Results 21 to 30 of about 113,350 (308)

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

A review of olmesartan medoxomil monotherapy: antihypertensive efficacy similar to that of other angiotensin II receptor blocker/hydrochlorothiazide combinations?

Кардиоваскулярная терапия и профилактика, 2011
Angiotensin II receptor blockers (ARBs) have been available in the United Statessince 1995. These agents have demonstrated antihypertensive efficacy at least similar to that of agents from other antihypertensive classes.
M. Greathouse
doaj   +1 more source

Antihypertensive medication use during pregnancy in a real-world cohort of patients diagnosed with a hypertensive disorder of pregnancy

Frontiers in Cardiovascular Medicine, 2023
Hypertensive disorders of pregnancy (HDP) are rising in prevalence and associated with adverse maternal and infant health outcomes. Current guidelines recommend labetalol, nifedipine, and methyldopa as acceptable first-line agents to treat HDP in ...
Julian E. Garcia, Ian R. Mulrenin, Anh B. Nguyen, Matthew S. Loop, Matthew S. Loop, Melissa A. Daubert, Rachel Urrutia, Craig R. Lee   +7 more
doaj   +1 more source

Treatment of atherosclerotic renovascular hypertension: review of observational studies and a meta-analysis of randomized clinical trials. [PDF]

, 2015
open9Atherosclerotic renal artery stenosis can cause ischaemic nephropathy and arterial hypertension. We herein review the observational and randomized clinical trials (RCTs) comparing medical and endovascular treatment for control of hypertension and ...
Caielli, P, Calò, Frigo, Anna Chiara, Maiolino, G, Miotto, Diego, Pengo, Mf, Rossi, Gianpaolo, Rossitto, G, Seccia, Teresa Maria   +8 more
core   +1 more source

Uncontrolled and apparent treatment resistant hypertension: a cross-sectional study of Russian and Norwegian 40–69 year olds

BMC Cardiovascular Disorders, 2020
Background Uncontrolled hypertension is a major cardiovascular risk factor. We examined uncontrolled hypertension and differences in treatment regimens between a high-risk country, Russia, and low-risk Norway to gain better understanding of the ...
Jakob Petersen, Sofia Malyutina, Andrey Ryabikov, Anna Kontsevaya, Alexander V. Kudryavtsev, Anne Elise Eggen, Martin McKee, Sarah Cook, Laila A. Hopstock, Henrik Schirmer, David A. Leon   +10 more
doaj   +1 more source

Comparative effectiveness of first-line antihypertensive drug classes on the maintenance of estimated glomerular filtration rate (eGFR) in real world primary care

Scientific Reports, 2023
Renin-angiotensin system inhibitors (RASi), particularly angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs), are commonly used in the treatment of hypertension and are recommended for kidney protection ...
Qiao Gao, Ngiap Chuan Tan, Mong Li Lee, Wynne Hsu, Jason Choo   +4 more
doaj   +1 more source

BP Reduction, Kidney Function Decline, and Cardiovascular Events in Patients without CKD. [PDF]

, 2018
BACKGROUND AND OBJECTIVES: In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive systolic BP treatment (target
Dias, C, Leitão, L, Magriço, R, Neves, J, Vieira, M   +4 more
core   +1 more source

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]

, 2003
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O., Diener, H. C., Glahn, J., Hamann, Gerhard F., Weimar, C.   +4 more
core   +1 more source

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia [PDF]

, 2011
OBJECTIVE: Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 diabetes using oral ...
Bodmer, Michael, Jick, Susan S., Krähenbühl, Stephan, Meier, Christian, Meier, Christoph R.   +4 more
core   +2 more sources

Combination therapy in the treatment of hypertension

Drugs in Context, 2018
Hypertension is a major preventable risk factor for atherosclerosis and ischemic heart disease. Although modern and effective antihypertensive drugs are available, most patients remain with a suboptimal blood pressure control.
Alberto Francisco Rubio-Guerra
doaj   +1 more source