Results 71 to 80 of about 129,578 (294)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Development of Phage Lysin LysA2 for Use in Improved Purity Assays for Live Biotherapeutic Products

open access: yesViruses, 2015
Live biotherapeutic products (LBPs), commonly referred to as probiotics, are typically preparations of live bacteria, such as Lactobacillus and Bifidobacterium species that are considered normal human commensals.
Sheila M. Dreher-Lesnick   +2 more
doaj   +1 more source

The History, Present and Future of Allergen Standardization in the United States and Europe

open access: yesFrontiers in Immunology, 2021
The topic of standardization in relation to allergen products has been discussed by allergists, regulators, and manufacturers for a long time. In contrast to synthetic medicinal products, the natural origin of allergen products makes the necessary ...
Julia Zimmer   +5 more
doaj   +1 more source

A lucky career in bacterial vaccines [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2012
(2012). A lucky career in bacterial vaccines. Human Vaccines & Immunotherapeutics: Vol. 8, No. 4, pp. 420-422.
openaire   +2 more sources

Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings

open access: yesAdvanced Materials, EarlyView.
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed   +9 more
wiley   +1 more source

Immunity to Intracellular Salmonella Depends on Surface-associated Antigens [PDF]

open access: yes, 2012
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum.
Rizos Konstantin   +50 more
core   +1 more source

Determination of Endotoxicity in Bacterial Vaccines [PDF]

open access: yesApplied Microbiology, 1973
Endotoxicity of bacterial vaccines was quantitated in mice by using actinomycin D as potentiating agent. The results were compared with those obtained by the mouse weight gain test. The lethality of Escherichia coli lipopolysaccharide was increased 2,140 times when 12.5 μg of actinomycin D ...
K H, Wong   +3 more
openaire   +2 more sources

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

open access: yesAdvanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang   +9 more
wiley   +1 more source

Serotyping and Cross-Reactivity’s Between Different Pseudomonas aeruginosa Isolates Prevalent in Iran

open access: yesIranian Journal of Microbiology, 2010
Background and Objectives: 300 Pseudomonas aeruginosa strains were isolated from hospitalized patients in Iran. Using international antigenic typing system (IATS) antibodies, all strains were classified into 16 serotypes while serotype 14 was not ...
H Ahmadi   +9 more
doaj  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

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