Results 21 to 30 of about 74,021 (384)

Real-life experience of efficacy and safety of bilastine in the refractory cases of chronic spontaneous urticaria and its effect on the quality of life of patients

open access: yesIndian Journal of Dermatology, 2021
Introduction: Second-generation H1-antihistamines (SGAHs) are the mainstay of treatment of chronic spontaneous urticaria (CSU). Bilastine, newer non-sedating SGAHs, was recently introduced in India after the approval of the Drugs Controller General of ...
Abhishek De   +3 more
doaj   +1 more source

Expert opinion on the role of bilastine and bilastine-montelukast combination in the management of allergic rhinitis: An Indian perspective

open access: yesThe Journal of Association of Chest Physicians, 2023
In India, the burden of allergic rhinitis (AR) is enormous, comprising 55% of all patients with allergies. Intranasal corticosteroids are the recommended first-line therapy for patients with moderate-to-severe AR, particularly when nasal congestion is ...
Subir Jain   +4 more
doaj   +1 more source

Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance New drugs targeting multiple Plasmodium parasite life stages are desperately needed to combat malaria drug resistance. The antihistamine clemastine inhibits multiple parasite forms with previously unknown molecular targets.
Kuan‐Yi Lu   +5 more
semanticscholar   +1 more source

The KAAACI/KDA Evidence-Based Practice Guidelines for Chronic Spontaneous Urticaria in Korean Adults and Children: Part 2. Management of H1-Antihistamine-Refractory Chronic Urticaria

open access: yesAllergy Asthma and Immunology Research, 2020
Quite a few patients with chronic spontaneous urticaria (CSU) are refractory to H1-antihistamines, even though the dose of H1-antihistamines is increased up to 4-fold. CSU that is not controlled with H1-antihistamines results in increased disease burden.
Jeong-Hee Choi   +41 more
semanticscholar   +1 more source

Use of antihistamine medications during early pregnancy and selected birth defects: The National Birth Defects Prevention Study, 1997–2011

open access: yesBirth Defects Research, 2020
It is estimated that approximately 10–15% of pregnant women report antihistamine use during pregnancy. Although antihistamines are generally considered safe during pregnancy, results from published studies are inconsistent.
C. Hansen   +5 more
semanticscholar   +1 more source

Seasonal patterns of oral antihistamine and intranasal corticosteroid purchases from Australian community pharmacies : a retrospective observational study [PDF]

open access: yes, 2017
Acknowledgments The abstract of this paper was presented at the Respiratory Effectiveness Group 2016 Annual Summit as a poster presentation with interim findings.
Bosnic-Anticevich, Sinthia Z   +9 more
core   +3 more sources

Association between First-Generation Antihistamine Use in Children and Cardiac Arrhythmia and Ischemic Heart Disease: A Case-Crossover Study

open access: yesPharmaceuticals, 2023
Cardiotoxicity from first-generation H1-antihistamines has been debated since the 1990s. However, large-scale studies on this topic in a general pediatric population are lacking.
Ju Hee Kim   +7 more
doaj   +1 more source

Japanese Guidelines for Diagnosis and Treatment of Urticaria in Comparison with Other Countries

open access: yesAllergology International, 2012
Several guidelines for urticaria and angioedema have been published in Europe and United States since 1997. General principles for diagnosis and treatments of them are similar.
Michihiro Hide, Takaaki Hiragun
doaj   +1 more source

Differential expression of histamine receptors in the bladder wall tissues of patients with bladder pain syndrome/interstitial cystitis – significance in the responsiveness to antihistamine treatment and disease symptoms

open access: yesBMC Urology, 2019
BackgroundActivation of mast cells plays an important role in the pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC). Histamine, a mast cell-derived mediators, induced inflammation and hypersensitivity of the bladder.
Hui Shan   +6 more
semanticscholar   +1 more source

Antihistamine effects and safety of fexofenadine: a systematic review and Meta-analysis of randomized controlled trials

open access: yesBMC Pharmacology and Toxicology, 2019
As a new generation antihistamine, fexofenadine has been widely used in allergic diseases. However, there is still a lack of collective evidence regarding the antihistamine effects and safety profiles of fexofenadine relative to other antihistamine drugs
Cheng-zhi Huang   +4 more
semanticscholar   +1 more source

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