Developing the next-generation of adenoviral vector vaccines. [PDF]
Sampson AT+4 more
europepmc +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu+13 more
wiley +1 more source
<i>In silico</i> design of immunogenic antigen cocktail via affinity maturation-guided optimization. [PDF]
Abeer ANMN, Koo BS, Yoon BJ.
europepmc +1 more source
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao+10 more
wiley +1 more source
Construction and Evaluation of Quadruple-Gene-Deleted Pseudorabies Virus Platforms for ASFV Antigen Delivery. [PDF]
Li H+11 more
europepmc +1 more source
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao+17 more
wiley +1 more source
HLA class-I-transgenic mice as model system to study MHC-restricted antigen recognition in man [PDF]
A. McMichael+19 more
core +1 more source
Factors determining the outcomes of immune imprinting after repeated orthoflavivirus infections. [PDF]
Salem GM, Chen FC, Cai JJ, Chao DY.
europepmc +1 more source
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang+10 more
wiley +1 more source
Evaluation of Recombinant Foot-and-Mouth Disease SAT2 Vaccine Strain in Terms of Antigen Productivity, Virus Inactivation Kinetics, and Immunogenicity in Pigs for Domestic Antigen Bank. [PDF]
Kim JY+6 more
europepmc +1 more source