Results 21 to 30 of about 129,985 (296)

Characterization of Lactobacilli Phage Endolysins and Their Functional Domains–Potential Live Biotherapeutic Testing Reagents

open access: yesViruses, 2023
Phage endolysin-specific binding characteristics and killing activity support their potential use in biotechnological applications, including potency and purity testing of live biotherapeutic products (LBPs).
Robert J. Dorosky   +5 more
doaj   +1 more source

Vaccines against human enteric bacterial pathogens [PDF]

open access: yes, 2002
The development of vaccines against enteric bacterial pathogens presents a challenge because of the large number of pathogens capable of causing disease and the requirement to induce immunity that is effective in the gut.
Huett, Alan   +2 more
core   +1 more source

Virus-like Particle Vaccines and Platforms for Vaccine Development [PDF]

open access: yes, 2023
Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human papillomavirus, and hepatitis E virus—has been approved ...
Hong Liu   +2 more
core   +1 more source

Dose-specific efficacy of Haemophilus influenzae type b conjugate vaccines: a systematic review and meta-analysis of controlled clinical trials. [PDF]

open access: yes, 2012
Global coverage of infant Haemophilus influenzae type b (Hib) vaccination has increased considerably during the past decade, partly due to GAVI Alliance donations of the vaccine to low-income countries. In settings where large numbers of children receive
Clark, A   +6 more
core   +1 more source

Vaccines against bacterial meningitis [PDF]

open access: yesBritish Medical Bulletin, 2004
Meningitis remains an important cause of morbidity and mortality among children >5 years of age and is especially prevalent in developing countries. Effective routine immunization against Hib, pneumococcus and serogroupC meningococcus has had a significant impact on both invasive disease and carriage caused by these encapsulated bacteria.
Segal, S, Pollard, A
openaire   +3 more sources

Biological safety concepts of genetically modified live bacterial vaccines [PDF]

open access: yes, 2007
Live vaccines possess the advantage of having access to induce cell-mediated and antibody-mediated immunity; thus in certain cases they are able to prevent infection, and not only disease. Furthermore, live vaccines, particularly bacterial live vaccines,
Frey, Joachim
core   +1 more source

Analysis of pneumococcal serotypes distribution to determine a model composition for a Russian pneumococcal conjugate vaccine

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2022
Diseases caused by Streptococcus pneumoniae, as well as antibiotic resistance of its serotypes, are the leading cause of death amongst children worldwide.
V. P. Trukhin   +5 more
doaj   +1 more source

REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF DOMESTIC FLU-M INACTIVATED SPLIT INFLUENZA VACCINE FOR THE IMMUNIZATION OF ADULTS AGED BETWEEN 18 AND 60

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. The research was aimed at evaluating the reactogenicity, safety and immunogenicity of Flu-M inactivated split influenza vaccine. Materials and methods.
I. V. Feldblyum   +11 more
doaj   +1 more source

Efficacy, safety, and immunogenicity of the Shigella sonnei 1790GAHB GMMA candidate vaccine: Results from a phase 2b randomized, placebo-controlled challenge study in adults

open access: yesEClinicalMedicine, 2021
Background: Shigellosis accounts for substantial morbidity and mortality worldwide and is the second most common cause of moderate and severe diarrhoea in children.
Robert W. Frenck, Jr   +23 more
doaj   +1 more source

Bacterial Spores as Vaccine Vehicles [PDF]

open access: yesInfection and Immunity, 2003
ABSTRACT For the first time, bacterial spores have been evaluated as vaccine vehicles. Bacillus subtilis spores displaying the tetanus toxin fragment C (TTFC) antigen were used for oral and intranasal immunization and were shown to generate mucosal and systemic responses in a murine model.
DUC L. H.   +4 more
openaire   +3 more sources

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