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Metabolomic insights into variable antihistamine responses in allergic rhinitis: unveiling biomarkers for precision treatment [PDF]

open access: yesFrontiers in Immunology
BackgroundThe clinical response to antihistamine therapy exhibits substantial heterogeneity among individuals with allergic rhinitis (AR). While these medications represent a cornerstone in AR management, the molecular basis underlying differential ...
Xiaohong Lyu   +11 more
doaj   +2 more sources

The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria [PDF]

open access: yesActa Dermato-Venereologica
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predictors
Yingyi Li   +3 more
doaj   +2 more sources

Administration of Desloratadine for Postorgasmic Illness Syndrome in a Japanese Teenager [PDF]

open access: yesIJU Case Reports
Introduction Postorgasmic illness syndrome is a rare condition occurring after ejaculation. This syndrome can significantly affect the quality of life of patients.
Kaoru Ito   +9 more
doaj   +2 more sources

Influence of the H1 Antihistamine Mepyramine on the Antibacterial Effect of Florfenicol in Pigs

open access: yesVeterinary Sciences, 2021
The effect of florfenicol against Escherichia coli (E. coli) was investigated in vivo to confirm results of an in vitro study of Bruer et al. (2019), which has shown positive effects of various antibacterial agents in combination with the antihistamine ...
Gustav G. Bruer   +3 more
doaj   +1 more source

Ameliorative Effect of a Neoteric Regimen of Catechin plus Cetirizine on Ovalbumin-Induced Allergic Rhinitis in Rats

open access: yesLife, 2022
Allergic rhinitis (AR) affects 20–50% of the global population. Available treatments are limited by their adverse effects. We investigated the anti-allergic effects of catechin alone and combined with cetirizine against ovalbumin-induced AR.
Mohamed A. Morsy   +7 more
doaj   +1 more source

Real-life experience of efficacy and safety of bilastine in the refractory cases of chronic spontaneous urticaria and its effect on the quality of life of patients

open access: yesIndian Journal of Dermatology, 2021
Introduction: Second-generation H1-antihistamines (SGAHs) are the mainstay of treatment of chronic spontaneous urticaria (CSU). Bilastine, newer non-sedating SGAHs, was recently introduced in India after the approval of the Drugs Controller General of ...
Abhishek De   +3 more
doaj   +1 more source

Expert opinion on the role of bilastine and bilastine-montelukast combination in the management of allergic rhinitis: An Indian perspective

open access: yesThe Journal of Association of Chest Physicians, 2023
In India, the burden of allergic rhinitis (AR) is enormous, comprising 55% of all patients with allergies. Intranasal corticosteroids are the recommended first-line therapy for patients with moderate-to-severe AR, particularly when nasal congestion is ...
Subir Jain   +4 more
doaj   +1 more source

Japanese Guidelines for Diagnosis and Treatment of Urticaria in Comparison with Other Countries

open access: yesAllergology International, 2012
Several guidelines for urticaria and angioedema have been published in Europe and United States since 1997. General principles for diagnosis and treatments of them are similar.
Michihiro Hide, Takaaki Hiragun
doaj   +1 more source

Association between First-Generation Antihistamine Use in Children and Cardiac Arrhythmia and Ischemic Heart Disease: A Case-Crossover Study

open access: yesPharmaceuticals, 2023
Cardiotoxicity from first-generation H1-antihistamines has been debated since the 1990s. However, large-scale studies on this topic in a general pediatric population are lacking.
Ju Hee Kim   +7 more
doaj   +1 more source

Preserved Ophthalmic Anti-Allergy Medication in Cumulatively Increasing Risk Factors of Corneal Ectasia

open access: yesBiology, 2023
The prevalence of allergies is rising every year. For those who suffer from it, ocular inflammation and irritation can be inconvenient and unpleasant.
Tom Paterson   +4 more
doaj   +1 more source

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