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Bacterial antigens unleash tumor-targeting immunity

Cell Host & Microbe, 2023
The composition of the gut microbiome has been shown to influence disease outcome in patients with colorectal cancer (CRC). In a recent Nature Biotechnology article, Wang et al. demonstrate that killing CRC-associated bacteria with a liposomal antibiotic elicits CRC-targeting immune responses of therapeutic relevance as a consequence of epitope mimicry.
Nina, Boeck   +2 more
openaire   +2 more sources

Antigen Discovery in Bacterial Panproteomes

2020
There is still a lack of vaccines for many bacterial infections for which the best treatment option would be a prophylactic one. On the other hand, effectiveness has been questioned for some existing vaccines, prompting new developments. Therapeutic vaccines are also becoming a treatment option in specific cases where antibiotics tend to fail.
Daniel, Yero   +2 more
openaire   +2 more sources

Bacterial Antigen in the Kidney

New England Journal of Medicine, 1969
The role of bacterial infection in the pathogenesis of chronic pyelonephritis has been one of the fruitful areas of controversy in recent years.
openaire   +2 more sources

Immunology of bacterial polysaccharide antigens

Carbohydrate Research, 2003
Carbohydrates in the form of capsular polysaccharides and/or lipopolysaccharides are the major components on the surface of bacteria. These molecules are important virulence factors in many bacteria isolated from infected persons. Immunity against these components confers protection against the disease.
openaire   +2 more sources

Bacterial antigen detection test in meningitis

The Indian Journal of Pediatrics, 2003
To evaluate the role of bacterial antigen detection test in cerebrospinal fluid (CSF) for a rapid etiological diagnosis of bacterial meningitis.The study included 36 cases of bacterial meningitis and 14 controls. Latex particle agglutination test (LPA test) for detection of bacterial antigen was done in the CSF using slidex meningitis kit (Biomeriux ...
B K, Das   +3 more
openaire   +2 more sources

Antigenicity of a Bacterial Deoxyribonucleic Acid

Nature, 1958
SINCE earlier evidence (refs. 1–3 and Medawar, P. B., personal communication) suggesting a serological reactivity for deoxyribonucleic acid (or the deoxyribonueleic acid moiety of a nucleoprotein) has been indirect or controversial, the problem has been re-investigated with the aid of a preparation rich in deoxyribonucleic acid with transforming ...
J H, PHILLIPS, W, BRAUN, O J, PLESCIA
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Bacterial ghosts as antigen delivery vehicles

Advanced Drug Delivery Reviews, 2005
The bacterial ghost system is a novel vaccine delivery system unusual in that it combines excellent natural intrinsic adjuvant properties with versatile carrier functions for foreign antigens. The efficient tropism of bacterial ghosts (BG) for antigen presenting cells promotes the generation of both cellular and humoral responses to heterologous ...
Ulrike Beate, Mayr   +5 more
openaire   +3 more sources

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