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The CD34 antigen: Potential clinical advantages of CD34 selection

Clinical Oncology, 1996
The availability of monoclonal antibodies directed towards the haemopoietic cell surface antigen CD34 has facilitated accurate measurement, by flow cytometry, of CD34 positive cell frequencies in bone marrow and peripheral blood. In addition, a range of CD34 selection techniques, to purify peripheral blood progenitor cells or bone marrow prior to ...
T L, Holyoake   +2 more
openaire   +2 more sources

Expression of CD34-antigen in nasopharyngeal angiofibromas

International Journal of Pediatric Otorhinolaryngology, 1998
Formalin-fixed, paraffin-embedded and frozen tissues of 24 patients with primary nasopharyngeal angiofibroma, of whom seven had recurrences, were studied immunohistochemically for the expression of CD34 antigen using two different antibodies (HPCA-1 and QBEND 10).
A, Beham   +4 more
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Expression of the CD34 antigen in pleomorphic xanthoastrocytomas

Acta Neuropathologica, 2002
Pleomorphic xanthoastrocytoma (PXA) is a rare, superficially located astrocytic glioma of children and young adults, which is associated with a relatively favorable prognosis. Here we report on the expression of the hematopoietic progenitor cell and vascular endothelial cell associated antigen CD34 in PXAs.
G, Reifenberger   +3 more
openaire   +2 more sources

Immunohistochemical investigation of CD34 antigen in male breast carcinoma

Clinical and Experimental Medicine, 2007
A total of 30 archival cases of male breast carcinoma were studied immunohistochemically for the expression of CD34 antigen. An obvious CD34 staining was found in three cases. By adding the original CD34-positive case, recently published as unique CD34-stained male breast carcinoma, the number of positive cases comes to four.
S, Milias   +7 more
openaire   +2 more sources

The CD34 Antigen: Structure, Biology, and Potential Clinical Applications

Journal of Hematotherapy, 1992
The diversity of function of mature circulating blood cells is reflected in their respective complements of cell-surface molecules and receptors. Although monoclonal antibodies have been instrumental in the identification and characterization of many cell-surface molecules on mature hematopoietic cells, the CD34 antigen represents to date, the only ...
D R, Sutherland, A, Keating
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Expression of CD34 antigen in testicular mixed germ cell tumor

Pathology International, 2003
The expression of CD34 was investigated in 14 cases of testicular mixed germ cell tumor to elucidate the relationship between its expression and histological patterns. Seven of 12 yolk sac tumor components were focally immunoreactive for anti‐CD34 antibody.
Shuji, Hamazaki, Shigeru, Okada
openaire   +2 more sources

Hematopoietic Stem Cell Antigen CD34: Role in Adhesion or Homing

Stem Cells and Development, 2006
CD34 is highly glycosylated surface antigen of enormous clinical utility in the identification, enumeration, and purification of engraftable lymphohematopoietic progenitors for transplantation. However, recently its importance in the specific marking of most immature hematopoietic stem/progenitor cells have been questioned by addressing long-term ...
Gurudutta U, Gangenahalli   +6 more
openaire   +2 more sources

Significance of hematopoietic surface antigen CD34 in neuroblastoma prognosis and the genetic landscape of CD34-expressing neuroblastoma CSCs

Cell Biology and Toxicology, 2020
High-risk neuroblastoma (HR-NB) is branded with hematogenous metastasis, relapses, and dismal long-term survival. Intensification of consolidation therapy with tandem/triple autologous stem cell (SC) rescue (with bone marrow [BM]/peripheral blood [PB] CD34+ selection) after myeloablative chemotherapy has improved long-term survival.
Natarajan Aravindan   +3 more
openaire   +2 more sources

Novel transcription factors in human CD34 antigen–positive hematopoietic cells

Blood, 2002
AbstractTranscription factors (TFs) and the regulatory proteins that control them play key roles in hematopoiesis, controlling basic processes of cell growth and differentiation; disruption of these processes may lead to leukemogenesis. Here we attempt to identify functionally novel and partially characterized TFs/regulatory proteins that are expressed
Ignatius, Gomes   +5 more
openaire   +2 more sources

Separation of CD34 positive cells and determinationof surface homing antigen

Current Medical Science, 2000
To study the differences in homing potential between bone marrow cells and umbilical blood cells, CD34 positive cells were obtained from bone marrow (BM) and umbilical blood (UB) by the direct cell separation with domestic immunomagnetic beads. The expression of the two adhesion molecules CD11a/CD18 and CD44 were examined.
L, Wang, P, Zou, Y, You
openaire   +2 more sources

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