Results 71 to 80 of about 60,702 (193)
, 1969 Extracts of rat tissues (ear and abdominal skin, heart, cerebrum, spleen, kidney, lung, liver, stomach, and jejunum) were tested for their ability to antagonize histamine on the guinea pig ileum preparation.
K. I. Melville +2 more
core +1 more source
Repurposing the Antihistamine Terfenadine for Antimicrobial Activity against Staphylococcus aureus
Journal of Medicinal Chemistry, 2014 Staphylococcus aureus is a rapidly growing health threat in the U.S., with resistance to several commonly prescribed treatments. A high-throughput screen identified the antihistamine terfenadine to possess, previously unreported, antimicrobial activity ...
Jessamyn I. Perlmutter +7 more
semanticscholar +1 more source
Indian Journal of Dermatology, Venereology and Leprology, 2014 BACKGROUND Chronic urticaria not responsive to antihistamines is a difficult disease to manage. Methotrexate has been used in difficult chronic urticarias with some benefit. OBJECTIVE To evaluate the efficacy of methotrexate in the treatment of chronic
V. Sharma +4 more
semanticscholar +1 more source
Proportional impairment ratio calculation formula for an antihistamine.
, 2014 a: Number of tests showing ‘impairment’ with the named antihistamine (AH). b: Number of tests showing ‘no impairment’ with the named AH. c: Number of tests showing ‘impairment’ with all other AHs. d: Number of tests showing ‘no impairment’ with all other
Norimasa Kikuchi (462989) +6 more
core +1 more source
Treating Diphenhydramine Overdose: A Literature Review of Currently Available Treatment Methods
ToxicsFrom 2019 to 2020, antihistamines were found in 15% of all US drug overdose deaths, often co-administered with fentanyl, with 3.6% of overdose deaths due to antihistamines alone.
Jayna Patel, Joshua Edwards
doaj +1 more source
Antihistamines considerably modulate the cognitive and psychomotor performance of human volunteers
Cogent Psychology, 2016 This research investigated the modulating effects of antihistamines—Loratadine, Fexofenadine, Meclizine, and Chlorpheniramine on cognitive (executive function, memory, attention, emotion regulation), mood, psychomotor performance, and sedation in healthy
Rawshan Zannat +4 more
doaj +1 more source
Clinical and Translational AllergyBackground Although there have been significant advances in the treatment of chronic spontaneous urticaria (CSU) in recent years, there remains a lack of clear guidance on when and how to step down treatment in responders.
Murat Türk +9 more
doaj +1 more source
Metabolomic insights into variable antihistamine responses in allergic rhinitis: unveiling biomarkers for precision treatment [PDF]
BackgroundThe clinical response to antihistamine therapy exhibits substantial heterogeneity among individuals with allergic rhinitis (AR). While these medications represent a cornerstone in AR management, the molecular basis underlying differential ...
Rui Tang +10 more
core +1 more source
Acute Toxicity and Neurobehavioral Effects of Diphenhydramine in Chicks
The Journal of Poultry Science, 2012 The present study was undertaken to examine the acute toxicity (LD50) and neurobehavioral manifestations in the open-field activity and tonic immobility tests in 7-14 day-old chicks treated with the H1-receptor antagonist diphenhydramine.
Fouad K. Mohammad +2 more
doaj +1 more source
, 2014 Pooled Analysis for NSS of leukotriene antagonist versus selective H1 antihistamine for Seasonal allergic rhinitis.
Jun Wang (5906) +2 more
core +1 more source