Results 1 to 10 of about 5,055 (197)

Comparative effectiveness and prescribing trends of modified release versus immediate release indapamide in patients with hypertension: cohort study [PDF]

BMJ Medicine
Objective To investigate the prescribing trends of indapamide, a thiazide-like diuretic, and the long term comparative effectiveness of modified release versus immediate release indapamide.Design Cohort study.Setting IQVIA Medical Research Data UK ...
Li Wei, Esther W Chan, Yang Chen, Jacob George, Bryan Williams, Chengsheng Ju, Isla S Mackenzie, Robert Flynn, Vincent Ka Chun Yan, Thomas MacLennan MacDonald   +9 more
doaj   +6 more sources

CLINICAL EFFICACY OF MONOTHERAPY WITH INDAPAMIDE IN PATIENTS WITH ARTERIAL HYPERTENSION OF THE I-II DEGREES [PDF]

Рациональная фармакотерапия в кардиологии, 2016
Aim. To assess antihypertensive efficacy of monotherapy with indapamide (Akripamide, Akrihin, Russia) and its influence on blood levels of carbohydrates, lipids and electrolytes in patients with essential hypertension (EH). Methods. 30 patients with EH I-
E. Yu. Тourkassova, T. G. Volkova, E. M. Idrissova, E. M. Vorobyeva, R. S. Karpov   +4 more
doaj   +2 more sources

ASSESSMENT OF THERAPEUTICAL EQUIVALENCY OF ORIGINAL AND GENERIC INDAPAMIDE IN HYPERTENSIVE PATIENTS BY RANDOMIZED CROSS-OVER STUDY

Рациональная фармакотерапия в кардиологии, 2015
Aim. To develop a protocol for comparison of efficacy and safety of original drugs with generic ones and to apply this protocol for comparison of generic indapamide (Indap) with original indapamide in two presentations: short acting (Arifon) and long ...
N. P. Kutishenko, V. V. Yakusevich, A. D. Deev, S. Y. Martsevich   +3 more
doaj   +3 more sources

Effects of Some Antihypertensive Drugs on the Metabolism and Pharmacokinetics of Indapamide in Rats

Journal of Pharmacy & Pharmaceutical Sciences, 2012
Purpose. Indapamide, a non-thiazide antihypertensive diuretic agent, has been widely coadministered with other classes of antihypertensive agents to reach target systolic blood pressure.
Fang Yan, Ying Hu, Bin Di, Ping Lei He, Guibin Sun   +4 more
doaj   +1 more source

Protective Action of Indapamide, a Thiazide-Like Diuretic, on Ischemia-Induced Injury and Barrier Dysfunction in Mouse Brain Microvascular Endothelial Cells

Journal of Pharmacological Sciences, 2007
The aim of the present study was to elucidate the effects of indapamide on ischemic damage to the blood-brain barrier (BBB) in vitro. The ischemia /reperfusion conditions employed here significantly decreased the viability of mouse brain capillary ...
Tsuyoshi Nishioku, Fuyuko Takata, Atsushi Yamauchi, Noriko Sumi, Ikumi Yamamoto, Akiko Fujino, Mikihiko Naito, Takashi Tsuruo, Hideki Shuto, Yasufumi Kataoka   +9 more
doaj   +1 more source

LONG-TERM THERAPY WITH INDAPAMIDE IN ELDERLY AND SENILE PATIENTS WITH HYPERTENSION: CARDIORENOPROTECTIVE EFFECTS AND INFLUENCE ON QUALITY OF LIFE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To estimate cardiorenoprotective effect of 12-month therapy by indapamide in elderly and senile patients with arterial hypertension (HT) and its influence on quality of life.Material and methods. 40 elderly and senile patients with HT were examined.
M. E. Statsenko, T. G. Sherbakova, S. V. Belenkova, O. E. Sporova   +3 more
doaj   +3 more sources

Simultaneous determination of indapamide, perindopril and perindoprilat in human plasma or whole blood by UPLC-MS/MS and its pharmacokinetic application

Journal of Pharmaceutical Analysis, 2018
Simple and sensitive methods were developed for the determination of indapamide, perindopril and its active metabolite perindoprilat in human plasma or whole blood by hyphenated ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS ...
Yi Tao, Sheng Wang, Lei Wang, Min Song, Taijun Hang   +4 more
doaj   +1 more source

Effectiveness and safety of the ACE inhibitor and diuretic combination in postmenopausal women with arterial hypertension

Кардиоваскулярная терапия и профилактика, 2011
Aim. To assess effectiveness, tolerability, and safety of combined antihypertensive therapy (AHT) with an ACE inhibitor (perindopril) and thiazide-like diuretic (indapamide) in postmenopausal women with arterial hypertension (AH).
G. G. Semenkova, E. E. Matvienko
doaj   +1 more source

Association between Food/UGT2B7 Polymorphisms and Pharmacokinetics/Pharmacodynamics Properties of Indapamide in Healthy Humans

Biomedicines, 2023
Indapamide is an effective and safe antihypertensive medication showing a beneficial effect in combination with other antihypertensive agents regarding morbidity and mortality.
Banaz Abbas, Nagwa A. Sabri, Amal A. El-Khouly   +2 more
doaj   +1 more source

UHPLC-UV Method for Simultaneous Determination of Perindopril Arginine and Indapamide Hemihydrate in Combined Dosage Form: A Stability-Indicating Assay Method

Scientia Pharmaceutica, 2018
Perindopril arginine and Indapamide hemihydrate in combination were proven to have a synergistic antihypertensive impact when compared with the use of each component alone.
Naser F. Al-Tannak
doaj   +1 more source