Results 21 to 30 of about 2,264,666 (258)

Application of Cellular Technologies to the Experimental Treatment of Destructive Inflammatory Arthropathies

open access: yesCentral Asian Journal of Global Health, 2014
Introduction. The treatment of destructive inflammatory joint diseases (arthropathies) is one of the issues of current interest in modern medicine.
Marzhan Kaulambayeva   +2 more
doaj   +1 more source

Functional Characterization of a Dual Enhancer/Promoter Regulatory Element Leading Human CD69 Expression

open access: yesFrontiers in Genetics, 2020
The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells.
Jennifer Redondo-Antón   +6 more
doaj   +1 more source

Duality of β-glucan microparticles: antigen carrier and immunostimulants [PDF]

open access: yes, 2016
Designing efficient recombinant mucosal vaccines against enteric diseases is still a major challenge. Mucosal delivery of recombinant vaccines requires encapsulation in potent immunostimulatory particles to induce an efficient immune response. This paper
Baert, Kim   +4 more
core   +2 more sources

The cytolytic T lymphocyte response to the murine cytomegalovirus [PDF]

open access: yes, 1984
Limiting dilution (LD) analysis with two modifications, the expansion and the restimulation LD assay, led to the detection and quantification of two distinct in vivo maturation stages within the lineage of virus- specific self-restricted CTL after ...
Keil, Günther M.   +2 more
core   +4 more sources

Antigenic Variability [PDF]

open access: yesFrontiers in Immunology, 2020
Protective vaccines for hypervariable pathogens are urgently needed. It has been proposed that amputating highly variable epitopes from vaccine antigens would induce the production of broadly protective antibodies targeting conserved epitopes. However, so far, these approaches have failed, partially because conserved epitopes are occluded in vivo and ...
openaire   +3 more sources

Discriminating antigen and non-antigen using proteome dissimilarity: bacterial antigens [PDF]

open access: yesBioinformation, 2010
It has been postulated that immunogenicity results from the overall dissimilarity of pathogenic proteins versus the host proteome. We have sought to use this concept to discriminate between antigens and non-antigens of bacterial origin. Sets of 100 known antigenic and nonantigenic peptide sequences from bacteria were compared to human and mouse ...
Kamna Ramakrishnan, Darren R. Flower
openaire   +4 more sources

Screening of medicinal mushroom strains with antimicrobial activity and polysaccharides production

open access: yesTürk Biyokimya Dergisi, 2023
This study aimed to determine the antimicrobial activity of culture fluid and mycelial mass of selected Hericium strains from the IBK Mushroom Culture Collection (Kyiv, Ukraine) against bacteria and fungi, as well as to evaluate the potential of these ...
Narmuratova Zhanar   +10 more
doaj   +1 more source

Risk-associated factors associated with the bovine viral diarrhea virus in dromedary camels, sheep, and goats in abattoir surveillance and semi-closed herd system [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Bovine viral diarrhea virus (BVDV) is one of the most important viral pathogens causing high economic losses in cattle of all ages.
Abdullah I. A. Al-Mubarak   +6 more
doaj   +1 more source

Antigen Stability Controls Antigen Presentation [PDF]

open access: yesJournal of Biological Chemistry, 2004
We investigated whether protein stability controls antigen presentation using a four disulfide-containing snake toxin and three derivatives carrying one or two mutations (L1A, L1A/H4Y, and H4Y). These mutations were anticipated to increase (H4Y) or decrease (L1A) the antigen non-covalent stabilizing interactions, H4Y being naturally and frequently ...
Jean-Luc Tarride   +6 more
openaire   +3 more sources

SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies

open access: yesnpj Vaccines, 2023
This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh) and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-2-spike-ferritin-nanoparticle (SpFN) adjuvanted with either Army ...
Shikha Shrivastava   +27 more
doaj   +1 more source

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