Results 181 to 190 of about 20,381 (227)

Therapeutic Potential of Helminths and Helminth-Derived Antigens for Resolution of Inflammation in Inflammatory Bowel Disease

Archives of Medical Research, 2019
Inflammation plays a pivotal role in the pathogenesis of inflammatory bowel disease (IBD), and treatment of IBD mainly targets on inhibition of pro-inflammatory mediators. Helminth-based therapy is a novel strategy for resolution of inflammation in IBD, because helminths have great immunomodulatory properties.
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Helminth Antigens Selectively Differentiate Unsensitized CD45RA+CD4+ Human T Cells in Vitro

The Journal of Immunology, 1998
Abstract Human filarial helminth infections are characterized by type 2 immune responses to parasite Ag that can persist for the life of the individual; one possible cause for this may be prenatal exposure to the blood-borne microfilarial (Mf) stage of the parasite.
C, Steel, T B, Nutman
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Chronic helminth infection and helminth‐derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice

The FASEB Journal, 2015
ABSTRACT Chronic low‐grade inflammation associated with obesity contributes to insulin resistance and type 2 diabetes. Helminth parasites are the strongest natural inducers of type 2 immune responses, and short‐lived infection with rodent nematodes was reported to improve glucose tolerance in obese mice.
Hussaarts, L., Garcia-Tardon, N., Beek, L. van, Heemskerk, M.M., Haeberlein, S., Zon, G.C. van der, Ozir-Fazalalikhan, A., Berbee, J.F.P., Dijk, K.W. van, Harmelen, V. van, Yazdanbakhsh, M., Guigas, B.   +11 more
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Antigenic structure of nematodes and prospects for vaccination against helminth infections

Veterinary Science Communications, 1978
Domestic animals may become resistant to parasites. There have been many studies of the nature and role of the antigens involved in this immunological reaction and the results are presented in this paper.
G. Luffau, P. Pery
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In vitro parasite antigen-induced antibody responses in human helminth infections.

The Journal of Immunology, 1985
Abstract Helminth parasites characteristically induce vigorous antibody responses in human infections, but the immunoregulatory mechanisms determining the level of these responses are not at all understood. To investigate these mechanisms, peripheral blood mononuclear cells were obtained from 10 patients with parasitic helminth ...
T B, Nutman, A S, Withers, E A, Ottesen
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Helminth functional antigens (with special reference to S. mansoni).

Pathologie-biologie, 1982
Study of helminth antigens with a special reference to Schistosoma are reviewed, not exhaustively but rather as an overview of trends. These antigens are considered at four levels. Firstly, characterization and utilization of genus, species or stage-specific antigens should improve the efficiency of immunological diagnosis of helminth diseases.
Bout, D, Carlier, Yves
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Workshop 1M: Helminth antigens and genes

International Journal for Parasitology, 1987
R.M.E. Parkhouse, M.J. Howell
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Antigenic and dynamic properties of helminth surface structures

Molecular and Biochemical Parasitology, 1984
M, Philipp, F D, Rumjaneck
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Antigen specificity of the adaptive immune response against helminths

2023
Gastrointestinal helminths are potent inducers of a type 2 immune response and are known for their ability to modulate their host environment. For example, the major human hookworm species, Necator americanus and Ancylostoma duodenale, take up residence in the gastrointestinal tract while benefiting from nutrient supply by feeding on host blood and ...
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Cooperation of ILC2s and TH2 cells in the expulsion of intestinal helminth parasites

Nature Reviews Immunology, 2023
Dietmar Zaiss, Andrew N J Mckenzie, Christoph S N Klose   +2 more
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