Results 81 to 90 of about 71,170 (384)

Night-time sedating H1-antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial

open access: yesBritish Journal of Dermatology, 2014
Many physicians believe that the most effective way to treat chronic urticaria is to take a nonsedating second‐generation H1‐antihistamine in the morning and a sedating first‐generation H1‐antihistamine, usually hydroxyzine, at night to enhance sleep ...
M. Staevska   +7 more
semanticscholar   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

open access: yesDrug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer   +4 more
wiley   +1 more source

Repurposing the Antihistamine Terfenadine for Antimicrobial Activity against Staphylococcus aureus

open access: yesJournal of Medicinal Chemistry, 2014
Staphylococcus aureus is a rapidly growing health threat in the U.S., with resistance to several commonly prescribed treatments. A high-throughput screen identified the antihistamine terfenadine to possess, previously unreported, antimicrobial activity ...
Jessamyn I. Perlmutter   +7 more
semanticscholar   +1 more source

Effects of Dimenhydrinate on Motor Behavior and Vascular Function: Possible Implications for the Field of Sports

open access: yesDrug Testing and Analysis, EarlyView.
Regarding cardiovascular effects, DMH decreased vascular reactivity to phenylephrine and acetylcholine. We observed that the combination of DPH and 8‐Cl‐T was identified as the responsible for increasing blood pressure and heart rate in the biological model used.
Jazmín Flores‐Monroy   +3 more
wiley   +1 more source

Antihistamines considerably modulate the cognitive and psychomotor performance of human volunteers

open access: yesCogent Psychology, 2016
This research investigated the modulating effects of antihistamines—Loratadine, Fexofenadine, Meclizine, and Chlorpheniramine on cognitive (executive function, memory, attention, emotion regulation), mood, psychomotor performance, and sedation in healthy
Rawshan Zannat   +4 more
doaj   +1 more source

Comorbid Medical Conditions as Predictors of Overall Survival in Glioblastoma Patients [PDF]

open access: yes, 2019
Glioblastoma (GBM) is an aggressive central nervous system tumor with a poor prognosis. This study was conducted to determine any comorbid medical conditions that are associated with survival in GBM.
Broaddus, William C.   +9 more
core   +1 more source

A randomized placebo-controlled double-blind pilot study of methotrexate in the treatment of H1 antihistamine-resistant chronic spontaneous urticaria.

open access: yesIndian Journal of Dermatology, Venereology and Leprology, 2014
BACKGROUND Chronic urticaria not responsive to antihistamines is a difficult disease to manage. Methotrexate has been used in difficult chronic urticarias with some benefit. OBJECTIVE To evaluate the efficacy of methotrexate in the treatment of chronic
Vinod K. Sharma   +4 more
semanticscholar   +1 more source

Actinidia spp. (Kiwifruit): A Comprehensive Review of Its Nutraceutical Potential in Disease Mitigation and Health Enhancement

open access: yesFood Frontiers, EarlyView.
Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha   +7 more
wiley   +1 more source

Comparison of Triple Combination Oral Sedation Regimens for Pediatric Dental Treatment [PDF]

open access: yes, 2019
Purpose: Compare the efficacy of two benzodiazepines (diazepam or midazolam) in combination with meperidine and hydroxyzine for pediatric dental sedation.
Henderson, Brett H
core   +1 more source

Antihistamines for the common cold [PDF]

open access: yes, 2015
Background : The common cold is an upper respiratory tract infection, most commonly caused by a rhinovirus. It affects people of all age groups and although in most cases it is self limiting, the common cold still causes significant morbidity ...
De Sutter, An   +2 more
core   +2 more sources

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