Results 61 to 70 of about 137,149 (293)

Serum and Salivary Cea and Gica Levels in Oral Cavity Tumours

The International Journal of Biological Markers, 1988
The gastrointestinal cancer-associated antigen (GICA) is recognised by a monoclonal antibody in both serum and tissues ofpatients with neoplasm of the GI tract. This study compared the serum and saliva values of carcinoembryonic antigen (CEA) and GICA in
L. Negri, D. Pacchioni, F. Calabrese, S. Giacomasso, V. Mastromatteo, M. Fazio   +5 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Unraveling the potential: mRNA therapeutics in oncology

Frontiers in Oncology
Messenger ribonucleic acid (mRNA) technology is a promising platform for cancer immunotherapy. Unlike traditional vaccines that prevent infectious diseases, mRNA’s role in oncology is to stimulate or enhance the immune response against tumor antigens ...
Karol Gawalski, Karol Gawalski, Weronika Przybyszewska, Weronika Przybyszewska, Jaromir Hunia, Jaromir Hunia, Alicja Gawalska, Aleksandra Rymarz   +7 more
doaj   +1 more source

Tumor Markers in the Diagnosis, Monitoring and Therapy of Pancreatic Cancer: State of the Art

The International Journal of Biological Markers, 1995
The present review focuses on the utility of serum tumor markers in screening, diagnosis, prognosis and monitoring of pancreatic cancer. Serum determination of all tumor markers studied offers no help in screening or early diagnosis of pancreatic cancer.
M. Plebani, D. Basso, M.P. Panozzo, P. Fogar, G. Del Favero, R. Naccarato   +5 more
doaj   +1 more source

Paraneoplastic pemphigus: insight into the autoimmune pathogenesis, clinical features and therapy [PDF]

, 2017
Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients.
Andrea Ciofalo, Biagio Didona, Bialy-Golan, Dario Didona, Elisa Moliterni, Giannicola Iannella, Giovanni Paolino, Giuseppe Magliulo, Guido Granata, Hainsworth, Martínez De Pablo, Matz, Michele Donati, Mutasim, Nguyen, Patricia Ranuzzi, Santo Mercuri, Schepens, Stefano Calvieri, Su, Vincenzo Falasca, Zimmermann   +21 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Radio Immuno Imaging and Therapy

Journal of Indian Academy of Oral Medicine and Radiology, 2006
Inherent in the application of advances in biomedical science to nuclear medicine is the concept of molecular targeting. Radioimmunoimaging and therapy can add a new dimension to diagnostic imaging and staging of head and neck cancer including metastasis,
P Raghu Obul Reddy, M C Shashikanth, I M Ali   +2 more
doaj  

Follicular dendritic cell sarcoma with paraneoplatic pemphigus: Rare case and a brief review of literature

Indian Journal of Medical and Paediatric Oncology, 2013
Paraneoplastic pemphigus (PNP) is often a fatal autoimmune bullous disease characterized by severe stomatitis, polymorphous skin eruptions, and underlying neoplasms. We describe a patient with PNP associated with follicular dendritic cell sarcoma (FDCS),
Saphalta Baghmar, Sanjeev Kumar, S Dutta Gupta, Vinod Raina   +3 more
doaj   +1 more source

Endoscopic ultrasound guided radiofrequency ablation, for pancreatic cystic neoplasms and neuroendocrine tumors

, 2015
AIM: To outline the feasibility, safety, adverse events and early results of endoscopic ultrasound (EUS)-radiofrequency ablation (RFA) in pancreatic neoplasms using a novel probe. METHODS: This is a multi-center, pilot safety feasibility study.
Beckebaum, S, Brugge, W, Cicinnati, VR, Drymousis, P, Habib, N, Kaba, I, Kahaleh, M, Lakhtakia, S, Pai, M, Reddy, N, Senturk, H   +10 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source