PU-GRAIL: residue-level graph learning for identifying protective bacterial antigens under positive-unlabeled supervision. [PDF]
Jeon J, Jung S, Jung I, Kim K, Yeom J.
europepmc +1 more source
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Structural and functional dissection of neutralisation differences among SARS-CoV-2 variants using antigenicity prediction and CR3022 binding analysis. [PDF]
Sawant J, Patil A, Thakar M, Kurle S.
europepmc +1 more source
Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu +3 more
wiley +1 more source
Identification of Candidate epitopes from nation-enriched sequences in the African swine fever virus genomes. [PDF]
Kim S, Kim EB.
europepmc +1 more source
Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini +9 more
wiley +1 more source
Alignment-free prediction of cross-reactivity in influenza A (H3N2) anticipates antigenic drift. [PDF]
Forna A +9 more
europepmc +1 more source
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
wiley +1 more source
Molecular Characterization of DENV-1 Isolates From Pakistan Reveals Immunogenic Variability and Antiviral Potential of Phytochemicals Targeting the CprM Region. [PDF]
Shah SA, Shahid SA, Rahman S, Ali M.
europepmc +1 more source
Proteome-Based Antigen Screening and Multi-Epitope Design Against <i>Cutibacterium acnes</i>: An In Silico Study. [PDF]
Sripath K, E-Kobon T.
europepmc +1 more source

