Results 211 to 220 of about 13,481 (242)

The Dynamics of a SEIR–SIRC Antigenic Drift Influenza Model

Bulletin of Mathematical Biology, 2017
We consider the dynamics of an influenza model with antigenic drift mechanism. Antigenic drift is an antigen mutation on the skin surface of the influenza virus that do not produce a new virus strain. The mutation produces the same virus but with slightly different antigens that cannot be recognized by the immune receptors formed by the previous ...
Fajar Adi-Kusumo
exaly   +4 more sources

Antigenic drift and variability of influenza viruses

Medical Microbiology and Immunology, 2002
Annual influenza epidemics are caused by rapid evolution of the viral genome. Continuous and extensive antigenic variation has been shown for hemagglutinin (HA), the principal immunizing antigen of the virus. Monitoring of the antigenicity of circulating influenza viruses is necessary for selection of the most suitable vaccine strains.
B, Schweiger, I, Zadow, R, Heckler
openaire   +2 more sources

Influenza Vaccine — Outmaneuvering Antigenic Shift and Drift

New England Journal of Medicine, 2004
The winter of 2003–2004 will be remembered as a year in which stories about influenza dominated the news and patients young and old clamored for influenza vaccination. This intense interest is the result of the confluence of multiple circumstances. The onset of the annual influenza epidemic came earlier than expected and was accompanied by reports of ...
openaire   +2 more sources

Antigenic drift, antigenic shift and interferon antagonists: how bunyaviruses counteract the immune system

Virus Research, 2002
Members of the Bunyaviridae family are amongst the most widespread viruses in the world. They can be found on every inhabited continent at virtually every latitude, and are able to infect a wide range of arthropods, plants and mammals including humans.
Weber, Friedemann, Elliott, Richard M.
openaire   +3 more sources

The Explanation of Antigenic Drift

1992
In the last chapter we saw that influenza is seasonal and that its seasonal epidemicity poses insoluble difficulties for the current concept that the virus survives solely by direct transmissions from the sick persons to cause influenza in their infected companions.
openaire   +1 more source

Antigenic Drift and Efficacy of Influenza Virus Vaccines, 1976-1977

Journal of Infectious Diseases, 1978
A unique opportunity occurred in February 1977 to assess the efficacy of an influenza virus vaccine given to military personnel in doses of 400 chick cell-agglutinating (CCA) units of A/Victoria/3/75, 400 CCA units of A/New Jersey/76, and 500 CCA units of B/Hong Kong/72 viruses.
G, Meiklejohn, T C, Eickhoff, P, Graves, J, I   +3 more
openaire   +2 more sources

Evolution of Antigen Drift/Switching: Continuously Evading Pathogens

Journal of Theoretical Biology, 1994
Following infection to a host, some pathogens repeatedly alter their antigen expression, and thereby escape the immune defense (antigen drift/switching). This paper examines the evolutionarily stable mutation rate of pathogens which maximizes the stationary pathogen density in a host.
openaire   +2 more sources

Antigenic shift and drift

Nature, 1980
openaire   +2 more sources

Cyclic Dynamics Caused by Antigenic Drift

2005
Traditionally, seasonal forcing has been considered to be the major cause of the influenza seasonality. However, Andreasen [2003] showed that repetitive introductions of new strains can lead to cyclic dynamics. The cyclic dynamic produced by his model is not seasonal, because the length of seasons cannot be defined in his model.
openaire   +1 more source

[Antigenic drift of type A and B influenza viruses].

Nihon rinsho. Japanese journal of clinical medicine, 1998
Epidemics of influenza of the past 10 years were reviewed by integrating records from Morbidity and Mortality Weekly Reports of the United States and Infectious Agents Surveillance Reports in Japan, as well as data of antigenic drift of epidemic strains. Nucleotide-sequencing analyses of field isolates have shown characteristic amino acid substitutions
openaire   +1 more source