Results 41 to 50 of about 62,650 (255)

Evaluation of Antigenic Comparisons Among BVDV Isolates as it Relates to Humoral and Cell Mediated Responses

Frontiers in Veterinary Science, 2021
Antigenic differences between bovine viral diarrhea virus (BVDV) vaccine strains and field isolates can lead to reduced vaccine efficacy. Historically, antigenic differences among BVDV strains were evaluated using techniques based on polyclonal and ...
Shollie M. Falkenberg, Rohana P. Dassanayake, Brett Terhaar, Julia F. Ridpath, John D. Neill, James A. Roth   +5 more
doaj   +1 more source

Exploiting glycan topography for computational design of Env glycoprotein antigenicity [PDF]

, 2018
Mounting evidence suggests that glycans, rather than merely serving as a “shield”, contribute critically to antigenicity of the HIV envelope (Env) glycoprotein, representing critical antigenic determinants for many broadly neutralizing antibodies (bNAbs).
Todd J Suscovich, Bronwyn Gunn, Michael Seaman, Yu, Wen-Han, Suscovich, Todd J., Streeck, Hendrik, Christina B. Karsten (142441), Abraham L Brass, Peng Zhao, Lance Wells (95147), Michael Tiemeyer, Lauffenburger, Douglas A, Lance Wells, Lauffenburger, Douglas, Douglas A. Lauffenburger (115322), Peng Zhao (128233), Christina B Karsten, Wen-Han Yu (234340), Monia Draghi (5125829), Galit Alter (91383), Claudia Arevalo (3844972), Seaman, Michael, Hendrik Streeck, John R. Mascola (229761), Zhao, Peng, Lauffenburger, Douglas A., Monia Draghi, Todd J. Suscovich, Claudia Arevalo, Hendrik Streeck (91376), Galit Alter, Arevalo, Claudia, Abraham L. Brass, John R. Mascola, Douglas A. Lauffenburger, Todd J. Suscovich (562570), Tiemeyer, Michael, Alter, Galit, Douglas A Lauffenburger, Christina B. Karsten, Wen-Han Yu, Karsten, Christina, Karsten, Christina B., Wells, Lance, Gunn, Bronwyn, Mascola, John R., Bronwyn Gunn (5125835), Michael Tiemeyer (1348926), Brass, Abraham L., John R Mascola, Abraham L. Brass (199322), Michael Seaman (5125832), Draghi, Monia   +52 more
core   +1 more source

Physical properties of LBEs dominant epitopes and antigenicity.

, 2023
Physical properties of LBEs dominant epitopes and antigenicity.
Ce Niu (16814125), Yueyue He (10821234), Min Li (12799), Jianbing Ding (3449030), Zhengwei Yin (16814122), Mingkai Yu (11264445), Gulishati Haimiti (16814131), Juan Shi (122591), Xinru Xie (16814128), Wenhong Guo (16814134), Fengbo Zhang (220275)   +10 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

In-silico Antigenicity Determination and Clustering of Dengue Virus Serotypes [PDF]

, 2018
Emerging or re-emerging dengue virus (DENV) causes dengue fever epidemics globally. Current DENV serotypes are defined based on genetic clustering, while discrepancies are frequently observed between the genetic clustering and the antigenicity ...
Zhiliang Ji, Yuxuan Shang, Tianyi Qiu, Jingxuan Qiu   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Immunogenicity and Neutralization of Recombinant Vaccine Candidates Expressing F and G Glycoproteins against Nipah Virus

Vaccines
Nipah virus (NiV), of the Paramyxoviridae family, causes highly fatal infections in humans and is associated with severe neurological and respiratory diseases. Currently, no commercial vaccine is available for human use.
Seo Young Moon, Rochelle A. Flores, Min Su Yim, Heeji Lim, Seungyeon Kim, Seung Yun Lee, Yoo-kyoung Lee, Jae-Ouk Kim, Hyejin Park, Seong Eun Bae, In-Ohk Ouh, Woo H. Kim   +11 more
doaj   +1 more source

Physical properties of CTL dominant epitopes and antigenicity.

, 2023
Physical properties of CTL dominant epitopes and antigenicity.
Ce Niu (16814125), Yueyue He (10821234), Min Li (12799), Jianbing Ding (3449030), Zhengwei Yin (16814122), Mingkai Yu (11264445), Gulishati Haimiti (16814131), Juan Shi (122591), Xinru Xie (16814128), Wenhong Guo (16814134), Fengbo Zhang (220275)   +10 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Stability of vaccine strains of seasonal live attenuated influenza vaccines when adapted to MDCK cell culture

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Currently, the vast majority of influenza vaccines in the world are produced using developing chicken embryos as substrate, but there is an urgent necessity for transferring vaccine production to continuous cell lines, which would ensure ...
Victoria A. Matyushenko, Arina D. Kostromitina, Ekaterina A. Stepanova, Larisa G. Rudenko, Irina N. Isakova-Sivak   +4 more
doaj   +1 more source