Antibody-Antibiotic Conjugates: Mechanisms, Clinical Progress, and Next-Generation Strategies Against Multidrug-Resistant Bacterial Infections. [PDF]
Askari P +3 more
europepmc +1 more source
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang +3 more
wiley +1 more source
Frontiers in bacterial outer membrane vesicles: From basic characteristics to cancer therapy. [PDF]
Ma S +6 more
europepmc +1 more source
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs +4 more
wiley +1 more source
No more than three PlpE non-overlapping epitopes trigger significant antibody production in individuals vaccinated with the <i>Pasteurella multocida</i> epitope-chimeric proteins. [PDF]
Geng B, Zhou B, Zhang Z, Jiang G, Zhu W.
europepmc +1 more source
A protocol of fs‐laser‐induced periodic phase‐transition of 2D‐MoTe2 template, inducing AuNPs@1T’‐MoTe2 nanograting, is developed. The labeled AuNPs@1T’‐MoTe2 substrate conjugated with specialized immunoglobulin G demonstrates an unexpectedly high discrimination accuracy close to unity for serological diagnosis of rheumatoid arthritis by frequency ...
Yao Yao +9 more
wiley +1 more source
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Delayed-Type Hypersensitivity to <i>Mycobacterium tuberculosis</i> Antigens: The Immunological Mechanism and Potential Therapeutic Strategies-A Systematic Review. [PDF]
Andryszkiewicz W +5 more
europepmc +1 more source
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju +5 more
wiley +1 more source
<i>Lactococcus lactis</i> as a New Strategy for Oral Vaccination: Current Insights and Future Perspectives. [PDF]
Grossolli-Galvez J +3 more
europepmc +1 more source

