Results 61 to 70 of about 129,578 (294)

Comparison of the number of Lyme neuroborreliosis cases in European Centre for Disease Prevention and Control (ECDC) data and national public surveillance reports, 2018–2023

open access: yesTicks and Tick-Borne Diseases
Lyme borreliosis (LB) is the most common vector-borne disease in Europe. At least 29 European Economic Area (EEA) countries publish online LB surveillance reports.
Alexander Davidson   +6 more
doaj   +1 more source

TECHNOLOGY OF OBTAINING POLYRIBOSYLRIBITOL PHOSPHATE AS AN ACTIVE PHARMACEUTICAL INGREDIENT FOR THE PRODUCTION OF POLYSACCHARIDE VACCINES

open access: yesФармация и фармакология (Пятигорск), 2018
Despite the world practice, in the Russian Federation immunization against hemophilic infection is carried out only for the children from risk groups, which may be due to the lack of production of this vaccine in the Russian Federation.
E. L. Salimova   +3 more
doaj   +1 more source

Biological safety concepts of genetically modified live bacterial vaccines

open access: yes, 2007
Live vaccines possess the advantage of having access to induce cell-mediated and antibody-mediated immunity; thus in certain cases they are able to prevent infection, and not only disease. Furthermore, live vaccines, particularly bacterial live vaccines,
Frey, Joachim
core   +1 more source

Monitoring the introduction of pneumococcal conjugate vaccines into West Africa: design and implementation of a population-based surveillance system. [PDF]

open access: yes, 2012
Routine use of pneumococcal conjugate vaccines (PCVs) in developing countries is expected to lead to a significant reduction in childhood deaths. However, PCVs have been associated with replacement disease with non-vaccine serotypes.
Greenwood, Brian M   +55 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

Use of Carbopol as an adjuvant in preparation of inactivated rabbit pasteurellosis vaccine [PDF]

open access: yesBenha Veterinary Medical Journal
The current study was designed to investigate the immunological response of rabbits vaccinated with the rabbit pasteurellosis vaccine adjuvanted with Carbopol®. One hundred and twenty, 2 weeks old rabbits were divided into four groups, 30 for each.
Naglaa Ali   +3 more
doaj   +1 more source

Clinical burden of invasive Escherichia coli disease among older adult patients treated in hospitals in the United States

open access: yesBMC Infectious Diseases, 2023
Background Invasive extraintestinal pathogenic Escherichia coli disease (IED) can lead to severe outcomes, particularly among older adults. However, the clinical burden of IED in the U.S. has not been well characterized.
Luis Hernandez-Pastor   +9 more
doaj   +1 more source

An investigation of novel DNA based vaccines for protection against Brucellosis [PDF]

open access: yes
This thesis describes design, construction and evaluation in a BALB/c mouse model, for five novel Brucella specific DNA vaccines. Brucellosis is worldwide zoonosis of economic significance that poses a significant threat to both animal and human health ...
Commander, Nicola Jane
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

A randomized phase 1/2a trial of ExPEC10V vaccine in adults with a history of UTI

open access: yesnpj Vaccines
The safety, reactogenicity, and immunogenicity of 3 doses of ExPEC10V (VAC52416), a vaccine candidate to prevent invasive Escherichia coli disease, were assessed in a phase 1/2a study (NCT03819049). In Cohort 1, ExPEC10V was well tolerated; the high dose
Carlos A. Fierro   +9 more
doaj   +1 more source

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