Results 21 to 30 of about 532,042 (312)
Mediators of Inflammation, 2013 Background. Dendritic cells regulate immune responses to microbial products and play a key role in ulcerative colitis (UC) pathology. We determined the immunomodulatory effects of probiotic strain Lactobacillus casei Shirota (LcS) on human DC
Elizabeth R. Mann +12 more
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Identification and molecular characterization of oat peptides implicated on coeliac immune response
Food & Nutrition Research, 2016 Background: Oats provide important nutritional and pharmacological properties, although their safety in coeliac patients remains controversial. Previous studies have confirmed that the reactivity of the anti-33-mer monoclonal antibody with different oat ...
Isabel Comino +11 more
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Antigen presentation and T cell regulation by intestinal epithelial cells
, 2022 Major histocompatibility complex (MHC) class II expression by intestinal epithelial cells (IECs) has been described in inflammatory bowel disease patients.
Heuberger, Cornelia
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HLA-E Peptide Repertoire and Dimorphism—Centerpieces in the Adaptive NK Cell Puzzle?
Frontiers in Immunology, 2018 Adaptive Natural Killer (NK) cells, a heterogenous subpopulation of human NK cells with a unique phenotypic and functional signature, became arguably one of the central areas of interest in the field.
Alexander Rölle +4 more
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Antigen - presentation by vascular endothelium : its role for CTL - mediated vascular injury [PDF]
, 2008 Background: EC express and present MHC class I restricted peptide antigens and due to the exposed position may be targeted by antigen-specific CTL. We wished to explore the type of vascular injury that is mediated by peptidespecific CTL in vivo when EC ...
Wang, Xueya
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Immunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADF. [PDF]
PLoS ONE, 2012 Dynamic changes in the actin cytoskeleton are essential for immune cell function and a number of immune deficiencies have been linked to mutations, which disturb the actin cytoskeleton.
Friederike Jönsson +4 more
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Endothelial cells as targets for antigen-specific cytotoxic T lymphocytes [PDF]
, 2010 BACKGROUND: In this study we have examined human vascular endothelial cells as targets for antigen-specific cytotoxic T lymphocytes (CTL). Vascular endothelial cells (EC) act as the major interface between blood and tissues and are crucial for the ...
Thommen, Daniela Stefanie
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, 2022 Despite its crucial role in initiation of cytotoxic immune responses, the molecular pathways underlying antigen cross-presentation remain incompletely understood.
Richard Simpson (9487685) +13 more
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The role of insulin-regulated aminopeptidase in MHC class I antigen presentation
Frontiers in Immunology, 2012 Production of MHC I ligands from antigenic proteins generally requires multiple proteolytic events. While the proteolytic steps required for antigen processing in the endogenous pathway are clearly established, persisting gaps of knowledge regarding ...
Peter M Van Endert, Loredana eSaveanu
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Antigen Cross-Presentation by Macrophages
Frontiers in Immunology, 2020 The contribution of dendritic cell (DC) antigen cross-presentation to the activation of CD8+ T lymphocytes for immune defense against tumors, viruses, and intracellular pathogens has been recognized widely.
Elke M. Muntjewerff +3 more
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