Results 81 to 90 of about 60,702 (193)

Chemical constituents and antihistamine activity of Bixa orellana leaf extract

BMC Complementary and Alternative Medicine, 2013
BackgroundBixa orellana L. has been traditionally used in Central and South America to treat a number of ailments, including internal inflammation, and in other tropical countries like Malaysia as treatment for gastric ulcers and stomach discomfort.
Y. Yong, Z. Zakaria, A. Kadir, M. Somchit, Gwendoline Ee Cheng Lian, Z. Ahmad   +5 more
semanticscholar   +1 more source

Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization

EMBO Molecular Medicine, 2019
The current clinical care of glioblastomas leaves behind invasive, radio‐ and chemo‐resistant cells. We recently identified mammary‐derived growth inhibitor (MDGI/FABP3) as a biomarker for invasive gliomas.
Vadim Le Joncour, Pauliina Filppu, Maija Hyvönen, Minna Holopainen, S Pauliina Turunen, Harri Sihto, Isabel Burghardt, Heikki Joensuu, Olli Tynninen, Juha Jääskeläinen, Michael Weller, Kaisa Lehti, Reijo Käkelä, Pirjo Laakkonen   +13 more
doaj   +1 more source

Impact of Sedative and Non-Sedative Antihistamines on the Impaired Productivity and Quality of Life in Patients with Pruritic Skin Diseases

Allergology International, 2010
Background: The impairment that pruritic skin diseases have on patient productivity at work, in the classroom, and in daily activities is substantial and needs to be characterized.
Hiroyuki Murota, Shun Kitaba, Mamori Tani, Mari Wataya-Kaneda, Hiroaki Azukizawa, Atsushi Tanemura, Noriko Umegaki, Mika Terao, Yorihisa Kotobuki, Ichiro Katayama   +9 more
doaj   +1 more source

Establishment of a human nasal epithelium model of histamine-induced inflammation to assess the activity of fexofenadine as an inverse agonist and its link to clinical benefit

Frontiers in Pharmacology
BackgroundFexofenadine (FEX) is an antihistamine that acts as an inverse agonist against histamine (HIS) receptor 1 (H1R), which mediates the allergic reaction.
Anne Barbot, Michele Lheritier-Barrand, Margarita Murrieta-Aguttes, Maud Leonetti, Jimmy Vernaz, Song Huang, Samuel Constant, Bernadett Boda   +7 more
doaj   +1 more source

Comparative Evaluation of the Efficacy in Treating Children with Seasonal Allergic Rhinitis Using Antihistamine Combined with Ectoine Nasal Spray and Antihistamine Monotherapy: Results of an Open Randomized Study

, 2015
Objective: Our aim was to evaluate the efficacy of an ectoine nasal spray in treating children with seasonal allergic rhinitis.Methods: An open randomized study of children aged 3–17 with the aggravation of early spring hay fever.
N. V. Minaeva, D. M. Shiryaeva
core   +1 more source

The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria

Acta Dermato-Venereologica
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predictors
Yingyi Li, Rui Peng, Jingwen Xue, Yi Zhao   +3 more
doaj   +1 more source

Administration of Desloratadine for Postorgasmic Illness Syndrome in a Japanese Teenager

IJU Case Reports
Introduction Postorgasmic illness syndrome is a rare condition occurring after ejaculation. This syndrome can significantly affect the quality of life of patients.
Kaoru Ito, Ko Kobayashi, Kohei Hashimoto, Wakako Yorozuya, Ko Okabe, Seisuke Nofuji, Yasuyuki Sakai, Yuki Kyoda, Toshiaki Tanaka, Noaya Masumori   +9 more
doaj   +1 more source

Bilastine: a new antihistamine with an optimal benefit-to-risk ratio for safety during driving

, 2016
Introduction: Rational selection of a second-generation H-1-antihistamine requires efficacy and safety considerations, particularly regarding central nervous system (CNS) effects (cognitive and psychomotor function), potential for driving impairment ...
Jáuregui, I., Redondo, E., Labeaga, L., Ramaekers, J.G., Yanai, K., Farré, M., Valiente, R.   +6 more
core   +1 more source

Antihistamines: Beyond just allergy treatment

Vietnam Journal of Science, Technology and Engineering
Histamine and its receptors (H1R-H4R) are involved in several significant physiological processes and pathogenic conditions. Antihistamines, widely recognised as drugs for treating allergies, belong to the H1 antihistamine group, which targets H1R on ...
Hue T. H. Bui, Xuan-Hung Nguyen
doaj  

The common cold: The need for an effective treatment amid the FDA discussion on oral phenylephrine

Journal of Allergy and Clinical Immunology: Global
An episode of the common cold can have a significant negative impact on quality of life, mood, and daily activities. In line with this fact, there is a growing demand for health care and treatments associated with the common cold.
Emina Išerić, BSc, Joris C. Verster, PhD   +1 more
doaj   +1 more source