Results 191 to 200 of about 50,210 (266)

Multi-epitope vaccine against nucleoprotein and envelopment polyprotein of Batai orthobunyavirus using molecular docking and molecular dynamics studies. [PDF]

Sci Rep
Naveed M, Asim M, Ali A, Amjad S, Majeed MN, Sandrine MNY, Al-Hoshani N, Mohamed RAEH, Alwethaynani MS, Almsaud MM.   +9 more
europepmc   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Immunoinformatic Design and Evaluation of a Multi-Epitope mRNA Vaccine RP14914P Targeting Latent Tuberculosis Infection. [PDF]

Pathogens
Tian Y, Zhang M, Ali SL, Abduldayeva A, Zhou S, An Y, Li Y, Ni R, Zhang L, Liu Y, Sun W, Gong W.   +11 more
europepmc   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

Editorial: Vaccines and molecular therapeutics for tuberculosis. [PDF]

Front Immunol
Sable SB, Velu V, Kupz A.
europepmc   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Pan-genome and reverse vaccinology for a multi-epitope vaccine against circulating post-2022 Monkeypox virus strains. [PDF]

PLoS One
Saber MA, Shovon MHJ, Imtiaz M, Tauhida SJ, Das S, Tareq MMI, Tripty MIA, Hossain MR, Siam LS, Zilani MNH, Saifullah, Rahman SMK, Khan U, Hasan MN.   +13 more
europepmc   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

A multi-stage in <i>silico</i> filtering approach for <i>Leishmania major</i> proteome for the identification of novel vaccine candidates.

Trop Parasitol
Abdulqader A, Arkah ZM, Ali F, Shamsir MS.   +3 more
europepmc   +1 more source

Integrative immunogenomic strategy for designing a multi-epitope vaccine against Zika and Dengue viruses. [PDF]

Sci Rep
Zubair A, Aldehri M, Shahani MY, Afghan N.   +3 more
europepmc   +1 more source