Results 41 to 50 of about 131,754 (303)

Impact of cytotoxic T lymphocytes immunotherapy on prognosis of colorectal cancer patients

Frontiers in Oncology, 2023
BackgroundExpansion and activation of cytotoxic T lymphocytes (CTLs) in vitro represents a promising immunotherapeutic strategy, and CTLs can be primed by dendritic cells (DCs) loaded with tumor-associated antigens (TAAs) transformed by recombinant adeno-
Yankun Zhu, Mingyao Meng, Zongliu Hou, Wenju Wang, Lin Li, Aoran Guan, Ruotian Wang, Weiwei Tang, Fang Yang, Yiyi Zhao, Hui Gao, Hui Xie, Ruhong Li, Jing Tan   +13 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Blastic Plasmacytoid Dendritic Cell Neoplasm Expressing the CD13 Myeloid Antigen

, 2011
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), currently considered to originate from immature plasmacytoid dendritic cells (DC), is a rare and aggressive CD4+CD56+ neoplasm that frequently involves the skin and bone marrow.
Takayuki Takahashi, Seiji Nagano, Kiminari Ito, Yukihiro Imai, Takayuki Ishikawa, Kyoko Maruyama, Daichi Inoue, Hayato Maruoka, Kazunari Aoki   +8 more
core   +1 more source

Blastic plasmacytoid dendritic cell neoplasm: diagnostic criteria and therapeutical approaches [PDF]

, 2016
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematological malignancy derived from the precursors of plamacytoid dendritic cells, with an aggressive clinical course and high frequency of cutaneous and bone marrow involvement ...
GRAMMATICO, SARA, Alessandro Pulsoni, Valentini, Caterina Giovanna, Sara Grammatico, Valentini, Caterina G, PULSONI, Alessandro, Livio Pagano, Caterina G. Valentini, Pagano, Livio   +8 more
core   +1 more source

High-Grade Epstein-Barr Virus-Negative Biphenotypic Lymphoma with Expression of B- and T-Cell Markers and Leukemia Presentation: Case Report and Literature Review

Case Reports in Oncology, 2020
Lymphomas are presently categorized according to their origin from B or T lymphocytes. The co-expression of CD3 in B-cell lymphomas or CD20 in T-cell lymphomas has been rarely reported.
Samah Kohla, Feryal A. Ibrahim, Deena Mudawi, Susanna Akiki, Dina Soliman, Ahmad Al-Sabbagh, Reda R.H. Youssef, Mohamed A. Yassin   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Macrophage Electrophoretic Migration Test for Lymphocyte Sensitization to Tumor Antigens.

, 1974
The macrophage electrophoretic migration test (MEM test) of Field and Caspary was used to study the sensitization to tumor antigens of blood lymphocytes of patients with solid tumor (7), chronic lymphatic leukemia (3), and Hodgkin's disease (8).
Carlo Floris, Sergio Tognella, Gennaro S. Del Giacco, Vincenzo Grifoni, Giovanni Mantovani, Letizia Cengiarotti   +5 more
core   +1 more source

Advancements in Chimeric Antigen Receptor T Cell Therapy for Hepatocellular Carcinoma [PDF]

E3S Web of Conferences
Chimeric antigen receptor T cell (CAR-T) therapy nowadays symbolizes an innovative paradigm of neoplasm immunotherapy that employs genetic engineering techniques to empower T cells and make it have a capability to precisely identify tumor-associated ...
Zhao Xinyu
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Clinical value of carcinoembryonic antigen in mammary neoplasms of bitches

Veterinary and Comparative Oncology, 2019
AbstractThis study aimed at evaluating the behaviour and understanding the diagnostic value of the carcinoembryonic antigen (CEA) in bitches with mammary carcinoma as a tool for monitoring and prognosis of canine cancer patients. Serum samples from 77 bitches were divided into four groups, G1 (n = 21), control group (healthy/neoplasia free bitches); G2
Igor L. S. Senhorello, Erika M. Terra, Felipe A. R. Sueiro, Bruna F. Firmo, Leticia A. Anai, Camila Goloni, Isabela C. Canavari, Roberto A. N. Ampuero, Rodrigo S. Pereira, Mirela Tinucci‐Costa   +9 more
openaire   +3 more sources