Results 251 to 260 of about 44,402 (291)
Some of the next articles are maybe not open access.
Psychosomatics, 2003
Antihistamines and their drug-drug interactions are reviewed in depth. The metabolism of "classic" or sedating antihistamines is coming to light through in vivo and in vitro studies. The polymorphic CYP 2D6 metabolic enzyme appears to be potently inhibited by many of these over-the-counter medications. The history of the discontinued "second-generation"
Scott C, Armstrong, Kelly L, Cozza
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Antihistamines and their drug-drug interactions are reviewed in depth. The metabolism of "classic" or sedating antihistamines is coming to light through in vivo and in vitro studies. The polymorphic CYP 2D6 metabolic enzyme appears to be potently inhibited by many of these over-the-counter medications. The history of the discontinued "second-generation"
Scott C, Armstrong, Kelly L, Cozza
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Journal of Drugs in Dermatology, 2021
Psoriasis is polygenic, interleukin (IL)-17 and IL-23 driven chronic relapsing inflammatory multisystem disease caused by a complex interplay of endogenous and environmental factors. The most common and distressing symptom in psoriasis is itch, adding significantly to the burden of disease.
Swathi, Shivakumar +6 more
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Psoriasis is polygenic, interleukin (IL)-17 and IL-23 driven chronic relapsing inflammatory multisystem disease caused by a complex interplay of endogenous and environmental factors. The most common and distressing symptom in psoriasis is itch, adding significantly to the burden of disease.
Swathi, Shivakumar +6 more
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2014
The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
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The discovery of histamine, its physiological role and reversal of its pharmacological effects by antihistamines takes us on a journey through the origins of modern physiology and the rising understanding of pharmacology at the end of the 19th and the early part of the 20th centuries.
Martin K, Church, Marcus, Maurer
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Dermatologic Clinics, 2001
In the 1990s, major improvements occurred in the therapeutic index of H1 antihistamines. The third-generation compounds promise to be more effective and nontoxic. The future major advances are likely to result from development and exploitation of non-H1 receptor-mediated antiallergic actions of these drugs.
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In the 1990s, major improvements occurred in the therapeutic index of H1 antihistamines. The third-generation compounds promise to be more effective and nontoxic. The future major advances are likely to result from development and exploitation of non-H1 receptor-mediated antiallergic actions of these drugs.
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Dermatologic Clinics, 1991
Antihistamines are a diverse group of drugs, each possessing the ability to inhibit various actions of histamine. Because they act principally through competitive inhibition of the histamine receptor, they are helpful as a means of preventing rather than reversing these actions.
L E, Herman, J D, Bernhard
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Antihistamines are a diverse group of drugs, each possessing the ability to inhibit various actions of histamine. Because they act principally through competitive inhibition of the histamine receptor, they are helpful as a means of preventing rather than reversing these actions.
L E, Herman, J D, Bernhard
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Journal of the American Medical Association, 1947
Any medicament, no matter how valuable, may do great harm if it is employed indiscriminately. The fame of the new antihistaminic drugs has become so widespread, indeed, that they are often prescribed merely to satisfy the patient's curiosity. A critical inventory of their value is therefore indicated.
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Any medicament, no matter how valuable, may do great harm if it is employed indiscriminately. The fame of the new antihistaminic drugs has become so widespread, indeed, that they are often prescribed merely to satisfy the patient's curiosity. A critical inventory of their value is therefore indicated.
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Annals of Otology, Rhinology & Laryngology, 1976
Antihistamines may be used to maximum benefit for the allergic patient if the physician adheres to four guidelines. These guidelines are based upon 1) an appreciation of certain structural and pharmacologic differences among antihistamines, and 2) an understanding of their mechanism of action.
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Antihistamines may be used to maximum benefit for the allergic patient if the physician adheres to four guidelines. These guidelines are based upon 1) an appreciation of certain structural and pharmacologic differences among antihistamines, and 2) an understanding of their mechanism of action.
openaire +2 more sources