Results 21 to 30 of about 233,497 (306)

Efficacy of Dual Cd19-Cd79B Car In B-Cell Malignancies [PDF]

, 2022
Despite high clinical responses, about 30%-60% of patients with B-cell malignancies relapse following CD19-targeting chimeric antigen receptor (CAR) T cell therapy. CD19 loss is a major cause of relapse and resistance after CD19 CAR T therapy.
Cheng, Xiaoyun
core   +1 more source

Acute myeloid leukemia: Comparing French–American–British classification with immunophenotype and cytogenetics

BLDE University Journal of Health Sciences, 2022
BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease as it affects multiple lineages of hematopoietic cells. AIMS AND OBJECTIVES: This study aims to (1) evaluate the immunophenotypic findings of AML patients, (2) correlate the ...
Mekhala Rao, Girish Kamat, Deepak Goni, Girish Balikai   +3 more
doaj   +1 more source

Immunity to Intracellular Salmonella Depends on Surface-associated Antigens [PDF]

, 2012
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum.
Rizos Konstantin, Beatrice Claudi (126116), Dirk Bumann (126124), Dirk Bumann, Somedutta Barat (126107), Barat, Somedutta, Rizos, K., Bumann, D., Schemmer, Anne K, Claudi Beatrice, Neil Burton (126123), Anne K Schemmer, Barat Somedutta, Dennis Kirchhoff (126121), Somedutta Barat, Alexander Schmidt (68515), Kirchhoff, D., Alain Mazé, Willer, Yvonne, Anne K. Schemmer (126119), Kirchhoff Dennis, Rizos, Konstantin, Dennis Kirchhoff, Bumann, Dirk, Burton Neil, Schemmer, A., Claudi, B., Mazé, Alain, Schmidt Alexander, Schemmer Anne K., Yvonne Willer (126110), Konstantin Rizos (126113), Willer Yvonne, Yvonne Willer, Willer, Y., Burton, Neil, Bumann Dirk, Alexander Schmidt, Mazé Alain, Beatrice Claudi, Schmidt, A., Alain Mazé (126117), Mazé, A., Claudi, Beatrice, Kirchhoff, Dennis, Barat, S., Konstantin Rizos, Burton, N., Schemmer, Anne K., Schmidt, Alexander, Neil Burton   +50 more
core   +2 more sources

Different expression of CD180, CD284 and CD14 receptors on the CD19+ subpopulation of normal and B-CLL lymphocytes.

Folia Histochemica et Cytobiologica, 2010
Numerous experimental data indicate that B-CLL development and progression are influenced by antigenic pressure. It can not be excluded that these antigens may originate from bacteria and viruses.
Barbara Marzec-Kotarska, Joanna Sajewicz, Halina Antosz, Janusz Kocki, Anna Dmoszyńska   +4 more
doaj   +1 more source

Unifying heterogeneous expression data to predict targets for CAR-T cell therapy

OncoImmunology, 2021
Chimeric antigen receptor (CAR) T-cell therapy combines antigen-specific properties of monoclonal antibodies with the lytic capacity of T cells. An effective and safe CAR-T cell therapy strategy relies on identifying an antigen that has high expression ...
Patrick Schreiner, Mireya Paulina Velasquez, Stephen Gottschalk, Jinghui Zhang, Yiping Fan   +4 more
doaj   +1 more source

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies.
Webb, Emily L, Emily L Webb, Dunne, David W, Dunne, David W., Tweyongyere, Robert, Mawa, Patrice A, Birgitte J Vennervald, David W Dunne, Jones, Frances M., Webb, Emily L., Elliott, Alison M., Patrice A Mawa, Vennervald, Birgitte J, Frances M Jones, Stephen Cose, Kihembo, Macklyn, Alison M Elliott, Cose, Stephen, Macklyn Kihembo, Elliott, Alison M, Robert Tweyongyere, Jones, Frances M, Mawa, Patrice A.   +22 more
core   +6 more sources

Boosting antibody responses to Plasmodium falciparum merozoite antigens in children with highly seasonal exposure to infection. [PDF]

, 2010
Longitudinal cohort studies are important to describe the dynamics of naturally acquired antibody response profiles to defined Plasmodium falciparum malaria antigens relative to clinical malaria episodes.
M. PINDER, Dunyo, S, Conway, DJ, O. J. AKPOGHENETA, D. J. CONWAY, Akpogheneta, OJ, Pinder, M, S. DUNYO   +7 more
core   +1 more source

Distinct and shared B cell responses of tuberculosis patients and their household contacts

PLoS ONE, 2022
This study was aimed at identifying the B cell responses which could distinguish between ‘latent tuberculosis infection (LTBI)’ and active TB disease. Study subjects were smear-positive TB patients (n = 54) and their disease-free household contacts (HHCs,
Komal Singh, Rajesh Kumar, Fareha Umam, Prerna Kapoor, Sudhir Sinha, Amita Aggarwal   +5 more
doaj  

CAR-tropic extracellular vesicles carry tumor-associated antigens and modulate CAR T cell functionality

Scientific Reports, 2023
Tumor-derived extracellular vesicles (EVs) are active contributors in metastasis and immunosuppression in tumor microenvironment. At least some of the EVs carry tumor surface molecules such as tumor-associated antigens (TAAs) and/or checkpoint inhibitors,
V. M. Ukrainskaya, O. E. Musatova, D. V. Volkov, D. S. Osipova, D. S. Pershin, A. M. Moysenovich, E. G. Evtushenko, E. A. Kulakovskaya, E. G. Maksimov, H. Zhang, Y. P. Rubtsov, M. A. Maschan, A. V. Stepanov, A. G. Gabibov   +13 more
doaj   +1 more source

Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides

Journal of Immunology Research, 2015
We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study.
Serkan Yazıcı, Emel Bülbül Başkan, Ferah Budak, Barbaros Oral, Şaduman Balaban Adim, Zübeyde Ceylan Kalin, Güven Özkaya, Kenan Aydoğan, Hayriye Saricaoğlu, Şükran Tunali   +9 more
doaj   +1 more source