Results 1 to 10 of about 1,232,742 (295)

Bacterial vaccines in poultry [PDF]

Bulletin of the National Research Centre, 2020
AbstractBackgroundPoultry bacterial pathogens are mainly controlled by using high-cost sanitary measures and medical treatment. However, the drug-resistant strains of pathogens continuously emerge, and medical treatments are often ineffective. Moreover, there is increasing public objections to drug residues in poultry products. The other important type
Nagwa S. Rabie, Zeinab M. S. Amin Girh
openaire   +4 more sources

Combined effects of glycan chain length and linkage type on the immunogenicity of glycoconjugate vaccines

npj Vaccines, 2021
The development and use of antibacterial glycoconjugate vaccines have significantly reduced the occurrence of potentially fatal childhood and adult diseases such as bacteremia, bacterial meningitis, and pneumonia.
Chakkumkal Anish, Michel Beurret, Jan Poolman   +2 more
doaj   +1 more source

Clinical trial of tolerability, safety, and immunogenicity of the Russian influenza inactivated split vaccine Flu-m in children from 6 months to 9 years of age

Журнал инфектологии, 2023
Purpose: To study the reactogenicity, safety and immunogenicity of the Russian vaccine Flu-M in comparison with Vaxigrip vaccine for influenza prevention in children aged from 6 months to 9 years (phase III).Materials and Methods.
A. M. Korolyuk, L. A. Zazimko, V. N. Kraeva, Yu. A. Koromzin, E. A. Ruzanova, A. A. Ekimov, N. N. Savina, E. V. Ryskova, V. P. Trukhin   +8 more
doaj   +1 more source

IMMUNOGENICITY OUTCOMES OF A RANDOMIZED, MULTICENTER, INTERVENTIONAL, FIRST-IN-HUMAN, PHASE 1/2A STUDY OF VAC52416 (EXPEC10V), A VACCINE CANDIDATE FOR THE PREVENTION OF INVASIVE ESCHERICHIA COLI DISEASE

International Journal of Infectious Diseases, 2023
Intro: The safety, reactogenicity, and immunogenicity of VAC52416 (ExPEC10V), a vaccine candidate to prevent invasive Escherichia coli disease, was assessed in a phase 1/2a study (NCT03819049). Results from Cohort 1 have been presented. Here, we describe
C. Fierro, M. Sarnecki, J. Doua, B. Spiessens, O. Go, T. Davies, G. van den Dobbelsteen, J. Poolman, D. Abbanat, W. Haazen   +9 more
doaj   +1 more source

Chikungunya vaccines: advances in the development and prospects for marketing approval

Биопрепараты: Профилактика, диагностика, лечение, 2023
Chikungunya fever is an acute infectious disease caused by the mosquito-borne Chikungunya virus (CHIKV). In the last decades, cases of the disease have been reported in more than 100 countries; therefore, CHIKV presents a global public health problem ...
E. V. Otrasheuskaja, V. P. Trukhin, V. A. Merkulov, G. M. Ignatyev   +3 more
doaj   +1 more source

Composing of an oil adjuvant containing BCG as an immunomodulating for rabbit clostridial enterotoxaemia and bloat vaccine [PDF]

Veterinary Medical Journal - Giza, 2022
Clostridium perfringens (C. perfringens) is one of the most important pathogen that is widely distributed in all over the world and responsible for many diseases among life stock.
Hamed ElHelw, Shereen Fouad, Marwah Mohamed, Gina Mohammed, Alaa ElKholy   +4 more
doaj   +1 more source

High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis

Microbial Cell Factories, 2018
Background Outer membrane vesicles (OMVs) are nanoparticles released by Gram-negative bacteria and can be used as vaccines. Often, detergents are used to promote release of OMVs and to remove the toxic lipopolysaccharides.
Matthias J. H. Gerritzen, Ronald H. W. Maas, Jan van den Ijssel, Lonneke van Keulen, Dirk E. Martens, René H. Wijffels, Michiel Stork   +6 more
doaj   +1 more source

Characterization of Lactobacilli Phage Endolysins and Their Functional Domains–Potential Live Biotherapeutic Testing Reagents

Viruses, 2023
Phage endolysin-specific binding characteristics and killing activity support their potential use in biotechnological applications, including potency and purity testing of live biotherapeutic products (LBPs).
Robert J. Dorosky, Stephanie L. Lola, Haleigh A. Brown, Jeremy E. Schreier, Sheila M. Dreher-Lesnick, Scott Stibitz   +5 more
doaj   +1 more source

Analysis of pneumococcal serotypes distribution to determine a model composition for a Russian pneumococcal conjugate vaccine

Биопрепараты: Профилактика, диагностика, лечение, 2022
Diseases caused by Streptococcus pneumoniae, as well as antibiotic resistance of its serotypes, are the leading cause of death amongst children worldwide.
V. P. Trukhin, A. E. Evtushenko, E. L. Salimova, A. D. Konon, M. R. Khaitov, V. A. Merkulov   +5 more
doaj   +1 more source

REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF DOMESTIC FLU-M INACTIVATED SPLIT INFLUENZA VACCINE FOR THE IMMUNIZATION OF ADULTS AGED BETWEEN 18 AND 60

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. The research was aimed at evaluating the reactogenicity, safety and immunogenicity of Flu-M inactivated split influenza vaccine. Materials and methods.
I. V. Feldblyum, K. A. Subbotina, S. D. Novgorodova, G. M. Ignatev, M. Kh. Alyeva, M. K. Erofeeva, V. G. Orlovsky, I. A. Leneva, S. Ya. Melnikov, E. V. Kazakova, E. P. Nacharova, V. P. Trukhin   +11 more
doaj   +1 more source