Results 11 to 20 of about 518 (129)

LC‐MS based metabolite profiling, in‐vitro antioxidant and in‐vivo antihyperlipidemic activity of Nigella sativa extract

eFood, 2023
The aim of this study was to identify the bioactive phytoconstituents present in the aqueous extract of Nigella sativa and also, to evaluate the antioxidant and antihyperlipidemic activity in Wistar rats.
Amit Kumar Shrivastava, Laxmi Shrestha, Buddhi Raj Pokhrel, Bishal Joshi, Gopal Lamichhane, Bojana Vidović, Niranjan Koirala   +6 more
doaj   +2 more sources

Dual Ligand-Enabled Nondirected C─H Olefination of (Hetero)Arenes for the Synthesis of Clickable Derivatives. [PDF]

Chemistry
We report an efficient method for late‐stage installation of “clickable” alkyne groups into diverse (hetero)arenes. Using a dual‐ligand palladium catalyst that combines an NASA ligand with an N‐heterocycle, an acrylate unit bearing a terminal alkyne can be introduced via nondirected C─H activation.
Braga T, Hergert M, van Gemmeren M.
europepmc   +2 more sources

Association of the Fibrosis-4 Index With Indices of Atherosclerosis in Patients With Type 2 Diabetes: An Exploratory Subanalysis of a Prospective Observational Cohort Study. [PDF]

J Diabetes Res
Background Metabolic dysfunction–associated steatotic liver disease (MASLD) is characterized by insulin resistance and metabolic syndrome, with type 2 diabetes mellitus (T2DM) as a major risk factor. Additionally, MASLD has been linked to liver fibrosis, which is associated with increased cardiovascular risk. Although noninvasive liver fibrosis markers
Tanaka K, Okada Y, Mita T, Torimoto K, Sato F, Katakami N, Yoshii H, Nishida K, Tanaka Y, Ishii R, Gosho M, Shimomura I, Watada H.   +12 more
europepmc   +2 more sources

Ameliorative effects of phlorotannin-rich fraction of Sargassum tenerrimum in high-fat diet and low dose streptozotocin-induced metabolic changes and oxidative stress in diabetic rats [PDF]

Journal of HerbMed Pharmacology, 2023
Introduction: Type 2 diabetes mellitus (T2D) is a progressing polygenic disease demanding a multitargeted treatment strategy. Sargassum tenerrimum (ST) is a marine brown alga with potentially bioactive chemicals that could be used as innovative ...
Narasimha Kumar Godlaveti Vijay, Chitra Vellapandian   +1 more
doaj   +1 more source

Effects of Papaya (Carica papaya L.) as Anti- Hyperlipidemia: A Systematic Review [PDF]

International Journal of Nutrition Sciences, 2022
Papaya (Carica papaya L) is one of the fruits that is easily found in Asian countries. Papaya has been studied to have good benefits in hyperlipidemia.
Herviana Herviana, Dono Indarto, Brian Wasita, Sudana Pasaribu   +3 more
doaj   +1 more source

Pharmacokinetics Study of Herb-Drug Interaction of <i>Berberine</i> and Glipizide in Beagle Dogs Using UPLC-MS/MS. [PDF]

Int J Anal Chem
Based on the establishment and validation of a UPLC‐MS/MS method for detecting glipizide in beagle plasma, the herb–drug interaction (HDI) between berberine and glipizide was studied. After gradient elution separation of glipizide and internal standard, multiple reaction monitoring was used for detection in positive ion mode. The ion reactions used for
Qi H, Wang W, Zhang X, Shang B.
europepmc   +2 more sources

Screening significance of systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) in coronary heart disease of symptomatic youth. [PDF]

Immun Inflamm Dis
(1) Coronary heart disease in youth is difficultly recognized in the early stage. (2) Systemic inflammation index (SII) and systemic inflammation response index (SIRI) were independently associated with the presence of young CHD. (3) SII and SIRI provide a new method for screening patients with CHD in youth.
Wang C, Yan W, Ren M, Zhong L.
europepmc   +2 more sources

A Phase I, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety and Tolerance of Oil Palm Phenolics (OPP) in Healthy Volunteers

Frontiers in Pharmacology, 2022
Background and aim: Oil palm aqueous by-products rich in phenolic content are known as oil palm phenolics (OPP), and pre-clinical research has shown that OPP has great potential to be further developed as an anti-hyperlipidemic agent.
Nur Balqis Muhammad Ismail Tadj, Nurul ‘Izzah Ibrahim, Qodriyah Haji Mohd Saad, Tg Mohd Ikhwan Tg Abu Bakar Sidik, Soon-Sen Leow, Syed Fairus, Isa Naina Mohamed   +6 more
doaj   +1 more source

Antioxidant and antihyperlipidemia effects of artichoke on hyperlipidemia-induced male rabbits

The Pharma Innovation
Qasim Abbas Chafat, Suhad J Hadi, Mohammed A Aboktifa   +2 more
exaly   +2 more sources

Cardio Protection and Antiatherosclerotic Effects of <i>Solanum incanum</i> (Lin.) Extracts in Animal Models. [PDF]

Scientifica (Cairo)
Solanum incanum is a bushy perennial herb which is used for treatment of various ailments in East Africa including stomach pain, toothaches, ulcers, and cardiovascular diseases. However, there is scarcity of data on its safety, and its effect on the physiology of the cardiovascular system.
Mburu SN, Ngugi MP, Mwonjoria JK.
europepmc   +2 more sources