Immunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADF. [PDF]
PLoS ONE, 2012 Dynamic changes in the actin cytoskeleton are essential for immune cell function and a number of immune deficiencies have been linked to mutations, which disturb the actin cytoskeleton.
Friederike Jönsson +4 more
doaj +1 more source
Presentation slides for the BPPB article entitled Antigen Tests for COVID-19
, 2021 This is a file for the presentation slides for the article entitled "Antigen Tests for COVID-19" published in Biophysics and Physicobiology in ...
Etsuro Ito (11428447)
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The role of insulin-regulated aminopeptidase in MHC class I antigen presentation
Frontiers in Immunology, 2012 Production of MHC I ligands from antigenic proteins generally requires multiple proteolytic events. While the proteolytic steps required for antigen processing in the endogenous pathway are clearly established, persisting gaps of knowledge regarding ...
Peter M Van Endert, Loredana eSaveanu
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Studies on the role of cholesterol and coronin 1 in antigen-presenting cells [PDF]
, 2005 Antigen recognition and presentation to subsequently induce an appropriate host response is dependent on the action of antigen-presenting cells such as dendritic cells and macrophages.
Albrecht, Imke
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COVID-19: Attacks Immune Cells and Interferences with Antigen Presentation through MHC-Like Decoy System [PDF]
, 2021 The high mortality of COVID-19 is related to poor antigen presentation and lymphopenia. In this present study, domain search results showed that many proteins of the SARS-COV-2 virus had MHC-like domains, which were similar to decoys for the human immune
liu, wenzhong, li, hualan
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Transmembrane Helices Are an Overlooked Source of Major Histocompatibility Complex Class I Epitopes
Frontiers in Immunology, 2017 About a fourth of the human proteome is anchored by transmembrane helices (TMHs) to lipid membranes. TMHs require multiple hydrophobic residues for spanning membranes, and this shows a striking resemblance with the requirements for peptide binding to ...
Frans Bianchi +2 more
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Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA class I) allotypes
eLife, 2023 The extreme polymorphisms of human leukocyte antigen class I (HLA class I) proteins enable the presentation of diverse peptides to cytotoxic T lymphocytes.
Eli Olson +2 more
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Antigen - presentation by vascular endothelium : its role for CTL - mediated vascular injury [PDF]
, 2008 Background: EC express and present MHC class I restricted peptide antigens and due to the exposed position may be targeted by antigen-specific CTL. We wished to explore the type of vascular injury that is mediated by peptidespecific CTL in vivo when EC ...
Wang, Xueya
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Restoration of cytomegalovirus antigen presentation by gamma interferon combats viral escape. [PDF]
, 1994 An immediate-early protein of murine cytomegalovirus (MCMV), pp89, elicits an immunodominant and protective major histocompatibility complex (MHC) class I Ld-restricted CD8+ T-lymphocyte response.
Stipan Jonjic +11 more
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Antigen presentation by MHC-dressed cells
Frontiers in Immunology, 2015 Professional antigen presenting cells (APCs) such as conventional dendritic cells (DCs) process protein antigens to MHC-bound peptides and then present the peptide-MHC complexes to T cells.
Masafumi eNakayama
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