Results 1 to 10 of about 56,329 (165)
British Journal of Clinical Pharmacology, 2021 Antihistamines are routinely taken to control allergic reactions or sedation to induce sleep. There are, however, growing concerns regarding sedating antihistamine misuse.
Hayley C Gorton, Caroline Copeland
exaly +2 more sources
A retrospective study on the effectiveness and safety of the combination of intranasal corticosteroid and intranasal antihistamine in the management of patients with allergic rhinitis [PDF]
Frontiers in AllergyBackgroundThe Allergic Rhinitis and Its Impact on Asthma 2025 guideline recommends the combination of intranasal corticosteroid and intranasal antihistamine to be used as first-line treatment for moderate-to-severe allergic rhinitis because of its ...
Anil Kumar Monga +5 more
doaj +2 more sources
Nature Medicine, 2021 Bruton’s tyrosine kinase (BTK) is crucial for FcεRI-mediated mast cell activation and essential for autoantibody production by B cells in chronic spontaneous urticaria (CSU).
M. Metz +15 more
semanticscholar +1 more source
Brazilian Journal of Otorhinolaryngology, 2023 Highlights • Rupatadine is the most effective for allergic rhinitis among various oral H1 antihistamines.• Rupatadine 20 mg is more effective for allergic rhinitis than rupatadine 10 mg.• Loratadine 10 mg has inferior efficacy for allergic rhinitis to ...
Dong-Dong Hong +3 more
semanticscholar +1 more source
Journal of Allergy and Clinical Immunology, 2021 BACKGROUND Chronic urticaria (CU) is a debilitating mast cell-driven disease, often refractory to standard therapy (i.e., antihistamines). Lirentelimab, an anti-Siglec-8 monoclonal antibody, selectively inhibits mast cells and depletes eosinophils ...
S. Altrichter +8 more
semanticscholar +1 more source
Influence of the H1 Antihistamine Mepyramine on the Antibacterial Effect of Florfenicol in Pigs
Veterinary Sciences, 2021 The effect of florfenicol against Escherichia coli (E. coli) was investigated in vivo to confirm results of an in vitro study of Bruer et al. (2019), which has shown positive effects of various antibacterial agents in combination with the antihistamine ...
Gustav G. Bruer +3 more
doaj +1 more source
Structural basis for recognition of antihistamine drug by human histamine receptor
Nature Communications, 2022 The histamine receptors belong to the G protein-coupled receptor (GPCR) superfamily, and play important roles in the regulation of histamine and other neurotransmitters in the central nervous system, as potential targets for the treatment of neurologic ...
Xue-Qiang Peng +7 more
semanticscholar +1 more source
Life, 2022 Allergic rhinitis (AR) affects 20–50% of the global population. Available treatments are limited by their adverse effects. We investigated the anti-allergic effects of catechin alone and combined with cetirizine against ovalbumin-induced AR.
Mohamed A. Morsy +7 more
doaj +1 more source
Use of H-1 Antihistamine in Dermatology: More than Itch and Urticaria Control: A Systematic Review
Dermatologic Therapy, 2021 H-1 antihistamines are commonly used in dermatological practice for itch and urticaria control. The widespread expression of H-1 receptor on different cells in the skin and various biologic functions of H-1 antihistamines indicate the possible treatment ...
Chang-Yu Hsieh, T. Tsai
semanticscholar +1 more source
Basic & Clinical Pharmacology & Toxicology, 2021 Current data on use of antihistamines during breastfeeding and risks to the breastfed infant are insufficient. The aim of this systematic review was to provide an overview of studies measuring the levels of antihistamines in human breast milk, estimating
Elin Ngo +6 more
semanticscholar +1 more source