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Role of Histamine in Liver Ischemia-Reperfusion Injury-Implication for H1 Receptor Antagonist in the Clinical Application. [PDF]
TransplantationKawamoto H +14 more
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Lachnospira is a signature of antihistamine efficacy in chronic spontaneous urticaria
Experimental Dermatology, 2021Chronic spontaneous urticaria (CSU) is a mast cell‐driven disease with many advances in its aetiology and pathogenesis over the past years. The main treatment of CSU is oral second‐generation antihistamines.
Runqiu Liu +8 more
semanticscholar +1 more source
Psychosomatics, 2003
Antihistamines and their drug-drug interactions are reviewed in depth. The metabolism of "classic" or sedating antihistamines is coming to light through in vivo and in vitro studies. The polymorphic CYP 2D6 metabolic enzyme appears to be potently inhibited by many of these over-the-counter medications. The history of the discontinued "second-generation"
Scott C, Armstrong, Kelly L, Cozza
openaire +2 more sources
Antihistamines and their drug-drug interactions are reviewed in depth. The metabolism of "classic" or sedating antihistamines is coming to light through in vivo and in vitro studies. The polymorphic CYP 2D6 metabolic enzyme appears to be potently inhibited by many of these over-the-counter medications. The history of the discontinued "second-generation"
Scott C, Armstrong, Kelly L, Cozza
openaire +2 more sources
Journal of Drugs in Dermatology, 2021
Psoriasis is polygenic, interleukin (IL)-17 and IL-23 driven chronic relapsing inflammatory multisystem disease caused by a complex interplay of endogenous and environmental factors. The most common and distressing symptom in psoriasis is itch, adding significantly to the burden of disease.
Swathi, Shivakumar +6 more
openaire +3 more sources
Psoriasis is polygenic, interleukin (IL)-17 and IL-23 driven chronic relapsing inflammatory multisystem disease caused by a complex interplay of endogenous and environmental factors. The most common and distressing symptom in psoriasis is itch, adding significantly to the burden of disease.
Swathi, Shivakumar +6 more
openaire +3 more sources
2014
The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
openaire +2 more sources
The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
openaire +2 more sources
Dermatologic Clinics, 2001
In the 1990s, major improvements occurred in the therapeutic index of H1 antihistamines. The third-generation compounds promise to be more effective and nontoxic. The future major advances are likely to result from development and exploitation of non-H1 receptor-mediated antiallergic actions of these drugs.
openaire +2 more sources
In the 1990s, major improvements occurred in the therapeutic index of H1 antihistamines. The third-generation compounds promise to be more effective and nontoxic. The future major advances are likely to result from development and exploitation of non-H1 receptor-mediated antiallergic actions of these drugs.
openaire +2 more sources