Isolation, identification, and monitoring of antibiotic resistance in Pasteurella multocida and Mannheimia haemolytica isolated from sheep in East Azerbaijan province, Iran [PDF]
The present study was carried out in order to isolate, identify, and assess the antimicrobial susceptibility of the causative agent(s) of pneumonic pasteurellosis in sheep in East Azerbaijan province, northwest of Iran.
I. Khalili +6 more
doaj +1 more source
Bacterial Spores as Vaccine Vehicles [PDF]
ABSTRACT For the first time, bacterial spores have been evaluated as vaccine vehicles. Bacillus subtilis spores displaying the tetanus toxin fragment C (TTFC) antigen were used for oral and intranasal immunization and were shown to generate mucosal and systemic responses in a murine model.
DUC L. H. +4 more
openaire +3 more sources
Features of intellectual property protection mechanisms on the example of orphan drugs circulation
Objective: to study features of intellectual property protection mechanisms on the example of drugs for the treatment of rare (orphan) diseases.Material and methods.
D. S. Yurochkin +4 more
doaj +1 more source
Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines. [PDF]
Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a large scale and free of contaminating bacterial toxins and antigens.
G. C. Whitelam (7665758) +58 more
core +1 more source
New drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections [PDF]
Tuberculosis remains the most common cause of death due to a single infective organism. Despite the availability of a vaccine and chemotherapeutic options, the global disease burden remains relatively unaffected.
Willcox, Benjamin +12 more
core +1 more source
Q Fever Vaccine Development: Current Strategies and Future Considerations
Q fever is a zoonotic disease caused by the intracellular pathogen Coxiella burnetii. This disease typically manifests as a self-limiting, febrile illness known as acute Q fever.
Carrie Mae Long
doaj +1 more source
Changes in serogroup and genotype prevalence among carried meningococci in the United Kingdom during vaccine implementation [PDF]
Natural fluctuations in carried meningococcal genotypes and phenotypes a can be affected by the use of conjugate vaccines, and not all of these changes are anticipatable in advance of vaccine ...
McCarthy, Noel D. +83 more
core +1 more source
Development of vaccines against burkholderia pseudomallei. [PDF]
Burkholderia pseudomallei is a Gram-negative bacterium which is the causative agent of melioidosis, a disease which carries a high mortality and morbidity rate in endemic areas of South East Asia and Northern Australia.
Patel, Natasha +23 more
core +1 more source
A human Lyme disease vaccine: two steps forward on the path to prevention
Introduction Lyme disease is caused by the tick-borne spirochete pathogen Borrelia burgdorferi sensu lato (s.l.). Outer surface protein A (OspA) is expressed by B. burgdorferi s.l.
Raphael Simon +3 more
doaj +1 more source
Bacterial outer membrane vesicles and vaccine applications
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Jose Luis Perez +30 more
core +1 more source

