Results 31 to 40 of about 212,352 (206)

National Institute of Allergy and Infectious Diseases workshop report: "Chlamydia vaccines: The way forward". [PDF]

, 2019
Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic ...
Brunham, Robert C, Darville, Toni, de la Maza, Luis M, Deal, Carolyn, Zhong, Guangming   +4 more
core   +1 more source

A human Lyme disease vaccine: two steps forward on the path to prevention

Expert Review of Vaccines
Introduction Lyme disease is caused by the tick-borne spirochete pathogen Borrelia burgdorferi sensu lato (s.l.). Outer surface protein A (OspA) is expressed by B. burgdorferi s.l.
Raphael Simon, Erik Lamberth, James H. Stark, Julie M. Skinner   +3 more
doaj   +1 more source

Toward an Improved Meningococcal Serogroup B Assay

mBio, 2018
Because of diverse sequences and differential expression of surface structures on individual invasive Neisseria meningitidis serogroup B (MenB) strains, predicting the efficacy of MenB vaccines using traditional human serum bactericidal assays (hSBA) is ...
Jan Poolman
doaj   +1 more source

TECHNOLOGY OF OBTAINING POLYRIBOSYLRIBITOL PHOSPHATE AS AN ACTIVE PHARMACEUTICAL INGREDIENT FOR THE PRODUCTION OF POLYSACCHARIDE VACCINES

Фармация и фармакология (Пятигорск), 2018
Despite the world practice, in the Russian Federation immunization against hemophilic infection is carried out only for the children from risk groups, which may be due to the lack of production of this vaccine in the Russian Federation.
E. L. Salimova, A. D. Konon, V. P. Truhin, I. V. Krasilnikov   +3 more
doaj   +1 more source

Clinical burden of invasive Escherichia coli disease among older adult patients treated in hospitals in the United States

BMC Infectious Diseases, 2023
Background Invasive extraintestinal pathogenic Escherichia coli disease (IED) can lead to severe outcomes, particularly among older adults. However, the clinical burden of IED in the U.S. has not been well characterized.
Luis Hernandez-Pastor, Jeroen Geurtsen, Bryan Baugh, Antoine C. El Khoury, Nnanya Kalu, Marjolaine Gauthier-Loiselle, Rebecca Bungay, Martin Cloutier, Michal Sarnecki, Elie Saade   +9 more
doaj   +1 more source

Population, sexual and reproductive health, rights and sustainable development: forging a common agenda. [PDF]

, 2010
This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate ...
Campbell, D. M., Carter, P. E., Collins-Emerson, J. M., French, N. P., Hathaway, S., Marshall, J., Midwinter, A. C., Mullner, P., Pirie, R., Shadbolt, T., Spencer, Simon E. F., Wilson, D. J.   +11 more
core   +1 more source

A SpA+LukAB vaccine targeting Staphylococcus aureus evasion factors restricts infection in two minipig infection models

npj Vaccines
Staphylococcus aureus is a major cause of bacterial infection-related deaths. Increasing antimicrobial resistance highlights the urgent need for effective preventative strategies.
Jan T. Poolman, Victor J. Torres, Dominique Missiakas, Suzanne P. M. Welten, Jeffrey Fernandez, Ashley L. DuMont, Anna O’Keeffe, Sergey R. Konstantinov, Brian Morrow, Peter Burghout, Jan Grijpstra, Miranda M. C. van Beers, Chakkumkal Anish, Michel Beurret, Jeroen Geurtsen, Pauline M. L. Rood, Oliver Koeberling, Miaomiao Shi, Germie P. J. M. van den Dobbelsteen   +18 more
doaj   +1 more source

PECULIARITIES OF CULTIVATION OF HAEMOPHILUS INFLUENZAE TYPE B STRAINS - PRODUCERS OF POLYRIBOSYLRIBITOL PHOSPHATE - THE MAIN COMPONENT OF POLYSACCHARIDE VACCINES

Фармация и фармакология (Пятигорск), 2017
One of the up-to-date challenges of modern immunobiotechnology is the development and introduction of an effective vaccine against the infection caused by the bacterium Haemophilus influenza, type b (Hib). The main active substance of the vaccine against
E. L. Salimova, A. D. Konon, S. V. Petrovskii, V. P. Truhin, I. V. Krasilnikov   +4 more
doaj   +1 more source

Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza [PDF]

, 2012
WAcute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008, and the main pathogens ...
Black, Catto, Choudhuri, George, Graham, Higginson, Horwood, Huda, Lawn, Nair, Nair, Nair, O'Brien, Osterholt, Rudan, Rudan, Rudan, Rudan, Rudan, Tomlinson, Watt, Webster   +21 more
core   +3 more sources

Clinical trial of tolerability, safety and immunogenicity of influenza inactivated split-vaccine Flu-M in children aged 6 to 17 years

Журнал инфектологии
Purpose. To evaluate the tolerability, safety and immunogenicity of influenza inactivated split flu vaccine Flu-M during single immunization of children aged 6 to 17 years.Materials and methods.
A. M. Korolyuk, V. N. Kraeva, L. A. Zazimko, Yu. A. Koromzin, E. A. Ruzanova, N. N. Savina, E. V. Ryskova   +6 more
doaj   +1 more source