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Antihypertensive Agents 1962–1968
1969Seven years ago Schlittler, Druey, and Marxer [207] reported on antihypertensive agents in a previous volume of this series. Since this review appeared, research in the field of antihypertensive drugs has made steady progress. Although spectacular breakthroughs — exemplified by such pioneering feats as the discoveries of reserpine, hydralazine ...
O, Schier, A, Marxer
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New Antihypertensive Agents: Benefit of Treatment
Journal of Cardiovascular Pharmacology, 1992Large-scale end-point trials have demonstrated that antihypertensive treatment reverses the risk of stroke attributable to high blood pressure and probably reduces the incidence of myocardial infarction. Despite this major achievement in therapeutics, substantial goals still need to be achieved.
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A 1996 update on antihypertensive agents
Current Opinion in Cardiology, 1996Seven new classes of antihypertensive agents that are currently under development are outlined. Clinical studies of neutral endopeptidase inhibitors and angiotensin II receptor blockers are described. Experimental studies are described involving endothelin inhibitors, and clinical and experimental studies of a new multiple action antihypertensive agent,
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Centrally Acting Antihypertensive Agents
Journal of Cardiovascular Pharmacology, 1988In spite of the fact that plasma catecholamine levels, baroreflex activity, and hemodynamic pattern significantly change with age and drugs whose action is mediated via the sympathetic nervous system might be expected to cause different effects, the limited available data suggest that both alpha-methyldopa and clonidine lower blood pressure to a ...
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Chapter 6 Antihypertensive Agents
1990Publisher Summary Cardiovascular disease accounts for more expenditures on health care than any other diagnostic category and hypertension is the most prevalent cardiovascular condition. While unit costs for hypertension treatment are low, aggregate costs are enormous because of the large and growing population of patients who are treated ...
Edward W. Petriilo +2 more
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Perioperative management of antihypertensive agents
Minerva MedicaA large proportion, possibly over half, of patients presenting for preoperative evaluation will be taking antihypertensive agents. The multiple classes of agents and their use in different combinations can make management decisions challenging. Poor blood pressure control and lack of evidence or conflicting evidence for certain agents can further ...
Jason F, Shiffermiller +2 more
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Haemodynamic effects of antihypertensive agents
1978In most patients with hypertension the cause is unknown and so are most of the mechanisms initiating and maintaining the elevated blood pressure. If these mechanisms were fully understood and were correctable by drugs, a truly rational therapy would be possible.
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