Results 231 to 240 of about 1,141,456 (326)

Diabetic Kidney Disease Progression Alleviated in Mice by ALKBH5‐Mediated UC‐MSCs‐Derived Exosomes That Inhibit TRAF6 m6A Modification and Promote M2 Macrophage Polarisation

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
ALKBH5‐modified UC‐MSCs‐derived exosomes (OE‐ALKBH5 Exo) inhibit the expression of M1 markers (iNOS, IL‐1β, TNF‐α, CD86) and enhance the expression of M2 markers (IL‐10, Arg‐1, CD206) by inhibiting the m6A methylation of TRAF6 and reducing its protein level and stability, thereby promoting M2 polarisation and alleviating the progression of DKD ...
Lei Li, Hongmei Liu, Huanhuan Wang, Yu Mao, Lige Song, Zhiqiang Kang   +5 more
wiley   +1 more source

A Transcriptional Map of Human Tonsil Architecture: Beyond the Sum of (Single Cell) Parts

European Journal of Immunology, Volume 56, Issue 1, January 2026.
Picture‐book compartmentalization makes tonsillar tissue an ideal model to study spatial immunology. Using single‐molecule imaging (SMI) of whole‐tissue sections, we showcase many an alternative view on tissue composition and architecture that these data and concomitant analyses provide—at the level of single cells, cellular neighborhoods, and ...
Helena L. Crowell, Laura Llaó‐Cid, Gerard Frigola, Samuel Gunz, Irene Ruano, Patricia Lorden, Max Ruiz, Marta Kulis, José Ignacio Martin‐Subero, Holger Heyn, Elias Campo, Anna Pascual‐Reguant   +11 more
wiley   +1 more source

The Flow Cytometric Evaluation of B- and T-Lymphoblastic Leukemia/Lymphoma. [PDF]

Cancers (Basel)
Dorfman DM.
europepmc   +1 more source

Das CD34- und CD45-Antigen als Detektionsparameter für die durchflußzytometrische Analyse [PDF]

Transfusion Medicine and Hemotherapy, 1996
openaire   +1 more source

Drivers of clinical resistance to venetoclax and hypomethylating agents in acute myeloid leukemia and strategies for improving efficacy

HemaSphere, Volume 10, Issue 1, January 2026.
ABSTRACT The B‐cell lymphoma 2 (BCL‐2) inhibitor venetoclax (VEN) in combination with hypomethylating agents (HMAs) has improved treatment outcomes for acute myeloid leukemia (AML) patients unfit for intensive chemotherapy and is increasingly used in the relapsed/refractory setting. However, primary resistance remains a significant challenge, affecting
Ida Vänttinen, Joseph Saad, Tanja Ruokoranta, Sari Kytölä, Guangrong Qin, Bahar Tercan, Pia Ettala, Anu Partanen, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Mikko Manninen, Peter J. M. Valk, Gerwin Huls, Vésteinn Thorsson, Caroline A. Heckman, Mika Kontro, Heikki Kuusanmäki   +17 more
wiley   +1 more source

Targeting the N-cadherin/<i>β</i>-catenin axis with MSAB reverses malignant phenotypes in blast crisis of CML. [PDF]

Front Oncol
Zhou Y, Jian S, Lu L, Li X, Qiu R.
europepmc   +1 more source

Rps19R67∆ mutation creates a model of Diamond–Blackfan anemia and reveals downstream mediators of p53 pathway

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosomal proteins, including RPS19, a component of the 40S ribosomal subunit.
Juraj Kokavec, Tereza Turková, Björn Schuster, Jan Prochazka, František Spoutil, Kristína Jamrichová, Markéta Holečková, Karel Chalupský, Inken M. Beck, Jesús Ruberte, Matilde Vale, Lukáš Čermák, Tomáš Stopka, Radislav Sedlacek   +13 more
wiley   +1 more source

Potency of human hematopoietic cells from a novel CD34+ isolation technique. [PDF]

Stem Cells Transl Med
Ropa J, Park J, Newton J, Kim SJ, Park Y, Messer J, Blacher J, Namin S.   +7 more
europepmc   +1 more source

Angiogenic Potential of Small Extracellular Vesicles Produced by Stimulated Mesenchymal Stromal Cells Under Hypoxic Conditions

Journal of Extracellular Biology, Volume 5, Issue 1, January 2026.
ABSTRACT Regenerative vascular medicine research has positioned mesenchymal stromal cells (MSCs) as a leading candidate to treat ischemic diseases. Recent studies have highlighted the emerging role of small extracellular vesicles (sEVs) produced by MSCs in their own potential.
Nada Serhal, Bertrand Brassart, Lise Nannan, Sandra Audonnet, Christine Terryn, Gaël Poitevin, Pascale Cornillet‐Lefebvre, Florine Dubuisson, Hélène Peyret, Philippe Nguyen, Claire Tournois   +10 more
wiley   +1 more source

State of the Art of CAR-NK Cell Therapy in Multiple Myeloma: A Comprehensive Review of Cell Sources and Target Antigens. [PDF]

Int J Mol Sci
Bastrich A, Vinogradova K, Mokrousova D, Efremova A, Makhnach O, Goldshtein D.   +5 more
europepmc   +1 more source