Results 51 to 60 of about 23,450 (303)

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source

Antihistamines Increase Body Mass Index Percentiles and Z-Scores in Hispanic Children

Children, 2020
The prevalence of childhood obesity has increased over the years in the United States and contributed to a rise in metabolic syndrome and non-alcoholic fatty liver disease (NAFLD).
Michelle Saad, Sabeen Syed, Maheen Ilyas, Anatoliy A. Gashev   +3 more
doaj   +1 more source

Preserved Ophthalmic Anti-Allergy Medication in Cumulatively Increasing Risk Factors of Corneal Ectasia

Biology, 2023
The prevalence of allergies is rising every year. For those who suffer from it, ocular inflammation and irritation can be inconvenient and unpleasant.
Tom Paterson, Serap Azizoglu, Moneisha Gokhale, Madeline Chambers, Cenk Suphioglu   +4 more
doaj   +1 more source

OXIME-CONTAINING CONGENERS OF THE ANTIHISTAMINE DIPHENHYDRAMINE. [PDF]

, 1974
OXIME-CONTAINING CONGENERS OF THE ANTIHISTAMINE ...
LEILANI LEE. NIXON (7982273)
core  

Cetirizine per os : exposure and antihistamine effect in the dog [PDF]

, 2018
BackgroundCetirizine is an antihistamine used in dogs, but plasma concentrations in relation to effect after oral administration are not well studied.
Ingvast-Larsson, Carina, Carina Ingvast-Larsson, Sveriges lantbruksuniversitet., Ingvast Larsson, Carina,, Carl Ekstrand, Ulf Bondesson, Mikael Hedeland, Olsén, Lena,, Bondesson, Ulf, Ekstrand, Carl,, Olsen, Lena, Lena Olsén, Ekstrand, Carl, Hedeland, Mikael   +13 more
core   +1 more source

Anomeric Amide Enabled Divergent Synthesis of Unsymmetrical Ureas, Carbamates, Thioesters, and Amides From Aldehydes

Angewandte Chemie International Edition, EarlyView.
An anomeric amide‐enabled divergent aldehyde functionalization sequence provides one‐pot access to unsymmetrical ureas, carbamates, thiocarbamates, thioesters, and amides. Key to this transformation is the formation of N‐Boc‐hydroxamate intermediates, which serve as platforms for orthogonal activation via Lossen‐type rearrangements, single‐electron ...
Jasper L. Tyler, Meiyi Zeng, Julius Wiener, Marie‐Christin Leusmann, Colin Stein, Constantin G. Daniliuc, Frank Glorius   +6 more
wiley   +1 more source

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

High-speed imaging reveals how antihistamine exposure affects escape behaviours in aquatic insect prey [PDF]

, 2019
Aquatic systems receive a wide range of pharmaceuticals that may have adverse impacts on aquatic wildlife. Among these pharmaceuticals, antihistamines are commonly found, and these substances have the potential to influence the physiology of aquatic ...
Klaminder, Jonatan,, Sveriges lantbruksuniversitet., Brodin, Tomas,, Jonsson, Micael,   +3 more
core   +3 more sources

Antihistamine poisoning [PDF]

Antihistamines are commonly used to treat allergy, dizziness and nausea. The sedating antihistamines are non-specific in their actions and often have marked anticholinergic effects.
Thomas SHL
core   +2 more sources

Scratching behavior in mice associated with IgE-mediated allergic cutaneous reaction and its pharmacological characterization

Allergology International, 1997
Scratching behavior observed after epicutaneous challenge with the antigen 2,4-dinitrofluorobenzene (DNFB) in the ear of BALB/c mice passively sensitized with anti-dinitrophenol (DNP).
Keiichi Musoh, Nobuaki Nakamura, Toshimi Sakurai, Naoki Inagaki, Hiroichi Nagai   +4 more
doaj   +1 more source