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The History, Present and Future of Allergen Standardization in the United States and Europe
Frontiers in Immunology, 2021 The topic of standardization in relation to allergen products has been discussed by allergists, regulators, and manufacturers for a long time. In contrast to synthetic medicinal products, the natural origin of allergen products makes the necessary ...
Julia Zimmer +5 more
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Tuberculosis vaccine: pipeline approaches and future prospective [PDF]
, 2011 Tuberculosis (TB), despite anti-mycobacterial therapies and vaccine, is a deadly infectious disease with about 12 million incident cases worldwide. Existing Bacillus Calmette-Guérin (BCG) vaccine is unquestionably inexpensive, safe and effective ...
Ankita Singh +2 more
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Ticks and Tick-Borne DiseasesLyme borreliosis (LB) is the most common vector-borne disease in Europe. At least 29 European Economic Area (EEA) countries publish online LB surveillance reports.
Alexander Davidson +6 more
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Development of Phage Lysin LysA2 for Use in Improved Purity Assays for Live Biotherapeutic Products
Viruses, 2015 Live biotherapeutic products (LBPs), commonly referred to as probiotics, are typically preparations of live bacteria, such as Lactobacillus and Bifidobacterium species that are considered normal human commensals.
Sheila M. Dreher-Lesnick +2 more
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Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs. [PDF]
, 2018 Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Gervay-Hague, Jacquelyn +2 more
core +1 more source
Vaccine implementation: Alaska 2017 [PDF]
, 2017 Bacterial meningitis is a serious disease that causes permanent dysfunction or death; adolescents and young adults carry the greatest risk. The national Advisory Committee on Immunization Practices (ACIP) has released vaccine recommendations that include
Hulstine, Amanda
core
Spirochetal Lipoproteins and Immune Evasion. [PDF]
, 2017 Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani +2 more
core +1 more source
A Vaccine Against Group B Streptococcus: Recent Advances [PDF]
, 2020 Group B streptococcus (GBS) causes a high burden of neonatal and infant disease globally. Implementing a vaccine for pregnant women is a promising strategy to prevent neonatal and infant GBS disease and has been identified as a priority by the World ...
Carreras-Abad, C +3 more
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A randomized phase 1/2a trial of ExPEC10V vaccine in adults with a history of UTI
npj VaccinesThe safety, reactogenicity, and immunogenicity of 3 doses of ExPEC10V (VAC52416), a vaccine candidate to prevent invasive Escherichia coli disease, were assessed in a phase 1/2a study (NCT03819049). In Cohort 1, ExPEC10V was well tolerated; the high dose
Carlos A. Fierro +9 more
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Polysaccharide Vaccines: A Perspective on Non-Typhoidal Salmonella
Polysaccharides, 2021 Polysaccharides are often the most abundant antigens found on the extracellular surfaces of bacterial cells. These polysaccharides play key roles in interactions with the outside world, and for many bacterial pathogens, they represent what is presented ...
Sumudu R. Perera +2 more
doaj +1 more source