Results 41 to 50 of about 132,020 (265)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Osteochondroma in a young cat infected by feline leukemia virus

Ciência Rural
: Osteochondromas are primary bone tumors characterized by cartilage-covered bone projections involving single or multiple masses (osteochondromatosis).
Matheus de Oliveira Reis, Lauren Santos de Mello, Kivia Lunardelli Hesse, Marina Paula Lorenzett, Kauê Danilo Helene Lemos dos Reis, Fabrício Souza Campos, Paulo Michel Roehe, Saulo Petinatti Pavarini   +7 more
doaj   +1 more source

Impact of cytotoxic T lymphocytes immunotherapy on prognosis of colorectal cancer patients

Frontiers in Oncology, 2023
BackgroundExpansion and activation of cytotoxic T lymphocytes (CTLs) in vitro represents a promising immunotherapeutic strategy, and CTLs can be primed by dendritic cells (DCs) loaded with tumor-associated antigens (TAAs) transformed by recombinant adeno-
Yankun Zhu, Mingyao Meng, Zongliu Hou, Wenju Wang, Lin Li, Aoran Guan, Ruotian Wang, Weiwei Tang, Fang Yang, Yiyi Zhao, Hui Gao, Hui Xie, Ruhong Li, Jing Tan   +13 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

High-Grade Epstein-Barr Virus-Negative Biphenotypic Lymphoma with Expression of B- and T-Cell Markers and Leukemia Presentation: Case Report and Literature Review

Case Reports in Oncology, 2020
Lymphomas are presently categorized according to their origin from B or T lymphocytes. The co-expression of CD3 in B-cell lymphomas or CD20 in T-cell lymphomas has been rarely reported.
Samah Kohla, Feryal A. Ibrahim, Deena Mudawi, Susanna Akiki, Dina Soliman, Ahmad Al-Sabbagh, Reda R.H. Youssef, Mohamed A. Yassin   +7 more
doaj   +1 more source

Advancements in Chimeric Antigen Receptor T Cell Therapy for Hepatocellular Carcinoma [PDF]

E3S Web of Conferences
Chimeric antigen receptor T cell (CAR-T) therapy nowadays symbolizes an innovative paradigm of neoplasm immunotherapy that employs genetic engineering techniques to empower T cells and make it have a capability to precisely identify tumor-associated ...
Zhao Xinyu
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Clinical value of carcinoembryonic antigen in mammary neoplasms of bitches

Veterinary and Comparative Oncology, 2019
AbstractThis study aimed at evaluating the behaviour and understanding the diagnostic value of the carcinoembryonic antigen (CEA) in bitches with mammary carcinoma as a tool for monitoring and prognosis of canine cancer patients. Serum samples from 77 bitches were divided into four groups, G1 (n = 21), control group (healthy/neoplasia free bitches); G2
Igor L. S. Senhorello, Erika M. Terra, Felipe A. R. Sueiro, Bruna F. Firmo, Leticia A. Anai, Camila Goloni, Isabela C. Canavari, Roberto A. N. Ampuero, Rodrigo S. Pereira, Mirela Tinucci‐Costa   +9 more
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source