Results 211 to 220 of about 233,740 (307)

Predicted microbiome‐associated metabolic pathways are linked to immune checkpoint modulation in chronic lymphocytic leukaemia

British Journal of Haematology, EarlyView.
Summary Microbial metabolites are key regulators of host immunity, yet their functional impact in chronic lymphocytic leukaemia (CLL) remains unclear. Following up on our earlier observations of microbiome dysbiosis in CLL, we performed predictive metabolic profiling based on 16S ribosomal RNA (rRNA) sequencing of oral and stool samples collected from ...
Monika Szelest, Joanna Zaleska, Michał Kiełbus, Magdalena Paziewska, Marta Masternak, Ewa Wawrzyniak, Aleksandra Kotkowska, Monika Siemieniuk‐Ryś, Marta Morawska, Elżbieta Kalicińska, Paula Jabłonowska‐Babij, Tomasz Wróbel, Anna Wolska‐Washer, Jerzy Zdzisław Błoński, Tadeusz Robak, Krzysztof Giannopoulos   +15 more
wiley   +1 more source

Progress and promise of CAR-T cell treatment in autoimmune diseases. [PDF]

PLoS Med
Bachl J, Hagen M, Schett G.
europepmc   +1 more source

Multi-dimensional orchestration of binders for improved CAR-T immunotherapy. [PDF]

Cancer Lett
Zhu C, Jiang Z, Jing R, Guo W, Lu Y.
europepmc   +1 more source

A multimodal viro-immunotherapy strategy for glioblastoma. [PDF]

Mol Ther Oncol
Li J, Shi Y.
europepmc   +1 more source

Circulating Extracellular Vesicle Biomarkers in Chronic Lymphocytic Leukemia: A Preliminary Study on Their Diagnostic, Prognostic, and Predictive Relevance. [PDF]

Biomolecules
Laurenzana I, Caivano A, Di Ciancia A, Villani O, Maietti M, De Stradis A, D'Arena G, Nozza F, De Luca L, Lamorte D.   +9 more
europepmc   +1 more source

Protein Corona‐Coated Crystal Silica From Sandstorms Amplifies Allergic Rhinitis by Regulating Epithelial Integrity in Mice and Human Nasal Epithelia

Allergy, EarlyView.
Cuishuang Dong, Xu Zhang, Haoyue Wang, Jiajing Cui, Shuai Han, Yibo Wang, Huanying Zhao, Yang Song, Yuan Zhang, Xiaobo Li   +9 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

CD19 expression is preserved following CD19-directed monoclonal antibody therapy with tafasitamab. [PDF]

Front Immunol
Duell J, Alvarez Arias D, Klapper W, Reinke S, Eisele F, Larsen TS, Topp MS, Rumberger B, Kim T, Rosenwald A, Rauert-Wunderlich H.   +10 more
europepmc   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Selective decreases in regulatory B-cell (Breg) subsets in active uveitis: IL-10+CD19+CD24hiCD38hiBregs in patients and B10 Bregs in mice. [PDF]

Int Immunol
Chen YH, Zhang X, Eskandarpour M, Gilbert RM, Lightman S, Calder VL.   +5 more
europepmc   +1 more source