Results 21 to 30 of about 60,702 (193)

Evidence Gaps in Clinical Trials of Pharmacologic Treatments for H1-Antihistamine-Refractory CSU

open access: yes, 2022
 Details of the dataset of  participant and trial characteristics and reporting of outcome in clinical trials of pharmacologic treatments for H1-antihistamine-refractory chronic spontaneous ...
Surapon Nochaiwong (9736187)
core   +1 more source

Supplementary Material for: Skin Treatment with Detergent Induces Dermatitis with H1-Antihistamine-Refractory Itch and Upregulates IL-4 and Th17/Th22 Cytokine Gene Expression in C57BL/6 Mice

open access: yes, 2022
Introduction: Repeated skin contact to detergents causes chronic irritant contact dermatitis (ICD) associated with itch sensation and eczema. However, the mechanisms of detergent-induced ICD are poorly understood.
Takai T. (13203828)   +14 more
core   +1 more source

OXIME-CONTAINING CONGENERS OF THE ANTIHISTAMINE DIPHENHYDRAMINE.

open access: yes, 1974
OXIME-CONTAINING CONGENERS OF THE ANTIHISTAMINE ...
LEILANI LEE. NIXON (7982273)
core   +4 more sources

Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance New drugs targeting multiple Plasmodium parasite life stages are desperately needed to combat malaria drug resistance. The antihistamine clemastine inhibits multiple parasite forms with previously unknown molecular targets.
Kuan‐Yi Lu   +5 more
semanticscholar   +1 more source

Antihistamine-Induced Hepatitis: 2 Cases Involving Loratidine [PDF]

open access: yes, 2016
Antihistamine-induced hepatitis is rare. We present 2 cases of antihistamine-induced hepatitis with autoimmune features, caused by loratidine. One case was confirmed by rechallenge.
Arsalan Khan   +4 more
core   +1 more source

The KAAACI/KDA Evidence-Based Practice Guidelines for Chronic Spontaneous Urticaria in Korean Adults and Children: Part 2. Management of H1-Antihistamine-Refractory Chronic Urticaria

open access: yesAllergy Asthma and Immunology Research, 2020
Quite a few patients with chronic spontaneous urticaria (CSU) are refractory to H1-antihistamines, even though the dose of H1-antihistamines is increased up to 4-fold. CSU that is not controlled with H1-antihistamines results in increased disease burden.
Jeong-Hee Choi   +41 more
semanticscholar   +1 more source

Use of antihistamine medications during early pregnancy and selected birth defects: The National Birth Defects Prevention Study, 1997–2011

open access: yesBirth Defects Research, 2020
It is estimated that approximately 10–15% of pregnant women report antihistamine use during pregnancy. Although antihistamines are generally considered safe during pregnancy, results from published studies are inconsistent.
C. Hansen   +5 more
semanticscholar   +1 more source

Japanese Guidelines for Diagnosis and Treatment of Urticaria in Comparison with Other Countries

open access: yesAllergology International, 2012
Several guidelines for urticaria and angioedema have been published in Europe and United States since 1997. General principles for diagnosis and treatments of them are similar.
Michihiro Hide, Takaaki Hiragun
doaj   +1 more source

Therapeutic targeting of eosinophil adhesion and accumulation in allergic conjunctivitis

open access: yesFrontiers in Pharmacology, 2012
Considerable evidence indicates that eosinophils are important effectors of ocular allergy. Increased worldwide prevalence of allergic eye pathologies has stimulated the identification of novel drug targets, including eosinophils and adhesion molecules ...
Monica eBaiula   +4 more
doaj   +1 more source

The Antihistamine Drugs Carbinoxamine Maleate and Chlorpheniramine Maleate Exhibit Potent Antiviral Activity Against a Broad Spectrum of Influenza Viruses

open access: yesFrontiers in Microbiology, 2018
Influenza A viruses (IAV) comprise some of the most common infectious pathogens in humans, and they cause significant mortality and morbidity in immunocompromised people as well as children and the elderly.
Wei Xu   +7 more
doaj   +1 more source

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