Results 91 to 100 of about 129,985 (296)

A qualitative burden of disease study in patients with invasive Escherichia coli disease aged ≥ 60 years in the United States

BMC Infectious Diseases
Background Invasive Escherichia coli disease (IED) comprises a diverse range of severe infections caused by E. coli, mainly affecting neonates and older adults, and is associated with severe and sometimes fatal outcomes.
Mark A. Schmidt, Inga Gruß, James V. Davis, Judy Donald, Kelly McQuarrie, Michal Sarnecki, Joachim Doua, Luis Hernandez Pastor, Jeroen Geurtsen, Cristina Valencia, Elvira Carrió, Thomas Verstraeten, Antoine C. El Khoury   +12 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Stability Study of Iriba Brucellosis Full-dose and Reduced-dose Vaccine Produced by Razi Institute in Iran

Archives of Razi Institute, 2015
Stability study of biological products plays an important role for determination of product changes in maintenance period and ensuring of safety and efficacy of vaccines.
Hasannia, E., Soleimani, S., Alamian, S., Behrozikhah, A., Emadi, A., Dostdari, S.   +5 more
doaj  

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Mechanistic research holds promise for bacterial vaccines and phage therapies for Pseudomonas aeruginosa [PDF]

, 2019
Austin Hoggarth,1,* Andrew Weaver,1,* Qinqin Pu,1,* Ting Huang,1,2 Jacob Schettler,1 Feng Chen,3 Xiefang Yuan,3 Min Wu1 1Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA; 2Key ...
Pu Q, Weaver A, Schettler J, Wu M, Huang T, Chen F, Hoggarth A, Yuan X   +7 more
core  

Russian vaccines against especially dangerous bacterial pathogens [PDF]

, 2014
In response to the epidemiological situation, live attenuated or killed vaccines against anthrax, brucellosis, cholera, glanders, plague and tularemia were developed and used for immunization of at-risk populations in the Former Soviet Union.
Valentina A Feodorova, Lidiya V Sayapina, Vladimir L Motin, Michael J Corbel   +3 more
core   +1 more source

From Chatbots to Co‐Scientists: The Impact of Knowledge‐Generating AI (AI 4.0) on Healthcare and Research

Advanced Science, EarlyView.
This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

Hepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen, Yu‐Chia Su, Yee‐Ern Or, Chin‐Fu Cheng, John T. Kung   +4 more
wiley   +1 more source

ENGINEERING BACTERIAL GLYCOBIOLOGY FOR THE CREATION OF GLYCOCONJUGATE VACCINES [PDF]

, 2017
The use of vaccines has led to the effective eradication of several human diseases which were once epidemic such as smallpox and polio. Vaccines have also dramatically decreased the incidence of other diseases including rabies, mumps, and measles.
Stevenson, Taylor Currie
core   +1 more source

Putative correlates of protection against shigellosis assessing immunomarkers across responses to S. sonnei investigational vaccine

npj Vaccines
Shigella spp. are a leading bacterial cause of diarrhea. No widely licensed vaccines are available and there is no generally accepted correlate of protection. We tested a S.
Valentino Conti, Omar Rossi, Kristen A. Clarkson, Francesca Mancini, Usman N. Nakakana, Eleanna Sarakinou, Andrea Callegaro, Pietro Ferruzzi, Alessandra Acquaviva, Ashwani Kumar Arora, Elisa Marchetti, Francesca Necchi, Robert W. Frenck, Laura B. Martin, Robert W. Kaminski, Audino Podda, Francesca Micoli   +16 more
doaj   +1 more source