Results 101 to 110 of about 9,174 (251)

Model-based exploration of the rationality of off-label use of cetirizine in Chinese pediatric patients: a prospective cohort study

Frontiers in Pharmacology
Aims: Cetirizine is frequently administered at an increased dosage in clinical practice and recommended by several guidelines. Nonetheless, the pharmacokinetic (PK) profile and real-world safety data remain insufficient in the Chinese pediatric ...
Wei Liu, Wei Liu, Wei Liu, Zhiyuan Tan, Ping Yang, Ping Yang, Zhiheng Yu, Xueting Yao, Pengxiang Zhou, Pengxiang Zhou, Ling Liu, Wei Zhou   +11 more
doaj   +1 more source

Using Patient Profiles To Guide The Choice Of Antihistamines In The Primary Care Setting In Malaysia: Expert Consensus And Recommendations

, 2019
Abdullah Baharudin,1 Amir Hamzah Abdul Latiff,2 Kent Woo,3 Felix Boon-Bin Yap,4 Ing Ping Tang,5 Kin Fon Leong,6 Wai Seong Chin,7 De Yun Wang8 1Department of Otorhinolaryngology – Head and Neck Surgery, School of Medical Sciences, Universiti Sains ...
Chin WS, Abdul Latiff AH, Wang DY, Yap FBB, Baharudin A, Leong KF, Woo K, Tang IP   +7 more
core  

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Acute and Chronic Urticaria: Prevalence, Etiologies, Diagnosis, and Treatment

Journal of Mazandaran University of Medical Sciences, 2020
Urticaria is a pruritic skin lesion characterized by rapid onset of blanchable central wheals and marginal flare. Urticaria diseases are categorized on the basis of their duration, etiology, and causes.
Javad Ghaffari, Negar Ghaffari
doaj  

The polysaccharide Pullulan improves the initial steps of allergen‐specific immunotherapy in dogs

Veterinary Record, EarlyView.
Abstract Background Allergen‐specific immunotherapy (AIT) is the only aetiological treatment for canine atopic dermatitis (CAD). Pullulan, a polysaccharide with immunomodulatory properties, may enhance AIT outcomes when combined with allergens such as recombinant Dermatophagoides farinae 2 (Der f 2).
Franco Martini, Ana Rostaher, Claude Favrot, Nina M. Fischer   +3 more
wiley   +1 more source

A Delphi Consensus on Clinical Features, Diagnosis, and Treatment of Chronic Rhinosinusitis With Nasal Polyps in the ASEAN Region

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah, Revadi Govindaraju, Salina Husain, Jin Keat Siow, Pongsakorn Tantilipikorn, Neville Wei Yang Teo, De Yun Wang, Deasi Anggraini, Tze Choong Charn, Chao‐Wu David Chin, Dichapong Kanjanawasee, Maung Maung Khaing, Jern‐Lin Leong, Luan Viet Tran, Harvinder Singh, Ing Ping Tang, Kim Thye Mark Thong, Gil M. Vicente, Yoke Yeow Yap, Soma Subramaniam   +19 more
wiley   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Efficacy of second-generation antihistamines in patients with allergic rhinitis and comorbid asthma

, 2011
Background and aims. Allergic rhinitis (AR) and asthma share common mediators, cytokines, and chemokines from mast cells and basophils that are central to the complex cascade of events involved in the inflammatory response.
Jorge Maspero, Claus Bachert, Bachert, Claus, Maspero, Jorge   +3 more
core   +1 more source

Distinct Nasal Microbiome Profiles and Prediction Model for Allergic Rhinitis, Nonallergic Rhinitis, and Healthy Children

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
The alpha and beta diversity of the nasal microbiome differed among children with allergic rhinitis (AR), nonallergic rhinitis (NAR), and healthy controls (HCs). Compared to HC, AR had more Escherichia‐Shigella, Negativicoccus, and Campylobacter, while NAR had more Dolosigranulum and fewer Enterobacteriaceae.
Kantima Kanchanapoomi, Iyarit Thaipisuttikul, Perapon Nitayanon, Witchaya Srisuwatchari, Punchama Pacharn, Nualanong Visitsunthorn, Orathai Jirapongsananuruk   +6 more
wiley   +1 more source

Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment

, 2016
Non-small cell lung cancer (NSCLC) is one of the deadliest cancers worldwide. In search for new NSCLC treatment options, we screened a cationic amphiphilic drug (CAD) library for cytotoxicity against NSCLC cells and identified several CAD antihistamines ...
Christian Dehlendorff, Luise Cederkvist, Jan Stenvang, Marja Jäättelä, Søren Friis, Dehlendorff, Christian, Friis, Soren, Nikolaj H.T. Petersen, Cederkvist, Luise, Mellemgaard, Anders, Petersen, Nikolaj H. T., Nylandsted, Jesper, Atul Anand, Kell Østerlind, Osterlind, Kell, Ellegaard, Anne-Marie, Vind, Anna C., Anna C. Vind, Jesper Nylandsted, Stenvang, Jan, Anne-Marie Ellegaard, Anand, Atul, Anders Mellemgaard, Jaattela, Marja   +23 more
core   +1 more source