Results 41 to 50 of about 1,033,264 (210)

IgA response in serum and gut secretion in sensitized mice fed with the dust mite Dermatophagoides pteronyssinus extract

Brazilian Journal of Medical and Biological Research, 2004
Induced oral tolerance to mucosal-exposed antigens in immunized animals is of particular interest for the development of immunotherapeutic approaches to human allergic diseases.
M. Maciel, A.E. Fusaro, C.R. Oliveira, E.A. Futata, A.J.S. Duarte, M.N. Sato   +5 more
doaj   +1 more source

Predictors of allergen sensitization in Singapore children from birth to 3 years [PDF]

, 2016
10.1186/s13223-016-0161-xAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology121Article number 56GUSTO (Growing up towards Healthy ...
A. Goh, B. W. Lee, H. Van Bever, J. Z. Sim, K. Kwek, K. M. Godfrey, L. P. Shek, Loo, E. X., M. S. Kramer, O. H. Teoh, P. D. Gluckman, S. M. Saw, Y. H. Chan, Y. S. Chong   +13 more
core   +2 more sources

Safety of 300IR house dust mite sublingual tablet from pooled clinical trial and post-marketing data

World Allergy Organization Journal
Background: The 300IR house dust mite (HDM) sublingual immunotherapy (SLIT) tablet is approved for treatment of HDM-induced allergic rhinitis (AR).
Margitta Worm, MD, Pascal Demoly, MD, PhD, Yoshitaka Okamoto, MD, PhD, Carmen Vidal, MD, PhD, Katia Daghildjian, PharmD, PhD, Kwok Yan, MD, Thomas B. Casale, MD, Karl-Christian Bergmann, MD, PhD   +7 more
doaj   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Resposta cutânea a alérgenos ambientais em indivíduos atendidos em serviço de pneumologia, Maringá, Estado do Paraná, Brasil = Cutaneous response to environmental allergens in patients attended in pulmonology service of Maringá, Paraná State, Brazil [PDF]

Acta Scientiarum. Health Sciences, 2012
As alergias respiratórias, comumente as rinites e a asma, vêm se tornando cada vez mais frequentes. Considerando que no Noroeste do Paraná há poucos dados referentes ao assunto, propusemos a verificar os agentes causadores de alergias respiratórias e ...
Gustavo Falavigna Guilherme, Valentim Constante Sella, Reynaldo Rafael Brovini, Ana Amélia Montanha, Edson Valdemar Guilherme, Ana Lucia Falavigna   +5 more
doaj  

The Immunological Correlation With Adenoid Hypertrophy and Allergic Rhinitis in Children

iNew Medicine, EarlyView.
The imbalance of Th1/Th2 and Th17/Treg cells in allergen and inflammatory responses might be associated with the development of adenoid hypertrophy, suggesting that allergic rhinitis maybe the risk factor of AH and providing a potential alternative explanation for adenoid hypertrophy pathogenesis.
Yang Song, Chao Zhang, Jun Song, Jian‐Ming Yang, Wei Wei   +4 more
wiley   +1 more source

Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]

, 2011
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene, Flohrs, Katrin, Heinrich, Joachim, Rzehak, Peter, Thiering, Elisabeth, Wichmann, Heinz-Erich   +5 more
core   +1 more source

Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu, Long‐Lan Shu, Tao Lu, Da‐Yu Guan, Bo‐Wen Zheng, Pan‐Hui Xiong, Yang Shen, Yu‐Cheng Yang   +7 more
wiley   +1 more source

Age at Onset of Asthma and Allergen Sensitization Early in Life

Allergology International, 2014
Background: Epidemiological evidence indicates that the age at onset of asthma and allergen sensitization in early life is decreasing in people from Western countries. To explore latent trends, we conducted a retrospective examination of the age at onset
Masahiko Kato, Yoshiyuki Yamada, Kenichi Maruyama, Yasuhide Hayashi   +3 more
doaj   +1 more source

Direct evidence for a functional role of HLA-DRB1 and -DRB3 gene products in the recognition of Dermatophagoides spp. (house dust mite) by helper T lymphocytes [PDF]

, 2017
The contribution of the HLA-DRB1, -B3, and -BS gene products in the recognition of Dermatophagoides spp. (house dust mite) by helper T cells Isolated from an atopic individual (HLA-DRw12, DR7; DRw52b) with perennial rhinitis was investigated.
Bal, Vineeta, Berte, Christine, Greenlaw, Roseanna, Lamb, Jonathan R., Lechier, Robert I., Mach, Bernard, O'Hehir, Robyn E., Tiercy, Jean-Marie, Trowsdale, John   +8 more
core