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Diuretics in primary hypertension – Reloaded [PDF]
Diuretics have long been cherished as drugs of choice for uncomplicated primary hypertension. Robust mortality and morbidity data is available for diuretics to back this strategy.
Sundeep Mishra
doaj +2 more sources
UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study [PDF]
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz +5 more
wiley +2 more sources
Diuretics and Hypokalemia [PDF]
We have studied hypokalemic action of different diuretics in a cooperative study on 28 patients and our results are as follows: I. 28 patients (18 male and 10 female) were the subject of our present study. 2. E. C. G.
Ali A. Handjani +2 more
doaj +3 more sources
Elevation of the serum urate is well recognized as an invariable side effect of treatment with all diuretics except those agents, such as triamterene and amiloride, that retain potassium. Practitioners cannot fail to appreciate the frequency of hyperuricemia in many of their patients because, even in asymptomatic patients, it is regularly brought to ...
Emmerson, Bryan T., Emmerson B.T.
openaire +5 more sources
Association between changes in loop diuretic dose and outcomes in acute heart failure
Aims Little is known about the association between the starting of or dose changes in loop diuretics during acute heart failure (AHF) hospitalization and post‐discharge outcomes. We investigated the clinical impact of starting loop diuretics and changing
Yuta Seko +27 more
doaj +1 more source
Tactics of antihypertensive therapy during COVID-19 pandemic
Results of foreign and Russian studies indicate a higher mortality rate of patients with concomitant cardiovascular diseases (CVD) due to the new coronavirus infection COVID-19.
Valery I. Podzolkov +4 more
doaj +1 more source
Diuretici su lijekovi koji smanjuju volumen ekstracelularne tekućine povećavanjem izlučivanja soli i vode putem bubrega. Mogu se podijeliti prema kemijskoj strukturi, mehanizmu i mjestu djelovanja: diuretici Henleove petlje (furosemid, bumetanid ...
Mavrić, Žarko +2 more
core +5 more sources
All diuretics used in the treatment of hypertension are not the same
Summary– Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and chlorthalidone have frequently been considered in the same category as thiazide diuretics, but there is no ...
Serkan Asil, Enver Atalar
doaj +1 more source
Preparation for radioiodine therapy: How to increase therapeutic efficacy and accelerate unbound radioiodine excretion [PDF]
nema
Matović Milovan
doaj +1 more source
Impact of Albumin Binding Function on Pharmacokinetics and Pharmacodynamics of Furosemide
Background and Objectives: Albumin binding of the loop diuretic furosemide forms the basis for its transport to the kidney and subsequent tubular secretion, which is a prerequisite for its therapeutic effects.
Gerd Klinkmann +6 more
doaj +1 more source

