Electron microscopy demonstration of CD34 antigen on progenitor pseudopodia
Experimental Hematology, 2000Abstract Current theory predicts stem cells are CD34-negative, despite CD34 use for therapeutic progenitor purification. Expressed on early haemopoietic cells, it is implicated in cellular adhesion, and marrow stromal cell homing. There are 2 CD34 forms, one intracellularly truncated, hypothesised for adhesion alone, with the extended variant capable ...
C. Hayward-Costa +6 more
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The Prognostic Significance of the CD34 Antigen in Acute Myeloid Leukaemia
Leukemia & Lymphoma, 1992The prognostic value of CD34 expression on leukaemic blast cells was assessed in 38 patients with acute myeloid leukaemia. Nineteen patients had more than 10% CD34 positive blast cells. Median survival for the CD34 positive patients was 125 days and for the CD34 negative patients the median survival has not yet been reached at day 575 (p = 0.06).
H, Myint, N P, Lucie
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The expression of the endothelial cell antigen CD34 in demyelinating disease
Neuropathology and Applied Neurobiology, 1996In this study, the antigenic expression of CD34, a 110 kDa glycoprotein which is expressed on human haemopoletic cells and vascular endothelium, has been assessed in variety of neuropathological conditions, including infectious and demyelinating disease.
I V, Allen +4 more
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Decreased Expression of the Human Progenitor Cell Antigen (CD34) in Morphea
The American Journal of Dermatopathology, 1995Morphea is an idiopathic disorder the hallmark of which is fibrosis of the skin. The regulatory factors resulting in the increased collagen production have not been determined. Within the dermis there are dendritic cells with possible immunological functions that express either the human progenitor cell antigen (CD34) or factor XIIIa ...
K, Skobieranda, K F, Helm
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Small cell lung cancer can express CD34 antigen.
Anticancer research, 1998In humans CD34 is a valid and reliable marker for hematopoletic stem and progenitor cells. In general, solid tumors, with the exception of endothelial cancers, do not express CD34. Accordingly, immunological selection of CD34+ hematopoietic stem/progenitor cells can be used to remove CD34- malignant cells in the setting of autotransplantation.
H, Yamane +8 more
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CD34 antigen expression of acute myeloid leukemia-colony forming cells
The International Journal of Cell Cloning, 1992Hematopoietic The International Journal of Cell Cloning express the CD34 antigen on their surface. Their proportion in a harvest can provide a quick and reliable measure of the hemopoietic efficiency of the harvest. In ANLL a variable proportion of blast cells express the same antigen: the aim of our study was to investigate whether clonogenic ANLL ...
F. Silvestri +7 more
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Angiogenesis in the human temporomandibular joint studied by immunohistochemistry for CD34 antigen
Journal of Oral Pathology & Medicine, 1999The CD34 antigen is a sensitive marker of vascular endothelium and angiogenesis. Thus, we examined the expression of CD34 in 20 human temporomandibular joint (TMJ) samples with internal derangement and in 10 control specimens by an immunohistological technique using paraffin‐embedded tissue and specific anti‐human CD34 monoclonal antibody.
H, Yoshida +3 more
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Immunoreactivity for the Human Hematopoietic Progenitor Cell Antigen (CD34) in Lipomatous Tumors
The American Journal of Surgical Pathology, 1997The human hematopoietic progenitor cell antigen (CD34) recently was shown to react with a variety of nonhematopoietic tissues and their tumors, including vascular endothelium, dendritic interstitial fibroblastic cells, and endoneurial cells as well as with the neoplastic cells in a variety of mesenchymal neoplasms of unknown etiology, such as Kaposi's ...
S, Suster, C, Fisher
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Expression of hematopoietic progenitor cell associated antigen CD34 in chronic myeloid leukemia
Leukemia Research, 1991The expression of progenitor cell associated antigen CD34 was investigated in cells from 28 patients with chronic myeloid leukemia (CML). The CD34 positivity varied from 0-26% in patients with chronic phases CML (n = 17); from 6-64% in patients with accelerated phase CML (n = 4); and from 27-97% in the patients with blastic crisis of CML (n = 8).
S, Banavali +6 more
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[Polyclonal antibodies against human cell-surface antigen CD34].
TSitologiia i genetika, 2011An efficient and inexpensive laboratory approach for the generation and the purification of polyclonal antibodies to human antigen CD34 was developed. It was shown that cloned refolded and purified from Escherichia coli recombinant extracellular fragment of CD34 antigen retained immunogenic determinants of cell-surface expressed CD34.
Iu S, Nikolaev +7 more
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