Results 41 to 50 of about 534,463 (213)

Antigen presentation by MHC-dressed cells

open access: yesFrontiers in Immunology, 2015
Professional antigen presenting cells (APCs) such as conventional dendritic cells (DCs) process protein antigens to MHC-bound peptides and then present the peptide-MHC complexes to T cells.
Masafumi eNakayama
doaj   +1 more source

Antigen-presentation efficacy of PLGA NPs-pulsed DCs. [PDF]

open access: yes, 2017
(A) Antigen-presentation efficacy of PLGA NPs-pulsed DCs to naive splenocytes. Splenocytes treated with medium alone served as negative control. The results are the mean stimulation index (S.I.)±SD from three independent experiments.
Evita Athanasiou (2265688)   +8 more
core   +1 more source

Presentation of hepatocellular antigens [PDF]

open access: yesCellular & Molecular Immunology, 2016
The liver is an organ in which antigen-specific T-cell responses manifest a bias toward immune tolerance. This is clearly seen in the rejection of allogeneic liver transplants, and multiple other phenomena suggest that this effect is more general.
Grakoui, Arash, Crispe, Ian Nicholas
openaire   +2 more sources

Antigen Processing and Presentation in Multiple Sclerosis [PDF]

open access: yes, 2009
CD4(+) T cells play a central role in the pathogenesis of multiple sclerosis (MS). Generation, activation and effector function of these cells crucially depends on their interaction with MHC II-peptide complexes displayed by antigen presenting cells (APC)
Tolosa, Eva   +3 more
core   +1 more source

Efficient Capsid Antigen Presentation From Adeno-Associated Virus Empty Virions In Vivo

open access: yesFrontiers in Immunology, 2018
Adeno-associated virus (AAV) vectors have been successfully applied in clinical trials for hemophilic patients. Although promising, the clinical results suggest that the capsid-specific CD8+T cell response has a negative effect on therapeutic success. In
Xiaolei Pei   +10 more
doaj   +1 more source

Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD) [PDF]

open access: yes, 2004
Dendritic cells (DC) are known to present exogenous protein Ag effectively to T cells. In this study we sought to identify the proteases that DC employ during antigen processing.
Mansour Mohamadzadeh   +9 more
core   +1 more source

Human Antigen Presentation Score.rar [PDF]

open access: yes, 2023
Human Antigen Presentation Score ...
Xiuli Zhu (17597247)
core   +1 more source

Assessment of In Vitro Immunostimulatory Activity of an Adjuvanted Whole-Cell Inactivated Neisseria gonorrhoeae Microparticle Vaccine Formulation

open access: yesVaccines, 2022
The emergence of drug-resistant gonorrhea infections worldwide combined with the lack of a vaccine is alarming. We prepared a novel microparticulate (MP) vaccine formulation using whole-cell inactivated Neisseria gonorrhoeae as the vaccine antigen, with ...
Priyal Bagwe   +4 more
doaj   +1 more source

Effect of hypochlorous acid on antigen processing and presentation [PDF]

open access: yes, 2010
Dendritic cells play a key role in both innate and adaptive immunity. Recognition and presentation of antigens on the major histocompatibility complex (MHC) provide an efficient response against infections.
Prokopowicz, Z.M.
core  

MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection

open access: yesFrontiers in Immunology
Peptide-loaded MHC class I (pMHC-I) multimers have revolutionized our capabilities to monitor disease-associated T cell responses with high sensitivity and specificity.
Marten Meyer   +46 more
doaj   +1 more source

Home - About - Disclaimer - Privacy