Results 41 to 50 of about 1,322,361 (357)

Dedifferentiation of B-lymphoblastic leukemia/lymphoma with t(9;22) BCR::ABL1 to an undifferentiated neoplasm with strong keratin expression in a patient receiving blinatumomab

open access: yesHuman Pathology Reports, 2023
Objectives: Lineage switch in patients with B-ALL treated with blinatumomab has been previously reported. We present a case of blinatumomab-treated B-ALL with t(9;22)(q34.1;q11.2) (Ph + B-ALL) relapsing as a keratin-positive undifferentiated neoplasm ...
Krasimira A. Rozenova   +10 more
doaj  

Locally Advanced Spiroadenocarcinoma in the Regional Axilla of a Breast Cancer Patient: Hallmarks of Definitive Diagnosis and Management. [PDF]

open access: yes, 2015
Eccrine spiroadenocarcinoma is an extremely rare malignant eccrine gland tumor which may masquerade as other more common malignancies such as poorly differentiated squamous carcinoma or metastatic breast cancer.
Canter, Robert J   +3 more
core   +2 more sources

The immune response to class I-associated tumor-specific cutaneous T-cell lymphoma antigens.

open access: yesJournal of Investigative Dermatology, 1996
In order to determine whether the neoplastic T cells from patients with cutaneous T-cell lymphoma express tumor-specific antigens that can serve as the targets of an immune response, we took advantage of family-specific monoclonal antibodies, magnetic ...
C. Berger   +5 more
semanticscholar   +1 more source

Evaluation of Angiogenesis in Colorectal Carcinoma by CD34 Immunohistochemistry Method and its Correlation with Clinicopathologic Parameters [PDF]

open access: yesActa Medica Iranica, 2009
The basic pathogenic step in the process of tumor growth, invasion and metastasis is tumor-induced angiogenesis. The aim of this study was to evaluate the angiogenesis in colorectal carcinoma by microvascular density (MVD) determination with IHC ...
Sharifi Nourieh   +5 more
doaj   +2 more sources

Fibrosarcoma: Origin, differential diagnosis, and report of a case in the mandible

open access: yesJournal of Indian Society of Periodontology, 2022
Fibrosarcoma (FS) is a malignant neoplasm of mesenchymal cells with no specific line of differentiation. Histologically, it mimics the wide spectrum of benign and malignant spindle cell neoplasms creating diagnostic conundrum.
Harpreet Kaur   +3 more
doaj   +1 more source

Analysis of cancer/testis antigens in sporadic medullary thyroid carcinoma: expression and humoral response to NY-ESO-1.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2003
Cancer/testis antigens (CTA) are tumor-associated antigens expressed during ontogenesis, in a number of solid tumors but not in normal tissues except testis.
M. Maio   +11 more
semanticscholar   +1 more source

Autoantibody profiling of benign and malignant thyroid tumors and design of a prototype diagnostic array

open access: yesЭндокринная хирургия, 2012
Currently the “gold standard” in diagnostics of thyroid tumors is a fine-needle aspiration cytology (FNAC). However, FNAC cannot discriminate between benign and malignant thyroid tumors in 15 to 30% of observations. In order to develop an additional tool
K V Lanshchakov   +5 more
doaj   +1 more source

Impact of cytotoxic T lymphocytes immunotherapy on prognosis of colorectal cancer patients

open access: yesFrontiers in Oncology, 2023
BackgroundExpansion and activation of cytotoxic T lymphocytes (CTLs) in vitro represents a promising immunotherapeutic strategy, and CTLs can be primed by dendritic cells (DCs) loaded with tumor-associated antigens (TAAs) transformed by recombinant adeno-
Yankun Zhu   +13 more
doaj   +1 more source

Computational Intelligence Approach to Improve the Classification Accuracy of Brain Neoplasm in MRI Data [PDF]

open access: yesarXiv, 2021
Automatic detection of brain neoplasm in Magnetic Resonance Imaging (MRI) is gaining importance in many medical diagnostic applications. This report presents two improvements for brain neoplasm detection in MRI data: an advanced preprocessing technique is proposed to improve the area of interest in MRI data and a hybrid technique using Convolutional ...
arxiv  

Regulation of T cell expansion by antigen presentation dynamics [PDF]

open access: yesPNAS 2019, 116 (13) 5914-5919, 2018
An essential feature of the adaptive immune system is the proliferation of antigen-specific lymphocytes during an immune reaction to form a large pool of effector cells. This proliferation must be regulated to ensure an effective response to infection while avoiding immunopathology.
arxiv   +1 more source

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