19 pandemic on the antimicrobial consumption of 66 hospitals in Catalonia.
Santiago Grau, Sergi Hernández, Daniel Echeverría-Esnal, Alexander Almendral, Ricard Ferrer, Enric Limón, Juan Pablo Horcajada, on behalf of the Catalan Infection Control Antimicrobial Stewardship Program (VINCat-PROA)   +7 more
doaj   +1 more source

Advancing SafeWax, A Bio‐Inspired Superhydrophobic Coating, Toward Sustainable and Climate‐Resilient Crop Protection

Advanced Functional Materials, EarlyView.
This study advances SafeWax, a bio‐inspired, fatty‐acids‐based superhydrophobic coating, by identifying an agriculturally compliant solvent and revealing how solvent‐controlled Fatty acid crystallization governs the coating's microscopic structure and performance.
Niv Ben‐Arie, Iryna Polishchuk, Franziska Tauber, Coralie Schneider, Elena Prudnikov, Alessia Calora, Silvia Milita, Simona Fermani, Mireia Alejandra Ibanez Revert, Ilaria Filippetti, Claudio Ratti, Matthias Kellermeier, Markus Rueckel, Boaz Pokroy   +13 more
wiley   +1 more source

Combined Toxicity of Microplastics and Antimicrobials on Animals: A Review

Antibiotics
Background/Objectives: Microplastics are ubiquitous pollutants that pose physical toxicity and serve as vectors for antimicrobial agents, altering their bioavailability and toxicity.
Kuok Ho Daniel Tang
doaj   +1 more source

Novel Cell Wall Antifungals Reveal a Special Synergistic Activity in pbr1 Mutants Resistant to the Glucan Synthesis Antifungals Papulacandins and Echinocandins

Frontiers in Microbiology, 2019
A series of 4-(arylmethylene)-3-isochromanones have been prepared with base-catalyzed Knoevenagel condensation starting from 3-isochromanone and aromatic aldehydes.
Rodrigo Berzaghi, Attila Agócs, María A. Curto, Gergely Gulyás-Fekete, Béla Kocsis, Juan C. Ribas, Tamás Lóránd   +6 more
doaj   +1 more source