Results 101 to 110 of about 69,436 (336)
Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease [PDF]
, 2013 The aim of the study was to characterize pharmacokinetics of tiotropium solution 5 µg compared to powder 18 µg and assess dose-dependency of tiotropium solution pharmacodynamics in comparison to placebo.
Cornelissen, PJG +7 more
core +1 more source
Long‐Term Cost Utility Analysis of Endoscopic Sinus Surgery: Analysis of 5‐Year Outcomes
The Laryngoscope, EarlyView.This study utilizes a cohort‐style Markov decision tree economic model to evaluate the long‐term (5‐year) cost‐effectiveness of endoscopic sinus surgery versus medical management for patients with chronic rhinosinusitis. The results show that the endoscopic sinus surgery strategy cost more ($63,296.27) but yielded increased quality‐adjusted life years (
Dara R. Adams +5 more
wiley +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Previous studies have suggested a benefit to early functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis (CRS). With the approval of T2 biologics for CRS with nasal polyps (CRSwNP), it is important to re‐evaluate FESS timing in relation to T2 biologic utilization.
Radhika Duggal +4 more
wiley +1 more source
Does cost sharing really reduce inappropriate prescriptions? [PDF]
, 2010 This paper explores different empirical strategies to examine the effect of cost sharing for prescription drugs in some dimensions of medication-related quality, namely the probability of inappropriate prescription drug use among United States seniors ...
Costa-i-Font, Joan +1 more
core
Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assay [PDF]
, 2008 Introduction: We report on a double-blind, vehicle-controlled, single-center confirmatory study with random assignment. The purpose of the study was to investigate the topical bioavailability of different topical corticosteroid formulations in healthy ...
Ashton RE +17 more
core +1 more source
Rheumatology &Autoimmunity, EarlyView.This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley +1 more source
Frontiers in Pharmacology, 2019 Allergic rhinitis (AR) is a chronic upper respiratory disease estimated to affect between 10 and 40% of the worldwide population. The mechanisms underlying AR are highly complex and involve multiple immune cells, mediators, and cytokines.
Annabelle M. Watts +3 more
doaj +1 more source
Effect of the antihistamines, brompheniramine maleate and triprolidine hydrochloride, on performance in man. [PDF]
, 1979 AN Nicholson
openalex +1 more source
Small Methods, EarlyView.This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli +6 more
wiley +1 more source