Results 251 to 260 of about 1,141,456 (326)

Dynamic Regulation of Collagens, Proteases, Their Inhibitors, and Cell Death in Experimental Asthma in Mice

Allergy, Volume 81, Issue 1, Page 170-184, January 2026.
This study investigates airway remodeling in acute and chronic experimental asthma models induced by house dust mite extract to elucidate inflammatory and structural changes. Two acute T2‐low models demonstrated pronounced airway inflammation characterized by goblet cell hyperplasia, collagen deposition, and significant upregulation of extracellular ...
Marlena Tynecka, Agnieszka Tarasik, Bartosz Hanczaruk, Adrian Janucik, Krystian Czolpinski, Alicja Walewska, Arkadiusz Zbikowski, Anna Zeller, Agnieszka Kulczynska‐Przybik, Magdalena Niemira, Joanna Reszec‐Gielazyn, Barbara Mroczko, Adam Kretowski, Cezmi A. Akdis, Milena Sokolowska, Marcin Moniuszko, Cagatay Karaaslan, Andrzej Eljaszewicz   +17 more
wiley   +1 more source

Laminar CD34+ membranous cells with mechanosensitive properties in subcutaneous fascia of the abdominal midline. [PDF]

Sci Rep
Huang H, Mei L, Zhang Z, Yue J, Dai M, Lu L, Yang M, Fan L, Yang T, Chen Q.   +9 more
europepmc   +1 more source

Hemangioblastoma of the Kidney—A Comprehensive Clinical, Pathological, and Genetic Analysis of Four Cases

APMIS, Volume 134, Issue 1, January 2026.
ABSTRACT Hemangioblastoma (HB) is a benign central nervous system (CNS) tumor associated with mutations in the von Hippel–Lindau (VHL) gene. Although rare outside the CNS, the pathological and genetic features remain poorly understood. We analyzed four renal hemangioblastomas (RHB). Demographics, clinical presentation, and follow‐up data were collected.
Boglárka Pósfai, Alex Jenei, Gertrúd Forika, Attila Fintha, Zoltán Sápi, Áron Somorácz, Borbála Dénes, Ferenc Salamon, Kornélia Veronika Eizler, Nándor Giba, Dávid Semjén, Ildikó Illyés, Kristóf Attila Kovács, Gyöngyi Munkácsy, János Papp, Fanni Sánta, Henriett Butz, Levente Kuthi   +17 more
wiley   +1 more source

SMARCA4‐Deficient Undifferentiated Thoracic Tumor: Clinical Features and Prognosis of a Case Series and Literature Review

The Clinical Respiratory Journal, Volume 20, Issue 1, January 2026.
Our manuscript presents detailed presentations of case series of thoracic SMARCA4‐UT, and we report a unique case of diaphragmatic metastases and, interestingly, the occurrence of brain metastasis in one patient, which is a rare phenomenon in SMARCA4‐UT.
Fangzhen Shan, Shuntao Liang, Youwen Zhang, Wei Wu, Guangxia Yang, Mei Yan, Xuemei Zhang, Yumao Miao, Linlin Liu, Jingjing Cai, Zhitao Shi, Bangdong Liu, Nannan Zhang   +12 more
wiley   +1 more source

Effect of Exposure to Room Temperature During Storage on Cryopreserved Umbilical Cord Blood Quality. [PDF]

Ann Lab Med
Kim K, Kang MS, Huh J.
europepmc   +1 more source

Toll‐Like Receptor Polymorphisms Influence Graft‐Versus‐Host Disease and Infection Risk After Single‐Unit Cord Blood Transplantation for Adults

European Journal of Haematology, Volume 116, Issue 1, Page 37-45, January 2026.
ABSTRACT Background Toll‐like receptors (TLRs) play a critical role in innate immunity by recognizing pathogen‐associated and damage‐associated molecular patterns. Genetic polymorphisms in TLR genes can modulate immune responses and have been implicated in the outcomes of allogeneic hematopoietic cell transplantation (HCT).
Takaaki Konuma, Megumi Hamatani‐Asakura, Seiko Kato, Shohei Andoh, Hirona Ichimura, Junichi Kuroda, Kaori Kondo, Kazuaki Yokoyama, Maki Monna‐Oiwa, Yasuhito Nannya, Satoshi Takahashi   +10 more
wiley   +1 more source

Positive influence of long-term growth hormone therapy on circulating stem cells in pediatric patients with growth hormone deficiency. [PDF]

Sci Rep
Wędrychowicz A, Sielatycka K, Kucia M, Kubiś E, Roztoczyńska D, Starzyk JB.   +5 more
europepmc   +1 more source

Dendritic Cells in the Gastrointestinal System: Division of Labor, Plasticity, and Niche‐Specific Adaptation

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT The intestinal immune system is constantly challenged to distinguish between innocuous dietary antigens, commensal microbiota and intestinal self‐antigens (self‐Ags) versus harmful pathogens and malignant cells. It resides in the intestinal wall itself, Peyer's patches (PPs) and the draining lymph nodes (LNs).
Yixuan D. Zhou, Macy R. Komnick, Daria Esterházy   +2 more
wiley   +1 more source

Functional classification of platelet gene variants using CRISPR HDR in CD34⁺ cell-derived megakaryocytes. [PDF]

Am J Hum Genet
Kosaka Y, Lopez B, Kishimoto N, Jacob S, Montenont E, Huallanca R, Coughenour G, Di Paola J, Ross J, Lee K, Rondina MT, Bray PF, Rowley JW.   +12 more
europepmc   +1 more source

Chimeric Antigen Receptor T‐Cell Therapy: More Than an Anti‐Cancer Drug

HLA, Volume 107, Issue 1, January 2026.
ABSTRACT Initially, chimeric antigen receptor (CAR) T‐cell therapy was developed to eliminate malignant B cells in haematological B‐cell malignancies by targeting CD19 and B‐cell maturation antigen. This approach achieved notable success, resulting in (malignant) B‐cell depletion and inducing clinical remission in cancer patients.
Hannah C. M. Schenk, Ilse Gille, Carolt Arana, Jordi Rovira, Eduard Palou, Fritz Diekmann, Dave L. Roelen, Mirjam H. M. Heemskerk, Sebastiaan Heidt   +8 more
wiley   +1 more source