Results 1 to 10 of about 2,837,216 (296)

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

Advanced Science
Tumor mutational burden (TMB), usually representing high immunogenicity, cannot always predict treatment response of immune checkpoint blockade (ICB).
Ruxin Wang, Yunyi Zhang, Xiangyu Meng, Jianli Zhao, Yue Xing, Qian Ouyang, Ning Zhang, Huiping Chen, Nanyan Miao, Erwei Song, Di Huang   +10 more
doaj   +1 more source

Improved antigen cross-presentation by polyethyleneimine-based nanoparticles

International Journal of Nanomedicine, 2011
Jian Chen1, Zhengrong Li1, Hong Huang2, Yanzhu Yang2, Qian Ding2, Junhua Mai1, Wei Guo2, Yuhong Xu21School of Life Sciences and Biotechnology, 2School of Pharmacy, Shanghai Jiao Tong University, Shanghai, People's Republic of ChinaPurpose: In the
Jian Chen, Zhengrong Li, Hong Huang, et al   +3 more
doaj  

The ubiquitin-like modifier FAT10 is not essential for MHC-I antigen presentation

Frontiers in Immunology
IntroductionThe presentation of pathogen-derived antigens on major histocompatibility complex (MHC) class I is crucial for the antiviral immune response. Degradation of intracellular pathogen-derived proteins by the 26S proteasome generates peptides that
Natalie Pach, Natalie Pach, Sarah Ochs, Jinjing Cao, Julia Ottlinger, Annette Aichem, Michael Basler, Michael Basler   +7 more
doaj   +1 more source

Mediators of Inflammation and Immune Responses in the Human Gastrointestinal Tract

Mediators of Inflammation, 2013
E. Arranz, A. S. Peña, D. Bernardo
doaj   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science
Cancer vaccines have demonstrated initial effectiveness in the treatment of human cancers, still the low mutational burden, which leads to a deficiency of well‐characterized antigens expressed within tumors capable of mediating tumor rejection, poses a ...
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
doaj   +1 more source

CXCL16 knockout inhibit asthma airway inflammation by suppressing H2-DM molecular mediated antigen presentation

Cell Death Discovery
The inflammatory microenvironment influences dendritic cell-mediated antigen presentation to regulate asthma Th2 inflammation. The scavenger receptor is expressed on DCs and regulates antigen presentation and T priming. However, whether the transmembrane
Ting-ting Liu, Zhi Zhang, Jing Deng, Chang-yu Shi, Shuai Zheng, Li-xin Jia, Jie Du, Chunmei Piao   +7 more
doaj   +1 more source

Commentary Frontiers in ImmunologyThe tricky balancing act of using heat shock proteins for cross-presentation

Frontiers in Immunology, 2012
Willem eVan Eden, Alice eSijts
doaj   +1 more source

Intestinal Microbiota as Modulators of the Immune System

Journal of Immunology Research, 2015
Borja Sánchez, Miguel Gueimonde, Amado Salvador Peña, David Bernardo   +3 more
doaj   +1 more source

The Impact of Antigen Presentation on BBB Disruption and Neuroinflammation. [PDF]

Physiology (Bethesda)
Maynes MA, Johnson AJ.
europepmc   +1 more source

Antigen presentation requirements for effective cDC1-based cancer immunotherapy. [PDF]

J Immunol
Pineda JE, Minowa T, Shen L, Zhou Y, Dyevoich A, Patel B, Schneider SM, Keshari S, Saha A, Riba MN, Wang J, Watowich SS, Gubin MM.   +12 more
europepmc   +1 more source