Intracytoplasmic antigen study by flow cytometry in hematolymphoid neoplasm
Flow cytometric detection of intracellular antigens has become a standard method in establishing proper leukemic cell lineage affiliation. It has a non-debatable contribution to the diagnosis of hematolymphoid neoplasm as well as in minimal residual disease.
Prashant Tembhare+5 more
doaj +5 more sources
Tissue expression of CD10 protein in colorectal carcinoma: correlation with the anatomopathological features of the tumor and with lymph node and liver metastases [PDF]
BACKGROUND: The reduced expression of CD10 may be related to unfavorable prognosis of patients with colorectal carcinoma. The authors analyzed the tissue immunostaining of CD10 protein in colorectal carcinoma and its relationship to clinicopathologic ...
Levindo Alves de Oliveira+6 more
doaj +3 more sources
Paraneoplastic Pemphigus: Paraneoplastic Autoimmune Disease of the Skin and Mucosa
Paraneoplastic pemphigus (PNP) is a rare but life-threatening mucocutaneous disease mediated by paraneoplastic autoimmunity. Various neoplasms are associated with PNP.
Jong Hoon Kim, Soo-Chan Kim
doaj +2 more sources
Therapeutic Prospects of Extracellular Vesicles in Cancer Treatment
Extracellular vesicles (EVs) are released by all cells within the tumor microenvironment, such as endothelial cells, tumor-associated fibroblasts, pericytes, and immune system cells.
Daria S. Chulpanova+4 more
doaj +2 more sources
Recent advances of chimeric antigen receptor T-cell therapy for acute myeloid leukemia. [PDF]
Acute myeloid leukemia (AML) is a heterogeneously primary hematopoietic neoplasm characterized by uncontrolled proliferation of immature myeloid cells, which is characterized with poor outcomes.
Liu Y+6 more
europepmc +2 more sources
Diagnosis and Clinical Features in Autoimmune-Mediated Movement Disorders [PDF]
Movement disorders are common manifestations in autoimmune-mediated encephalitis. This group of diseases is suspected to be triggered by infection or neoplasm.
Pei-Chen Hsieh, Yih-Ru Wu
doaj +1 more source
Infiltration of plasma cells in colorectal adenocarcinoma associated with autoimmune encephalitis
Paraneoplastic autoimmune encephalitis (PAE) represents a group of rare neurological syndromes associated with neoplastic diseases. Here, we report a case that multiple anti‐neuronal antibodies were present in a patient with PAE who developed both small ...
Yaqing Shu+9 more
doaj +1 more source
Hairy Projections on Non Hairy Cells- A Case Report [PDF]
Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2,
Rhituparna Das+2 more
doaj +1 more source
Mathematical Modeling Insights into Improving CAR T cell Therapy for Solid Tumors: Antigen Heterogeneity and Bystander Effects [PDF]
As an adoptive cellular therapy, Chimeric Antigen Receptor T-cell (CAR T-cell) therapy has shown remarkable success in hematological malignancies, but only limited efficacy against solid tumors. Compared with blood cancers, solid tumors present a unique set of challenges that ultimately neutralize the function of CAR T-cells.
arxiv +1 more source
PTEN expression in patients with carcinoma of the cervix and its association with p53, Ki-67 and CD31 [PDF]
PURPOSE: To investigate protein expression and mutations in phosphatase and tensin homolog (PTEN) in patients with stage IB cervical squamous cell carcinoma (CSCC) and the association with clinical-pathologic features, tumor p53 expression, cell ...
Luciano Fernandes Loures+5 more
doaj +1 more source