Results 161 to 170 of about 3,953,720 (287)
Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis. [PDF]
Arthritis Res Ther, 2018 Di Ceglie I +13 more
europepmc +1 more source
JPGN Reports, EarlyView.Abstract Tezepelumab is a human monoclonal antibody that binds to human thymic stromal lymphopoietin (TSLP), an epithelial cytokine that plays a role in Type 2 signaling. We describe a 17‐year‐old with a history of eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis who demonstrated response to tezepelumab with both clinical and histologic ...
Destiny Newsome +3 more
wiley +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review
JEADV Clinical Practice, EarlyView.This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz +2 more
wiley +1 more source
TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu +8 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian +4 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT N6‐methyladenosine (m6A) plays a critical role in osteoarthritis (OA) pathogenesis. This study investigates the role of the m6A reader insulin‐like growth factor 2 mRNA‐binding protein 3 (IGF2BP3) in OA progression. OA models were established in vivo through destabilization of the medial meniscus (DMM) surgery in mice and in vitro by ...
Xing‐Shi Yuan +8 more
wiley +1 more source
Local but Not Systemic Administration of Uridine Prevents Development of Antigen-Induced Arthritis. [PDF]
PLoS One, 2015 Chenna Narendra S +3 more
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang +10 more
wiley +1 more source
IDO1 and TGF-β Mediate Protective Effects of IFN-α in Antigen-Induced Arthritis. [PDF]
J Immunol, 2016 Chalise JP +8 more
europepmc +1 more source