Results 31 to 40 of about 129,578 (294)

Recent Progress in Shigella and Burkholderia pseudomallei Vaccines

open access: yes, 2021
Significant advancement has been made in the development of vaccines against bacterial pathogens. However, several roadblocks have been found during the evaluation of vaccines against intracellular bacterial pathogens.
Nittaya Khakhum   +3 more
core   +1 more source

Characterization of Lactobacilli Phage Endolysins and Their Functional Domains–Potential Live Biotherapeutic Testing Reagents

open access: yesViruses, 2023
Phage endolysin-specific binding characteristics and killing activity support their potential use in biotechnological applications, including potency and purity testing of live biotherapeutic products (LBPs).
Robert J. Dorosky   +5 more
doaj   +1 more source

Dose-specific efficacy of Haemophilus influenzae type b conjugate vaccines: a systematic review and meta-analysis of controlled clinical trials. [PDF]

open access: yes, 2012
Global coverage of infant Haemophilus influenzae type b (Hib) vaccination has increased considerably during the past decade, partly due to GAVI Alliance donations of the vaccine to low-income countries. In settings where large numbers of children receive
Clark, A   +6 more
core   +1 more source

Vaccines against bacterial meningitis [PDF]

open access: yesBritish Medical Bulletin, 2004
Meningitis remains an important cause of morbidity and mortality among children >5 years of age and is especially prevalent in developing countries. Effective routine immunization against Hib, pneumococcus and serogroupC meningococcus has had a significant impact on both invasive disease and carriage caused by these encapsulated bacteria.
Segal, S, Pollard, A
openaire   +3 more sources

Analysis of pneumococcal serotypes distribution to determine a model composition for a Russian pneumococcal conjugate vaccine

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2022
Diseases caused by Streptococcus pneumoniae, as well as antibiotic resistance of its serotypes, are the leading cause of death amongst children worldwide.
V. P. Trukhin   +5 more
doaj   +1 more source

REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF DOMESTIC FLU-M INACTIVATED SPLIT INFLUENZA VACCINE FOR THE IMMUNIZATION OF ADULTS AGED BETWEEN 18 AND 60

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. The research was aimed at evaluating the reactogenicity, safety and immunogenicity of Flu-M inactivated split influenza vaccine. Materials and methods.
I. V. Feldblyum   +11 more
doaj   +1 more source

Efficacy, safety, and immunogenicity of the Shigella sonnei 1790GAHB GMMA candidate vaccine: Results from a phase 2b randomized, placebo-controlled challenge study in adults

open access: yesEClinicalMedicine, 2021
Background: Shigellosis accounts for substantial morbidity and mortality worldwide and is the second most common cause of moderate and severe diarrhoea in children.
Robert W. Frenck, Jr   +23 more
doaj   +1 more source

Target identification for prevention and therapy of "Salmonella" infections [PDF]

open access: yes, 2014
In this thesis we investigated maintenance requirements of Salmonella during chronic infections, and determined the relevant antigen properties that might facilitate the development of Salmonella vaccines. Overall, we wanted to achieve two goals: a)To
Barat, Somedutta
core   +1 more source

BACTERIAL VACCINE THERAPY [PDF]

open access: yesJournal of the American Medical Association, 1917
"If at the present time ten years of public notoriety have passed over any doctrine professing to be of importance in medical science, and if it has not succeeded in raising up a powerful body of able, learned, and ingenious advocates for its claims, the fault must be in the doctrine and not in the medical profession." This old criterion of Holmes is ...
openaire   +2 more sources

Assembly, Biochemical Characterization, Immunogenicity, Adjuvanticity, and Efficacy of Shigella Artificial Invaplex

open access: yesmSphere, 2018
The native Invaplex (InvaplexNAT) vaccine and adjuvant is an ion exchange-purified product derived from the water extract of virulent Shigella species.
K. Ross Turbyfill   +4 more
doaj   +1 more source

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