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A Comprehensive Review on Bacterial Vaccines Combating Antimicrobial Resistance in Poultry [PDF]

open access: yesVaccines, 2023
Bacterial vaccines have become a crucial tool in combating antimicrobial resistance (AMR) in poultry. The overuse and misuse of antibiotics in poultry farming have led to the development of AMR, which is a growing public health concern.
Md. Saiful Islam, Md. Tanvir Rahman
doaj   +2 more sources

Challenges and Opportunities of Bacterial Vaccines as Alternatives to Antimicrobials in Swine Health Management: Insights from U.S. Veterinarians [PDF]

open access: yesPathogens
Antimicrobial resistance (AMR) is a significant global health concern, and the use of antibiotics in livestock, including swine production, is a major contributor.
Xirui Zhang   +16 more
doaj   +2 more sources

From Antibiotic Resistance to Bacterial Vaccines: A New Approach to Controlling Resistant Bacterial Infections [PDF]

open access: yesInfection and Drug Resistance
Feiyang Xiong,1,2,* Xiayi Fang,1,* Yanping Lu,3 Wenliang Lv2 1Hunan University of Chinese Medicine, Changsha, Hunan, People’s Republic of China; 2Department of Infection, Guang’anmen Hospital, China Academy of Chinese Medical Sciences ...
Xiong F, Fang X, Lu Y, Lv W
doaj   +2 more sources

Combined effects of glycan chain length and linkage type on the immunogenicity of glycoconjugate vaccines

open access: yesnpj Vaccines, 2021
The development and use of antibacterial glycoconjugate vaccines have significantly reduced the occurrence of potentially fatal childhood and adult diseases such as bacteremia, bacterial meningitis, and pneumonia.
Chakkumkal Anish   +2 more
doaj   +1 more source

Clinical trial of tolerability, safety, and immunogenicity of the Russian influenza inactivated split vaccine Flu-m in children from 6 months to 9 years of age

open access: yesЖурнал инфектологии, 2023
Purpose: To study the reactogenicity, safety and immunogenicity of the Russian vaccine Flu-M in comparison with Vaxigrip vaccine for influenza prevention in children aged from 6 months to 9 years (phase III).Materials and Methods.
A. M. Korolyuk   +8 more
doaj   +1 more source

IMMUNOGENICITY OUTCOMES OF A RANDOMIZED, MULTICENTER, INTERVENTIONAL, FIRST-IN-HUMAN, PHASE 1/2A STUDY OF VAC52416 (EXPEC10V), A VACCINE CANDIDATE FOR THE PREVENTION OF INVASIVE ESCHERICHIA COLI DISEASE

open access: yesInternational Journal of Infectious Diseases, 2023
Intro: The safety, reactogenicity, and immunogenicity of VAC52416 (ExPEC10V), a vaccine candidate to prevent invasive Escherichia coli disease, was assessed in a phase 1/2a study (NCT03819049). Results from Cohort 1 have been presented. Here, we describe
C. Fierro   +9 more
doaj   +1 more source

Chikungunya vaccines: advances in the development and prospects for marketing approval

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Chikungunya fever is an acute infectious disease caused by the mosquito-borne Chikungunya virus (CHIKV). In the last decades, cases of the disease have been reported in more than 100 countries; therefore, CHIKV presents a global public health problem ...
E. V. Otrasheuskaja   +3 more
doaj   +1 more source

Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance [PDF]

open access: yes, 2008
Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases. Ideally, room temperature stable dry formulations of live bacterial vaccines will allow oral vaccination ...
Edwards, Alexander D.   +1 more
core   +1 more source

Protein Antigens Increase the Protective Efficacy of a Capsule-Based Vaccine against Staphylococcus aureus in a Rat Model of Osteomyelitis [PDF]

open access: yes, 2014
Staphylococcus aureus is an invasive bacterial pathogen, and antibiotic resistance has impeded adequate control of infections caused by this microbe. Moreover, efforts to prevent human infections with single-component S. aureus vaccines have failed.
Buzzola, Fernanda Roxana   +6 more
core   +2 more sources

High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis

open access: yesMicrobial Cell Factories, 2018
Background Outer membrane vesicles (OMVs) are nanoparticles released by Gram-negative bacteria and can be used as vaccines. Often, detergents are used to promote release of OMVs and to remove the toxic lipopolysaccharides.
Matthias J. H. Gerritzen   +6 more
doaj   +1 more source

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