Results 51 to 60 of about 1,154,986 (294)

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Clinical trial of tolerability, safety and immunogenicity of influenza inactivated split-vaccine Flu-M in children aged 6 to 17 years

Журнал инфектологии
Purpose. To evaluate the tolerability, safety and immunogenicity of influenza inactivated split flu vaccine Flu-M during single immunization of children aged 6 to 17 years.Materials and methods.
A. M. Korolyuk, V. N. Kraeva, L. A. Zazimko, Yu. A. Koromzin, E. A. Ruzanova, N. N. Savina, E. V. Ryskova   +6 more
doaj   +1 more source

TECHNOLOGY OF OBTAINING POLYRIBOSYLRIBITOL PHOSPHATE AS AN ACTIVE PHARMACEUTICAL INGREDIENT FOR THE PRODUCTION OF POLYSACCHARIDE VACCINES

Фармация и фармакология (Пятигорск), 2018
Despite the world practice, in the Russian Federation immunization against hemophilic infection is carried out only for the children from risk groups, which may be due to the lack of production of this vaccine in the Russian Federation.
E. L. Salimova, A. D. Konon, V. P. Truhin, I. V. Krasilnikov   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Comparison of the number of Lyme neuroborreliosis cases in European Centre for Disease Prevention and Control (ECDC) data and national public surveillance reports, 2018–2023

Ticks and Tick-Borne Diseases
Lyme borreliosis (LB) is the most common vector-borne disease in Europe. At least 29 European Economic Area (EEA) countries publish online LB surveillance reports.
Alexander Davidson, Frederick J. Angulo, Julie Davis, Kate Halsby, Gordon Brestrich, Jennifer C. Moïsi, James H. Stark   +6 more
doaj   +1 more source

PECULIARITIES OF CULTIVATION OF HAEMOPHILUS INFLUENZAE TYPE B STRAINS - PRODUCERS OF POLYRIBOSYLRIBITOL PHOSPHATE - THE MAIN COMPONENT OF POLYSACCHARIDE VACCINES

Фармация и фармакология (Пятигорск), 2017
One of the up-to-date challenges of modern immunobiotechnology is the development and introduction of an effective vaccine against the infection caused by the bacterium Haemophilus influenza, type b (Hib). The main active substance of the vaccine against
E. L. Salimova, A. D. Konon, S. V. Petrovskii, V. P. Truhin, I. V. Krasilnikov   +4 more
doaj   +1 more source

Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines. [PDF]

, 2014
Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a large scale and free of contaminating bacterial toxins and antigens.
G. C. Whitelam (7665758), Marie Goldrick (324989), Roberts Ian S., Garry C. Whitelam (519301), Andrew, PW, Patel, Alexandra J.F., Whitelam, Garry C, Claire M. Smith (7665743), Peter W. Andrew (153608), Roberts, Ian S, Whitelam, Garry C., Patel Alexandra J. F., Roberts, IS, K. C. Gough (7665749), Glenn, S, Gough Kevin C., Andrew, Peter W, S. C. Fry (7665746), Alexandra J F Patel, Stephen C Fry, Garry C Whitelam, Kevin C Gough, Gough, KC, Sarah Glenn (519300), Fry Stephen C., Andrew Peter W., Gough, Kevin C, Whitelam, GC, Sarah Glenn, Fry, Stephen C., Claire M. Smith (519296), Roberts, Ian S., Ian S. Roberts (159693), Whitelam Garry C., Peter W Andrew, Smith, Claire M, Patel, Alexandra J F, Patel, AJ, Fry, Stephen C, Stephen C. Fry (519297), Andrew, Peter W., Kevin C. Gough (519298), Ian S Roberts, Fry, SC, Goldrick, M, Smith Claire M., Alexandra J. F. Patel (519299), Goldrick Marie, Marie Goldrick, M. Goldrick (7665755), Goldrick, Marie, Alexandra J. F. Patel (7665752), Gough, Kevin C., Glenn, Sarah, Glenn Sarah, Smith, Claire M., Claire M Smith, Smith, CM, I. S. Roberts (6341096)   +58 more
core   +1 more source

A randomized phase 1/2a trial of ExPEC10V vaccine in adults with a history of UTI

npj Vaccines
The safety, reactogenicity, and immunogenicity of 3 doses of ExPEC10V (VAC52416), a vaccine candidate to prevent invasive Escherichia coli disease, were assessed in a phase 1/2a study (NCT03819049). In Cohort 1, ExPEC10V was well tolerated; the high dose
Carlos A. Fierro, Michal Sarnecki, Bart Spiessens, Oscar Go, Tracey A. Day, Todd A. Davies, Germie van den Dobbelsteen, Jan Poolman, Darren Abbanat, Wouter Haazen   +9 more
doaj   +1 more source

Tick-Borne Encephalitis Vaccine Effectiveness and Impact in Slovenia, 2019–2024

Pathogens
Slovenia has a high tick-borne encephalitis (TBE) incidence and TBE vaccination is recommended for all residents ≥1 year-of-age. Despite widespread TBE vaccine use in Slovenia, TBE vaccine effectiveness (VE) has not been reported for Slovenia. We defined
Jan Kordež, Frederick J. Angulo, Pingping Zhang, Alexander Davidson, Juanita Edwards, Lisa R. Harper, Andreas Pilz, Hannah Gould   +7 more
doaj   +1 more source

Use of Carbopol as an adjuvant in preparation of inactivated rabbit pasteurellosis vaccine [PDF]

Benha Veterinary Medical Journal
The current study was designed to investigate the immunological response of rabbits vaccinated with the rabbit pasteurellosis vaccine adjuvanted with Carbopol®. One hundred and twenty, 2 weeks old rabbits were divided into four groups, 30 for each.
Naglaa Ali, Fatma Ibrahim, Manal Mohamed, Wafaa Abd El-Moneim   +3 more
doaj   +1 more source