Results 21 to 30 of about 1,154,986 (294)

Clinical trial of tolerability, safety, and immunogenicity of the Russian influenza inactivated split vaccine Flu-m in children from 6 months to 9 years of age

Журнал инфектологии, 2023
Purpose: To study the reactogenicity, safety and immunogenicity of the Russian vaccine Flu-M in comparison with Vaxigrip vaccine for influenza prevention in children aged from 6 months to 9 years (phase III).Materials and Methods.
A. M. Korolyuk, L. A. Zazimko, V. N. Kraeva, Yu. A. Koromzin, E. A. Ruzanova, A. A. Ekimov, N. N. Savina, E. V. Ryskova, V. P. Trukhin   +8 more
doaj   +1 more source

Adjuvants : an essential component of neisseria vaccines [PDF]

, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R., del Campo, J., Zayas, C., Cuello, M., Romeu, B., Ferro, Valerie A., Gonzales, E., Cabrera, O., Balbao, J.   +8 more
core   +4 more sources

IMMUNOGENICITY OUTCOMES OF A RANDOMIZED, MULTICENTER, INTERVENTIONAL, FIRST-IN-HUMAN, PHASE 1/2A STUDY OF VAC52416 (EXPEC10V), A VACCINE CANDIDATE FOR THE PREVENTION OF INVASIVE ESCHERICHIA COLI DISEASE

International Journal of Infectious Diseases, 2023
Intro: The safety, reactogenicity, and immunogenicity of VAC52416 (ExPEC10V), a vaccine candidate to prevent invasive Escherichia coli disease, was assessed in a phase 1/2a study (NCT03819049). Results from Cohort 1 have been presented. Here, we describe
C. Fierro, M. Sarnecki, J. Doua, B. Spiessens, O. Go, T. Davies, G. van den Dobbelsteen, J. Poolman, D. Abbanat, W. Haazen   +9 more
doaj   +1 more source

Glyceraldehyde-3-phosphate dehydrogenase common peptides of listeria monocytogenes, mycobacterium marinum and streptococcus pneumoniae as universal vaccines [PDF]

, 2021
Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera Listeria, Mycobacterium and ...
Del Molino-Bernal, I. Concepción Pérez, Torres-Rodriguez, Paula, Calvo-Montes, Jorge, David Salcines-Cuevas, Pérez Del Molino-Bernal, Concepción, Ricardo Calderón-Gonzalez, Manuel Fresno, Álvarez-Domínguez, Carmen, Teran-Navarro, Héctor, Fresno, Manuel, Raquel Tobes, Molino-Bernal, I Concepción Pérez Del, Paula Torres-Rodriguez, Carmen Alvarez-Dominguez, I. Concepción Pérez Del Molino-Bernal, Salcines-Cuevas, David, Fresno Escudero, Manuel, Pérez Del Molino Bernal, I. Concepción, Hector Terán-Navarro, Yañez-Diaz, Sonsoles, Jorge Calvo-Montes, Sonsoles Yañez-Diaz, Calderón-González, Ricardo, Tobes, Raquel   +23 more
core   +1 more source

Chikungunya vaccines: advances in the development and prospects for marketing approval

Биопрепараты: Профилактика, диагностика, лечение, 2023
Chikungunya fever is an acute infectious disease caused by the mosquito-borne Chikungunya virus (CHIKV). In the last decades, cases of the disease have been reported in more than 100 countries; therefore, CHIKV presents a global public health problem ...
E. V. Otrasheuskaja, V. P. Trukhin, V. A. Merkulov, G. M. Ignatyev   +3 more
doaj   +1 more source

Composing of an oil adjuvant containing BCG as an immunomodulating for rabbit clostridial enterotoxaemia and bloat vaccine [PDF]

Veterinary Medical Journal - Giza, 2022
Clostridium perfringens (C. perfringens) is one of the most important pathogen that is widely distributed in all over the world and responsible for many diseases among life stock.
Hamed ElHelw, Shereen Fouad, Marwah Mohamed, Gina Mohammed, Alaa ElKholy   +4 more
doaj   +1 more source

High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis

Microbial Cell Factories, 2018
Background Outer membrane vesicles (OMVs) are nanoparticles released by Gram-negative bacteria and can be used as vaccines. Often, detergents are used to promote release of OMVs and to remove the toxic lipopolysaccharides.
Matthias J. H. Gerritzen, Ronald H. W. Maas, Jan van den Ijssel, Lonneke van Keulen, Dirk E. Martens, René H. Wijffels, Michiel Stork   +6 more
doaj   +1 more source

Development of Streptococcus pneumoniae Vaccines Using Live Vectors [PDF]

, 2015
: Streptococcus pneumoniae still causes severe morbidity and mortality worldwide, especially in young children and the elderly. Much effort has been dedicated to developing protein-based universal vaccines to conquer the current shortcomings of capsular ...

core   +1 more source

Characterization of Lactobacilli Phage Endolysins and Their Functional Domains–Potential Live Biotherapeutic Testing Reagents

Viruses, 2023
Phage endolysin-specific binding characteristics and killing activity support their potential use in biotechnological applications, including potency and purity testing of live biotherapeutic products (LBPs).
Robert J. Dorosky, Stephanie L. Lola, Haleigh A. Brown, Jeremy E. Schreier, Sheila M. Dreher-Lesnick, Scott Stibitz   +5 more
doaj   +1 more source

Low-Energy Electron Irradiation (LEEI) for the Generation of Inactivated Bacterial Vaccines

, 2021
S.97-113Vaccines consisting of whole inactivated bacteria (bacterins) are generated by incubation of the pathogen with chemicals. This is a time-consuming procedure which may lead to less immunogenic material, as critical antigenic structures can be ...
Sebastian Ulbert, Bastian Standfest, Thomas Grunwald, Grunwald, Thomas, Jana Beckmann, Ulbert, Sebastian, Martin Thoma, Fertey, Jasmin, Standfest, Bastian, Beckmann, Jana, Jasmin Fertey, Thoma, Martin   +11 more
core   +1 more source